ICTS/Venture Café 3rd Thursdays Seminar: Tim Peterson (WashU Genetics), Shin-ichiro Imai (WashU Developmental Biology) – “Can aging be reversed? Latest in anti-aging research and therapeutics”

January 16, 2020
4:00 pm - 5:00 pm
@4240 Duncan Avenue Havana Room, 2nd floor (Cortex Campus)

“Can aging be reversed? Latest in anti-aging research and therapeutics”

Tim Peterson: “Healthspan therapeutics that increase the ratio of “young” to “old” genes”
Shin-ichiro Imai: “Achieving Productive Aging: Understanding the systemic regulation of aging and longevity in mammals and developing an anti-aging intervention”


NOTE time

Tim Peterson (WashU Genetics)
“Healthspan therapeutics that increase the ratio of “young” to “old” genes”
As our global population lives longer, there is increasing interest in healthspan – the period of life that one is free from aging-associated conditions, such as Alzheimer’s and osteoporosis. Healthspan is recognized as important because of its impact on quality of life and health care costs. We’ve developed a healthspan metric we call the “Y/O Ratio” based on genes we’ve categorized as either “young” or “old”. We applied our metric to identify potential anti-aging drugs with a Y/O Ratio greater than 1. In the coming months we will test these drugs in mouse models of Alzheimer’s, which is a prevalent aging condition with limited treatment options.

Shin-ichiro Imai (WashU Developmental Biology
“Achieving Productive Aging: Understanding the systemic regulation of aging and longevity in mammals and developing an anti-aging intervention”
I will introduce the cutting-edge front of aging/longevity research in our lab, focusing on the inter-tissue communications among the hypothalamus, skeletal muscle, and adipose tissue.  I will also talk about our efforts of translating our preclinical results to humans and developing an anti-aging intervention using an NAD intermediate called nicotinamide mononucleotide (NMN).

The Institute of Clinical and Translational Sciences (ICTS) Precision Medicine team invites you to an on-going collaboration with Venture Café.  On the third Thursday of every month , ICTS Precision Medicine hosts a session featuring WashU faculty working in translational genomics/precision medicine areas. Talks are typically oriented toward biotechnology, diagnostics, informatics, start-ups and precision interventions based on medical genomics innovations.

For more information visit the ICTS Precision Medicine website.