Below is a listing of facilities, services, programs, and expertise available to Neuroscience investigators. Access may vary depending on the facility or program. For additional information, please follow links and contact information for each entry. If you would like to add an entry, please contact the Office of Neuroscience Research.
| Facility | Services offered | Contact |
Alafi Neuroimaging | Confocal and multiphoton microscopy; digital whole-slide scanning; atomic force microscopy | Kris Hyrc |
AMP (Anatomic and Molecular Pathology) Lab | Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging | Neha Dahiya |
Animal Behavior | Phenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholds | David Wozniak |
Animal Surgery | Models for stroke, traumatic brain injury | Ernie Gonzales |
Bakewell Neuroimaging | Confocal and multiphoton microscopes for live or fixed tissue imaging; low light imaging system; FRET/FRAP; upright or inverted microscope capability; post acquisition work station (Metamorph, Image J, Adobe Photoshop) | Dennis Oakley, Paul Taghert |
Biology - Low Light Imaging | Low Light Imaging for bioluminescence | Luciano Marpegan |
Biology Imaging | Confocal and deconvolution microscopy | Dianne Duncan |
Biomedical Informatics | Web tools, sequence analysis, biospecimen inventory management, clinical study data management (consultation), microarray analyses (expression, aCGH, SNP, ChIP-CHIP, and ChIP-Seq) | help@bmi.wustl.edu |
Biostatistics Consulting | Design of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of data | Ken Schechtman |
Brain, Behavior and Performance Unit (ICTS) | Testing and other support for neurologic, psychiatric and psychometric parameters, muscle strength and function, quantified measures of movement, performance-based measures of daily living activities and quality-of-life measures; infrastructure for common database collection, retrieval and transfer of all research information, and technical personnel | Ling Yan |
Business Development Core (ICTS) | Review research designs to identify potential commercialization opportunities, serve as matchmaker between Investigators and Industrial partners, conduct educational programs in technology transfer for investigators, staff and students | Brad Castanho |
Career Development and Translational Research in Pediatrics (ICTS) | Expand translational research paradigm to include investigation for child health problems, serve as a catalyst for building research teams that include a continuum of researchers consisting of basic science, translational, and clinical investigators within and across multiple departments and schools | Terrie Inder |
Center for Clinical Research Ethics (ICTS) | Education, consultation and research on topics of clinical research ethics | Chiji Ogbuka |
Central Neuroimaging Data Archive | Storage and analysis of MRI, PET, and CT imaging data | Dan Marcus |
Clinical Research Training Center (ICTS) | Infrastructure to foster clinical research training and career development for predoctoral students, house-staff, postdoctoral fellows and faculty by integrating diverse training programs into a single location and administrative umbrella | Rachel Driskell, Jacquelyn Rice |
Clinical Research Unit (ICTS) | Facilities, equipment and staffing for in-patient and out-patient clinical research | Jina Loduca |
Clinical Trials Unit (ICTS) | Research space, equipment, and nursing support for a wide range of clinical studies | Ann Doyle |
Community Health Care Practitioners (ICTS) | Consultation about community-based patient recruitment and formation of practice-based research networks | Jane Garbutt, Kathy Mandrell |
Community Organizations (ICTS) | Enhance long-term, collaborative research relationships with community-based partner organizations focused on healthcare delivery and health promotion | Consuelo Hopkins Wilkins |
Community-Based Recruitment and Retention (ICTS) | Recruitment to link populations that have been underrepresented in research to health information, physician referrals and clinical trials | Erin Murdock |
Confocal Microscopy (Dept of Cell Biology & Physiology) | Zeiss LSM-510 META confocal microscope, Stallion Fluorescence Imaging microscope | Bob Wilkinson |
Deep-Etch Electron Microscope (DEEM) (Dept of Cell Biology & Physiology) | Quick-freezing of biological samples, subsequent preparation of quick-frozen samples for electron microscopy | John Heuser, Robyn Roth |
Electron Microscopy (Dept of Cell Biology & Physiology) | Tissue processing for morphology and/or immunolabeling, technical support for embedding, sectioning, immunoprocessing, scoping and darkroom services | Marilyn Levy |
Excitability Imaging Core | Calcium imaging | Kris Hyrc |
Genome Center: DNA and RNA Analysis | Genotyping and expression, all commercial microarray formats, custom array design and manufacture, RNA/DNA QC analysis, microarray processing and data analysis | Seth Crosby, Mike Heinz |
Genome Center: Investigatory Sequencing | Mapping, whole genome sequencing, clone sequencing, sequence refinement, EST and cDNA sequencing | Lucinda Fulton |
Histology and Microscopy (Dept of Developmental Biology) | Full service histology, Zeiss Apotome structured resolution microscope, stereoscope, brightfield/fluorescence microscopes, transmission EM, scanning EM | Bill Coleman, Marlene Scott |
Human Genetics and Genomics (ICTS) | Large scale generation and analysis of genomic variants | ictsgenetics@dsgmail.wustl.edu |
Human Imaging Unit (ICTS) | Advanced imaging technology, equipment and expertise to support basic and translational inpatient and outpatient clinical research | Center for Clinical Imaging Research |
In Vitro Physiology | In vitro brain slice preparations, whole-cell recording (cultured neurons or transfected cells), data analysis | Steve Mennerick |
In Vivo Physiology | EEG, EMG, evoked synaptic responses from dentate granule cell layer, assessment of tetanus-induce long-term synaptic potentiation | Kel Yamada |
Lifestyle Intervention Research Core (ICTS) | Specialized nutrition services, behavioral assessment and therapy, training in sensory evaluation techniques and lifestyle behavior-change therapy, image processing and analysis services
| Beth Henk |
Mouse Genetics | Production and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivations | Mia Wallace |
Multiple Sclerosis Research Interest Group | Multiple Sclerosis animal models - EAE | Anne Cross |
Our Community, Our Health (ICTS) | Disseminate relevant and culturally appropriate health information and actively engage the St. Louis community in partnerships to help address local health disparities | Consuelo Hopkins Wilkins |
Pain Center | Behavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugs | Rob Gereau |
Pediatric Clinical Research Unit (ICTS) | Space, nursing and bionutritional support for clinical research projects conducted with children at Washington University in St. Louis | pcru@kids.wustl.edu |
Protein and Nucleic Acid Chemistry Laboratories (PNACL) | Automated DNA sequencing, synthetic oligonucleotides, Edman degradation protein sequencing | Erin Ramshur, Misty Veschak, Greg Grant |
Proteomics | Advanced mass spectrometry and data analysis tools for survey protein identification and quantification in biological fluids and tissues, consultation on experimental design, selection of analytical platforms and sample preparation, integrated platform for discovery and confirmation of candidate protein biomarkers in biological fluids and tissues | help@proteomics.wustl.edu |
Regulatory Support Center (ICTS) | Regulatory Core, Participant Advocacy and Ombudsman Core, and Recruitment Enhancement Core to assist in overcoming organizational barriers, navigating through regulatory requirements for human research, and recruiting adequate numbers of appropriate research participants for studies | Courtney Acree |
RNAi | Viral vector-based RNAi technology to alter gene function in primary cultures | rnairequest@watson.wustl.edu |
Sensory Function | Standard noninvasive functional assays of inner ear/auditory brainstem function, and retina/central visual pathways | Kevin Ohlemiller |
Transgenic Vectors | Design and construction of mouse transgenes and gene targeting vectors using recombineering technology; mouse ES cell screening (pcr and southern blot) | Renate Lewis |
Translational Pathology & Molecular Phenotyping (ICTS) | Facilitate collection, processing, storage, and molecular analysis of biospecimens from participants enrolled on clinical and translational research studies, assist in design and execution of studies focused on genomic and molecular analyses of study participant biospecimens | Mark Watson |
Viral Vectors |
Assist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment available
| Mingjie Li, Joy Snider |
