Exploring recent publications in ion channel and excitability research, from fundamental mechanisms to disease

The Ion Channels Journal Club is a core activity of the Center for the Investigation of Membrane Excitability Diseases (CIMED).

When: 1:00p Mondays
Where: Zoom conference
Organizer: Paula Reynolds (CIMED)

2020 Fall Schedule

August – October

August 17, 2020

Jian Gao (Nichols lab, WashU Cell Biology and Physiology)

“Macrolides Selectively Inhibit Mutant KCNJ5 Potassium Channels That Cause Aldosterone-producing Adenoma”JCI 2020

August 24, 2020

Conor McClenaghan (Nichols lab, WashU Cell Biology and Physiology)

“A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans”  Current Biology 2020

September 14, 2020

Sunjoo Lee (Nichols lab, WashU Cell Biology & Physiology)

“Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells”  Cell Reports 2020

September 21, 2020

Nathan York (Nichols lab, WashU Cell Biology & Physiology)

“Enhanced Expression of β Cell CaV3.1 Channels Impairs Insulin Release and Glucose Homeostasis”    PNAS 2020

September 28, 2020

Yihao Jiang (Chanda lab, WashU Anesthesiology)

“Structure of the Human Sodium Leak Channel NALCN”  Nature (2020)

October 12, 2020

John Petroff (Cheng lab, WashU Anesthesiology)

“Shared Structural Mechanisms of General Anaesthetics and Benzodiazepines”  Nature (2020)

October 19, 2020

Mimi Guo (Huebsch lab, WashU Biomedical Engineering)

“Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes”  Nature Communications (2020)

October 26, 2020

Kathryn Mangold (Silva lab, WashU Biomedical Engineering)

“Predicting Functional Effects of Missense Variants in Voltage-gated Sodium and Calcium Channels” Science Translational Medicine (2020)

For Zoom information contact Paula Reynolds.

November 9, 2020

Zhihui He (Yuan lab, WashU Cell Biology and Physiology)

“Structural Basis for pH Gating of the Two-pore Domain K+ Channel TASK2”  Nature (2020)

November 16, 2020

Ryan Bitter (Yuan lab, WashU Cell Biology and Physiology)

“Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport” Biophysical Journal (2016)

November 23, 2020

Vinay Idikuda (Chanda lab, WashU Anesthesiology)

“CNGA3 Acts as a Cold Sensor in Hypothalamic Neurons”  eLife (2020)

November 30, 2020

Ashu Kumar (Sah lab, WashU Medicine)