Exploring recent publications in ion channel and excitability research, from fundamental mechanisms to disease
The Ion Channels Journal Club is a core activity of the Center for the Investigation of Membrane Excitability Diseases (CIMED).
When: 1:00p Mondays
Where: Zoom conference
Organizer: Paula Reynolds (CIMED)
2020 Fall Schedule
August – October
August 17, 2020
Jian Gao (Nichols lab, WashU Cell Biology and Physiology)
- Supplemental publication: “A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating”. Neuron, . 2008
August 24, 2020
Conor McClenaghan (Nichols lab, WashU Cell Biology and Physiology)
“A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans” Current Biology 2020
- Supplementary publication: “Endogenous Opioids Contribute to Insensitivity to Pain in Humans and Mice Lacking Sodium Channel Nav1.7”. Nature Communications 2015
September 14, 2020
Sunjoo Lee (Nichols lab, WashU Cell Biology & Physiology)
“Site-Specific Incorporation of Two ncAAs for Two-Color Bioorthogonal Labeling and Crosslinking of Proteins on Live Mammalian Cells” Cell Reports 2020
September 21, 2020
Nathan York (Nichols lab, WashU Cell Biology & Physiology)
“Enhanced Expression of β Cell CaV3.1 Channels Impairs Insulin Release and Glucose Homeostasis” PNAS 2020
September 28, 2020
Yihao Jiang (Chanda lab, WashU Anesthesiology)
“Structure of the Human Sodium Leak Channel NALCN” Nature (2020)
October 12, 2020
John Petroff (Cheng lab, WashU Anesthesiology)
“Shared Structural Mechanisms of General Anaesthetics and Benzodiazepines” Nature (2020)
October 19, 2020
Mimi Guo (Huebsch lab, WashU Biomedical Engineering)
“Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes” Nature Communications (2020)
October 26, 2020
Kathryn Mangold (Silva lab, WashU Biomedical Engineering)
“Predicting Functional Effects of Missense Variants in Voltage-gated Sodium and Calcium Channels” Science Translational Medicine (2020)
For Zoom information contact Paula Reynolds.
November 9, 2020
Zhihui He (Yuan lab, WashU Cell Biology and Physiology)
“Structural Basis for pH Gating of the Two-pore Domain K+ Channel TASK2” Nature (2020)
November 16, 2020
Ryan Bitter (Yuan lab, WashU Cell Biology and Physiology)
“Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport” Biophysical Journal (2016)
November 23, 2020
Vinay Idikuda (Chanda lab, WashU Anesthesiology)
“CNGA3 Acts as a Cold Sensor in Hypothalamic Neurons” eLife (2020)
November 30, 2020
Ashu Kumar (Sah lab, WashU Medicine)
