“Multimaterial Multifunctional Fibers for Biomedical Applications”

Hosted by the Department of Biomedical Engineering (BME)

Abstract: Advanced human-machine interfaces have seen rapid growth in the past decades. Although the semiconductor industry has enabled electronic and optical devices with unprecedented sensing and modulation capabilities, the conventional devices based on rigid materials are intrinsically not compatible with soft tissues. Therefore, flexible, biocompatible, and multi-functional devices and systems are highly demanded. My research focuses on addressing the key interface challenges between humans and the physical world using a multimaterial multifunctional fiber approach. Fabricated using a scalable thermal drawing method, these fibers are miniaturized, highly flexible, multifunctional, and biocompatible, making them ideal candidates for biomedical implant applications. In this talk, I will discuss the application of these fibers in neural engineering, tumor research, and cardiovascular systems. In particular, we have developed a three dimensional and multifunctional deep brain interface using fibers. These fibers allow for large volume deep brain stimulation and recording in freely behaving mice with a small surgical burr hole. We have also developed optoelectronic fibers integrated with plasmonic nanoparticles for highly sensitive and selective chemical sensing. In addition, robotic fibers have been developed which can navigate through blood vessels for intracardiac EGM, pacing, and bioimpedance sensing. Finally, optical fibers with microfluidic channels and electrodes have been developed as a promising candidate for photodynamic therapy in tumor treatment and monitoring.

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For inquiries contact Mimi Hilburg.