The Synapse Journal Club explores recent publications in the area of neuroscience and physiology with a focus on the neuronal synapse and its function. 

Explore the archives below.

Synapse Journal Club Schedule – Spring 2020

February 14, 2020   Mark Rutherford (WashU Otolaryngology)

    “Conformational pathway provides unique sensitivity to a synaptic mGluR” (Nature Communications (2019)

** From March 6 – March 20, Synapse J Club will meet jointly with the Nanocourse, “Autoimmune Disorders of the Synapse”.   
All are welcome to join!

CANCELLED – March 13, 2020 Nanocourse

    Cellular mechanisms of NMDAR encephalitis

CANCELLED – March 20, 2020 Nanocourse


Synapse Journal Club Schedule – Fall 2019

Synapse Journal Club Schedule – Fall 2018

September 21, 2018

Andrew Sauerbeck
WashU Neurology

“Superresolution Imaging of Chemical Synapses in the Brain”  Neurotechnique (2010)

October 5, 2018

Rachel Hendrix
Cirrito Lab, WashU Neurology

“LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent” eLife (2017)

October 19, 2018

Peter Lambert
Mennerick Lab,  WashU Psychiatry

“Dedicated Population for Reward Coding in the Hippocampus” Neuron (2018)

November 16, 2018

Geraldine Kress
WashU Neurology

“Light Affects Mood and Learning through Distinct Retina-Brain Pathways” Cell (2018)

December 7, 2018

Luis Boero
Rutherford Lab , WashU Otolaryngology

“Enhancement of the Medial Olivocochlear System Prevents Hidden Hearing Loss” Journal of Neuroscience (2018)

Synapse Journal Club Schedule – Fall 2017/Spring 2018

Spring – 1st and 3rd Fridays at 10:00 am
Biotechnology 129

February 2, 2018
Jane Hettinger (Cirrito Lab, WashU Neurology)

“Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory”  Nature (2018)

March 16, 2018
Jenny Shu (Mennerick Lab) 

“Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites” Nat Struct Mol Biol. (2017)

April 6, 2018
Hannah Frye (Moron-Concepcion Lab)
“Homeostatic Plasticity in the Hippocampus Facilitates Memory Extinction.” Cell Reports (2018)

May 4, 2018
Mark Rutherford (Otolaryngology)
“Compartmentalization of antagonistic Ca(2+) signals in developing cochlear hair cells” PNAS (2018)

May 18, 2018
Carla Yuede (Neurology)
“Aß Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus.” Cell (2018)


September 15, 2017
Min-Yu Sun (Mennerick lab)
 “Assembly rules for GABAA receptor complexes in the brain”  eLife (2017)

November 3, 2017 
Michael Strickland (1st year neuroscience student)
“Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held” J. Neurosci (2017)

November 17, 2017
Peter Lukasiewicz
“Slow AMPAR Synaptic Transmission Is Determined by Stargazin and Glutamate Transporters” Neuron. (2017)

December 1, 2017
Matt Tso (Herzog Lab)
“Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep Wake Cycle” Neuron (2017)

December 15, 2017
Steve Mennerick
“Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake” Cell Metab. (2017)

Synapse Journal Club Schedule – Spring 2017

Spring – Every other Friday, 10:00am  NOTE exception on March 31!
Biotechnology 129

February 3, 2017 (donuts!)
Geraldine Kress  

“REM sleep selectively prunes and maintains new synapses in development and learning” Nature Neuroscience (2017)

February 17, 2017
Courtney Sobieski (Mennerick lab)

“GLUT4 Mobilization Supports Energetic Demands of Active Synapses” Neuron (2017)

March 3, 2017
Jane Hettinger (Cirrito lab)

“Optogenetic control of synaptic composition and function” Neuron (2017)

March 17, 2017
Peter Lukasiewicz 

“Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation” Nature Communications (2016)

March 31, 2017*** NOTE: 9a start; visiting applicants (and donuts!)
Steve Mennerick

“Axonal Endoplasmic Reticulum Ca2+ Content Controls Release Probability in CNS Nerve Terminals” Neuron (2017)

April 21, 2017
Carla Yuede 

“The Retromer Supports AMPA Receptor Trafficking During LTP” Neuron (2017)

May 5, 2017
John Cirrito


May 19, 2017
Min-Yu Sun 
(Mennerick lab)

“GARLH Family Proteins Stabilize GABAA Receptors at Synapses” Neuron (2017)

Synapse Journal Club Schedule – Fall 2013/Spring 2014

FALL – Fridays, 10:00am
Biotech 228

September 20, 2013
Jane Hettinger (Cirrito Lab) 

“Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Ab Oligomer Bound to Cellular Prion Protein” Neuron (2013)

October 18, 2013
Christine Emnett (Mennerick Lab)

“Impaired D-Serine-Mediated Contransmission Mediates Cognitive Dysfunction in Epilepsy” JNeurosci (2013)

November 15, 2013
EJ Brace (DiAntonio Lab)

“Spontaneous and evoked release are independently regulated at individual active zones” JNeurosci (2013)

November 22, 2013
Courtney Sobieski (Mennerick Lab)

“Amyloid-β1–42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1”JNeurosci (2013)

December 13, 2013
Gerry Kress (Mennerick Lab)

“Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake” Nature Neuroscience (2013)