Archives: IDDRC Seminars (formerly, Autism Seminar Series)

A history of past seminars.

2023 Fall Schedule

September 13, 2023

Erlanger Room, McDonnell Sciences (Medical Campus)

Inaugural IDDRC Symposium

“Bridging the divide: Integrating neuroscience methods and models to drive discovery”

Join us for an opportunity to identify areas of intersection in neuroscience research taking place at Washington University and foster productive collaborations among labs that investigate related topics using different methods.

October 20, 2023

Benjamin Garcia (WashU Biochemistry & Molecular Biophysics)

“Quantitative proteomics for understanding epigenetic mechanisms in human disease”

November 8, 2023

Zoom/Renard 2nd floor conference room (Medical Campus)

Stephen Sheinkopf, David Beversdorf (University of Missouri)

  • Stephen Sheinkopf: “Studying the emergence of autism in general population and enriched likelihood cohorts
  • David Beversdorf: “Stress and its implications for pharmacology and development in ASD”

December 8, 2023

Location: Zoom conference, for inquiries contact

Mustafa Sahin (Harvard University)

“Cellular and Circuit Deficits in Tuberous Sclerosis”

2022/2023 Schedule

October 3, 2022

Christina Gurnett (WashU Neurology) and Joseph Dougherty (WashU Genetics)

“State of The IDDRC@WUSTL”

November 14, 2022

Harrison Gabel (WashU Neuroscience), Susan Maloney, Alexxai Kravitz (WashU Psychiatry), Jennifer Strahle, Peter Yang (WashU Neurosurgery)

“Engelhardt Family Foundation Innovation Fund (EF2I) Pilot Award Speaker Series”

December 12, 2022

Aravinda Chakravarti (New York University)

“The Phenotypic Effects of Enhancer Variation”

January 9, 2023

Maya Chopra (Boston Children’s Hospital), Heather Hazlett (University of North Carolina, Chapel Hill), Virginia Lanzotti (WashU Psychiatry)

Moderated by Philip R.O. Payne (WashU Medicine)

IDDRC-CTSA Brain Gene Registry: Paired Genotypic, Phenotypic and EHR data to Advance the Understanding of Rare Brain Gene Variants

February 13, 2023

Mirella Dapretto (University of California, Los Angeles)

“Neuroimaging in Early Infancy: Mechanistic Insights on Autism Susceptibility”

March 13, 2023

David Page (Massachusetts Institute of Technology/HHMI)

“Connecting the sex chromosomes to sex differences in health and disease”

Related reading materials:

April 10, 2023

Nico Dosenbach (WashU Neurology)

“A Somato-Cognitive Action Network alternates with effector regions in motor cortex”

May 22, 2023

Time: 1:00p
Location: McDonnell Sciences 928 (Medical Campus)

Stewart Mostofsky (Johns Hopkins University)

“Action in Autism: How Moving Lampposts from Human Eyes to Computer Vision Can Help Address Heterogeneity and Advance Clinical Care”

2021/2022 Schedule

September 13, 2021

Tychele Turner (WashU Genetics)

“Insights from Short-read and Long-read Whole-genome Sequencing in Autism”

CANCELLED – October 11, 2021

Mirella Dapretto (University of California, Los Angeles)

“Brain-based markers of autism risk and resilience”

Supplemental reading

November 8, 2021

Sundari Chetty (Stanford University)

“Modeling brain overgrowth in autism using pluripotent stem cells”

Reading materials

December 13, 2021

Harrison Gabel (WashU Neuroscience)

“Investigating the Cellular and Molecular Basis of Overgrowth and Intellectual Disability Disorders”

January 10, 2022

Mariah Hoye (Duke University Medical Center)

“Molecular and Cellular Mechanisms of DDX3X Syndrome”

Reading materials

February 14, 2022

Joshua Ewen (Kennedy Krieger Institute)

“Testing competing theories of autism using large datasets”

March 14, 2022

Varun Warrier (University of Cambridge)

“Genetic Correlates of Phenotypic Heterogeneity in Autism”

April 11, 2022

Cynthia Rogers (WashU Psychiatry), Christopher Smyser (WashU Neurology), Damien Fair (University of Minnesota)

“Introduction to the HEALthy Brain and Child Development Study”

May 9, 2022

Stephan Sanders (University of California, San Francisco)

“Understanding the female protective effect in autism”

2020/2021 Schedule

October 12, 2020 

Kevin Pelphrey (University of Virginia)

“Toward Precision Medicine for Autism(s)”

November 9, 2020 

Linda Richards (WashU Dept. of Neuroscience/University of Queensland)

“Wiring the brain for function”

December 14, 2020 

Kelly Botteron (WashU Psychiatry)

“MRI based exploration of Early Brain Development in Infants with Down Syndrome: Comparison with Other Developmental Disabilities”

January 11, 2021 

Brian O’Roak (Oregon Health & Science University)

“Genomic Approaches for Understanding Autism”

Mini Series: Toward advances in IDD treatment through maternal-fetal medicine

January 25, 2021

Gregor Kasprian (Medical University of Vienna)

“Fetal MRI in IDD” 

February 8, 2021 

Ritsuko Pooh (CRIFM Clinical Research Institute of Fetal Medicine Pooh Maternity Clinic, Osaka, Japan)

“Fetal Sonographic Neuroimaging in IDD”

March 8, 2021

Tania Attie-Bitach (Hospital Necker-Enfants Malades and Université Paris Descartes)

“Fetal Pathology in Monogenic IDD Syndromes”

April 12, 2021

Ebony Boyce Carter, Michael Bebbington (WashU Obstetrics/Gynecology)

“A Pregnancy Lifecourse Approach to Childhood Intellectual and Developmental Disabilities: The Role of Fetal Surgery”

May 10, 2021

Marsha Michi (Case Western University)
James DuBois (WashU Bioethics Research Centre)

“Ethical Considerations in Fetal Testing and Intervention in the Context of Genetic Risk for IDD”

2019/2020 Schedule

September 16, 2019

Jeffrey Neil (WashU Neurology)
“Using Diffusion MRI to Study Early Cortical Development”

Relevant publication:

October 28, 2019

Ilya Monosov (WashU Dept. of Neuroscience)
“Cortical and sub-cortical mechanisms of information seeking and curiosity”

Relevant in press publication:

November 18, 2019

Tychele Turner (WashU Genetics)
“Autism through the lens of the genome”

Relevant publications:

CANCELLED (inclement weather) – December 16, 2019

Susan Perlman (WashU Psychiatry)
“Examining Interpersonal Neural Synchronization in Autism Spectrum Disorder”

Relevant publications:

January 13, 2020 – NOTE time: 4:30-5:30p

Elizabeth Berry-Kravis (Rush University)

“Gene Based Clinical Trials in Neurological Disorders of Development: Presenting 2 WU Scientific Teams in Conversation with Liz Berry-Kravis”

Craig Zaidman (WashU Neurology) “Spinal Muscular Atrophy Gene Therapies”
Patricia Dickson (WashU Pediatrics) “Aromatic l-Amino Acid Decarboxylase (AADC) Deficiency”

February 17, 2020

Corina Anastasaki (Gutmann lab, WashU Neurology)

“Neurofibromatosis type 1: a model system to study cognition, behavior and brain development”

Related articles:

CANCELLED – April 20, 2020

Natasha Marrus (WashU Psychiatry)

CANCELLED – May 18, 2020

2018/2019 Schedule

September 17, 2018

Tamara Hershey 
WashU Psychiatry, Neurology and Radiology
“Neurophenotyping a rare monogenic disorder: Lessons from Wolfram Syndrome”

related articles:

October 29, 2018

Matthew Lalli
Milbrandt and Mitra Labs, WashU Genetics
“CRANIUM – A Cas9-based platform to discover common mechanisms of rare disease genes”

related articles:

December 17, 2018

Jason Yi
WashU Dept. of Neuroscience
“Phenotypic and mechanistic insights from variant analysis of UBE3A”

related articles:

January 14, 2019

Annapurna Poduri
Harvard University
“Epilepsy Genetics: A Gateway to Mosaicism in Neurodevelopmental Disorders”

February 18, 2019

Harrison Gabel
WashU Dept. of Neuroscience

“From genetics to mechanism: understanding epigenetic disruption in autism and related disorders”

Related articles:

March 18, 2019

Gabriel Haller
Gurnett and Dobbs Lab, WashU Neurology and Orthopaedic Surgery

“High-throughput functional characterization of genetic variation in human disease”

Related articles:

April 15, 2019

Laura Jansen
WashU Neurology

“Mechanistic Links Between Epilepsy and Autism in the mTORopathies”

Related articles:

May 20, 2019

Flash Talks

Cynthia Ortinau (WashU Pediatrics)“Altered prenatal brain development in congenital heart disease”

Rafael Galindo (WashU Neurology)“Neuroprotective actions of gonadotropins in the injured developing brain”

Stephanie Morris (WashU Neurology)“Genotype-Phenotype Correlation in NF1-ASD”

Bhooma Aravamuthan (WashU Neurology)“Pathophysiology of dystonia after neonatal brain injury”

Zachary Vesoulis (WashU Pediatrics)“Late failure of cerebral autoregulation in hypoxic-ischemic encephalopathy is associated with brain injury”

Jessica Chubiz (WashU Prematurity Research Center): “Prematurity Research Center (PRC) and Women & Infants Health Specimen Consortium (WIHSC) Resources”

2017/2018 Schedule

September 25, 2017

NOTE: 4:00p Start Time

Pat Levitt 
Keck School of Medicine at USC
“Addressing the Biological Origins of Autism Heterogeneity”

October 16, 2017

Anna Kukekova
University of Illinois, Urbana-Champaign
“What can tame and aggressive foxes tell us about genetics of interactive social behavior?”

Related articles:

December 18, 2017

Meghan Swanson
University of North Carolina
“Learning to Talk: The Neurodevelopment of Emerging Language”

Related articles:

January 22, 2018

Nathan Kopp
Dougherty Lab, WashU Genetics
“Current and emerging approaches to understanding Williams Syndrome using human genetics and mouse models” 

Related article:

February 19, 2018

NOTE: 4:00p Start Time

Suma Jacob
University of Minnesota
“Common versus heterogeneous pathways in autism: examples from neuropeptide and phenotype studies”

March 19, 2018

Pamela Valnegri
Bonni Lab, WashU Dept. of Neuroscience
“Deregulation of Ubiquitin Signaling in Autism Spectrum Disorders”

Related article: 

April 16, 2018

Peter Tsai
University of Texas, Southwestern
“Cerebro-Cerebellar Circuits in Autism”

Related articles:

May 21, 2018

John Pruett Jr.
WashU Psychiatry
“MRI-Based ASD Outcome Prediction”

Related articles:

2016/2017 Schedule

October 17, 2016

Claire Weichselbaum and John Constantino
WashU Psychiatry
Infant Eye Movement Links Genetic Susceptibility with Social Impairment in Autism”

Related article:

November 28, 2016

Joseph Dougherty
WashU Genetics
“Using Genetics and Gene Expression to Define Candidate Circuits for ASD and Neurogenetic Disorder”
Related article:

December 19, 2016

Kristen Kroll
WashU Developmental Biology
“Modeling Neurodevelopmental Disorders in Human Pluripotent Stem Cell-Derived Neurons”

Related article: 

January 17, 2017

Mike Wong
WashU Neurology
“Tuberous Sclerosis as a Model of Autism and Intellectual Disability”

Related articles:

February 20, 2017

Terra Barnes
WashU Dept. of Neuroscience
“Towards an Animal Model of Stuttering”

March 20, 2017

Mike Gaffrey
WashU Psychiatry
“Early Preventive Intervention for Autism During Infancy: An Emerging Program at WashU”

April 17, 2917

Anna Kukekova
University of Illinois, Urbana-Champaign

May 15, 2017

Vitaly Klyachko
WashU Biomedical Engineering/Cell Biology & Physiology
“Presynaptic dysfunction in Fragile X syndrome” 

2015/2016 Schedule

September 21, 2015

Harrison Gabel
WUSTL Anatomy & Neurobiology
“The neuron-specific epigenome in development and disease” 

Related articles:

October 19, 2015

John Constantino
WUSTL Psychiatry
“Presenting the new Intellectual and Developmental Disabilities Research Center at W.U. by way of example: 
A plan to tap its  diverse core structure to help elucidate the neurobiology of risk and resilience in familial autism”

Related articles: 

November 16, 2015

Anish Mitra
WUSTL Radiology
“Spontaneous infra-slow brain activity and Autism”

Related articles:

Jeffery Lichtenhan
WUSTL Otolaryngology
“Strong medial olivocochlear reflexes in children with Autism are mediated by hyperacusis, not Autism per se”

December 21, 2015

Adam Eggebrecht
WUSTL Radiology
“How do we bridge genetics, brain structure and function and behavior to understand neurodevelopmental disorders?” 

 Related articles:

January 19, 2016

Christina Gurnett
WUSTL Neurology
“Interpretation of human gene variation with high-throughput functional analysis”

February 15, 2016

Dustin Baldridge
WUSTL Psychiatry
“An Update on Clinical Whole Exome Sequencing at Washington University: A Resource for Translational Research in Autism”  

Related articles:

March 21, 2016 

Susan Maloney
WUSTL Genetics
“Early Environmental Insult: Using genetic tools to dissect circuitry mediating long-term behavioral outcomes”

Related articles:

Sabine Mous
WUSTL Psychiatry
“Autism spectrum symptomatology in genetic neurocognitive developmental disorders: focus on Tuberous Sclerosis Complex and Fragile X syndrome “

Related articles: 

April 18, 2016 

Andrew Yoo
WUSTL Developmental Biology
Generation of specific subtypes of human neurons by direct conversion of fibroblasts for modeling neurological diseases”

Related article:

May 16, 2016

Zohreh Talebizadeh
University of Missouri, Kansas City
“Genetics of autism: integrated approaches and thinking outside the box!”

Related articles:

2014/2015 Schedule

November 15, 2014 

Dr. Barbara Warner
WUSTL Pediatrics

Related publications:

December 15, 2014

Dr. Jeanne Nerbonne

WUSTL Developmental Biology

Related publications:

January 10, 2015 

Dr. Joseph Dougherty
WUSTL Genetics
Arising opportunities from human genetics for developing new autism models”

Related publications:

February 9, 2015 

Dr. Daniel Povinelli
University of Louisiana

Susan Fitzpatrick
President, James S. McDonnell Foundation
“On the ‘rise’ of autism and its early detection: experimental, societal, and ethical implications”

Related Publications:

April 20, 2015 

Natasha Marrus
WUSTL Psychiatry

Bryan McGill
WUSTL Neurology

Related publications:

May 9, 2015 

Ju Huang
WUSTL Anatomy & Neurobiology
“Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent Synaptic Plasticity in the Mammalian Brain”

Related Publications: