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Office of Neuroscience Research > Resources and Facilities > Shared Resources

Shared Resources

Below is a listing of facilities and expertise available to all Neuroscience investigators.  If you would like to add a shared resource, please contact the Office of Neuroscience Research.

To search for a shared resource, enter a keyword or phrase.

Shared Services, Equipment, and Expertise
Facility Services offered Contact

 Alafi Neuroimaging

Confocal and multiphoton microscopy; digital whole-slide scanning Kris Hyrc
AMP (Anatomic and Molecular Pathology) Lab Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging  
Animal Behavior

 Phenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholds

David Wozniak
Animal Models Models for stroke, traumatic brain injury Ernie Gonzales
 Bakewell Neuroimaging

Confocal and multiphoton microscopes for live or fixed tissue imaging; low light imaging system; FRET/FRAP; upright or inverted microscope capability; post acquisition work station (Metamorph, Image J, Adobe Photoshop)

Dennis Oakley, Paul Taghert
 Biology Imaging

Confocal and deconvolution microscopy

Olga Pontes
Biology - Low Light Imaging Low Light Imaging for bioluminescence Luciano Marpegan
Biomedical Informatics

Web tools, sequence analysis, biospecimen inventory management, clinical study data management (consultation), microarray analyses (expression, aCGH, SNP, ChIP-CHIP, and ChIP-Seq)

help@bmi.wustl.edu
Biostatistics Consulting Design of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of data Ken Schechtman
Central Neuroimaging Data Archive (CNDA) Storage and analysis of MRI, PET, and CT imaging data Dan Marcus
Histology and Microscopy

Full service histology, Zeiss Apotome structured resolution microscope, stereoscope, brightfield/fluorescence microscopes, transmission EM, scanning EM

Howard Wynder
In Vitro Physiology In vitro brain slice preparations, whole-cell recording (cultured neurons or transfected cells), data analysis Steve Mennerick
In Vivo Physiology EEG, EMG, evoked synaptic responses from dentate granule cell layer, assessment of tetanus-induce long-term synaptic potentiation Kel Yamada
 Mouse Genetics Production and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivations Mia Wallace
Multiple Sclerosis Research Interest Group

Multiple Sclerosis animal models - EAE

Anne Cross
Pain

Behavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugs

Rob Gereau
Protein and Nucleic Acid Chemistry Laboratories (PNACL) Automated DNA sequencing, synthetic oligonucleotides, Edman degradation protein sequencing Erin Ramshur, Misty Veschak, Greg Grant
 Proteomics   Reid Townsend
RNAi

Viral vector-based RNAi technology to alter gene function in primary cultures

rnairequest@watson.wustl.edu

Sensory Function Standard noninvasive functional assays of inner ear/auditory brainstem function,  and retina/central visual pathways Kevin Ohlemiller
 Transgenic Vectors Design, construction of mouse transgenes and gene targeting vectors using recombineering technology; mouse ES cell screening (pcr and southern blot) Renate Lewis
Viral Vectors Assist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment available Mingjie Li, Joy Snider
Washington University Center for Cellular Imaging (WUCCI) The goal of the WUCCI is to provide reliable and affordable access to state-of-the-art cellular imaging technologies, provide professional guidance in experimental design, sample preparation and data analysis, develop and apply new imaging technologies and work collaboratively with WUSM researchers to advance our understanding of human health and disease. James Fitzpatrick
Washington University Zebrafish Facility This facility will allow large-scale, collaborative projects that would not be possible for individual investigators, helping scientists understand human development and disease, from birth defects and cancer to muscle and nerve disorders. Stephen Canter