Access to equipment, expertise, reagents and other resources. Click on the name of the facility for full descriptions.
- Many of these resources are made possible by WashU Centers and Institutes.
- Want to add your core/resource to the list below? Contact the ONR.
| Facility | Resources offered | Contact |
| Anatomic and Molecular Pathology Core Lab (AMP) | Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging | Charles Eby |
| Animal Behavior Core | Phenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholds | Susan Maloney, Carla Yuede |
| Biologic Therapy Core Facility | Develops and manufactures novel biologic, cellular and other state-of-the-art therapeutics; labels MAB for use in Immuno-radiotherapy treatments or as PET imaging agents in oncological settings; routine tissue processing and cryopreservation; provides Research grade Lentiviral vectors; provides regulatory and administrative support in the therapeutic agent approval process. | Todd Fehniger |
| Biology Imaging | Confocal and deconvolution microscopy | Dianne Duncan |
| Biostatistics Consulting | Design of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of data | Ken Schechtman |
| Center for Administrative Data Research (CADR, ICTS) | The Center for Administrative Data Research (CADR) serves to provide leadership and training in the use of health services administrative data in clinical epidemiologic, health services and outcomes research. | Margaret Olsen |
| Center for Advanced Cellular & Genetic Technology | The Center for Advanced Cellular & Genetic Technology consists of the Tissue Culture Support Center, the Induced Pluripotent Stem Cell Center and the Genome Engineering Center. We offer basic tissue culture services, generate, maintain and induce stem cell differentiation, and provide custom genome editing services. We also serve as a centralized general store offering more than 1500 commonly used lab consumables. | Teri Davidson |
| Center for Applied Research Sciences (CARS, ICTS) | The Center for Applied Research Sciences (CARS) has been established within the Institute of Clinical and Translational Sciences (ICTS) to increase access to specialized clinical research units where investigators can have access to state-of-the-art resources for conducting efficient, safe, and ethical studies in research volunteers. | icts@wustl.edu |
| Center for Biomedical Informatics (CBMI) | Software tools to facilitate biomedical research. These tools allow investigators to store, integrate, query, analyze, and visualize complex clinical and molecular data sets. The CBMI provides comprehensive training resources and facilitates collaborative studies for the identification of diagnostic and prognostic biomarkers and the subsequent development of personalized therapies. | Mary Uhlmansiek |
| Bioethics Research Center (BRC) | Education, consultation and research on topics of clinical research ethics | James DuBois |
| Center for Clinical Studies | The Center for Clinical Studies facilitates clinical research by supporting the effective evaluation of pharmaceuticals, medical devices and treatment outcomes and by providing administrative and clinical research services that move trials efficiently from initial proposal through study close-out. We assist with studies supported by federal and foundation grants and industry contracts, including strong support for investigator-initiated studies. | Teresa Arb |
| Center for Community Health Partnership & Research (CCHPR) | A joint center supported by the Washington University’s ICTS and the Institute for Public Health. The mission of the CCHPR is to reduce disparities and improve health and wellness in the St. Louis region by fostering bidirectional communication and supporting community-academic partnerships and research endeavors. | Hilary Broughton |
| Center for Health Economics and Policy (CHEP) | The Center for Health Economics and Policy encourages the development of evidence-based research focused on improving health and disseminates this work to policymakers and other stakeholders. | Leah Kemper |
| Central Neuroimaging Data Archive | Storage and analysis of MRI, PET, and CT imaging data | Dan Marcus |
| CIMED Live Cell Imaging Core (LCIF) | Live Cell Imaging Facility (LCIF) of the Center for Investigation of Membrane Excitability Diseases (CIMED) is focused on studying cell signaling in excitable cells with the use of optical live cell imaging methods. We provide instruments, expertise and assistance necessary to monitor cell functions, particularly intracellular ion concentrations, with the use of fluorescent indicators. | Kris Hyrc |
| Clinical & Translational Imaging Unit (formerly the Human Imaging Unit)(ICTS) | Advanced imaging technology, equipment and expertise to support basic and translational inpatient and outpatient clinical research | Pamela Woodard, Robert McKinstry |
| Clinical Research Training Center | Infrastructure to foster clinical research training and career development for predoctoral students, house-staff, postdoctoral fellows and faculty by integrating diverse training programs into a single location and administrative umbrella | crtc@email.wustl.edu |
| Clinical Translation Core (IDDRC) | (I) deliver genomic, phenomic, and environmental characterization of human subjects via its two primary units, the Human Genomic Characterization Unit (HGCU) and the Developmental and Behavioral Assessment Unit (DBAU); (II) support bidirectional exchange between exploration of individual variation and specific causal disease mechanisms; and (III) translate new knowledge of personalized medicine approaches into higher-impact interventions. | Christina Gurnett |
| Clinical Trials Unit (ICTS) | Research space, equipment, and nursing support for a wide range of clinical studies | Ann Doyle |
| Cytogenetics Core | Provides a comprehensive menu of cytogenetic tests for human and mouse tissues (for example mouse embryonic stem cells, cancer cell lines, skin, peripheral blood, buccal cells, bone marrow etc). | Jane Bauer |
| Developmental Neuroimaging Core (IDDRC) | high-quality comprehensive consultation for study design; highly cost-efficient data acquisition for IDDRC investigators collecting neuroimaging data in IDD research efforts; provide data processing, informatics, and analytic services that optimize the exploration and accurate interpretation of neuroimaging data in IDD research | Jeffrey Neil, Joshua Shimony |
| Digital Imaging Center | A joint resource of the Department of Pathology & Immunology and BJH. This Center specializes in digital imaging for clinical, teaching and research applications and is keeping up with advances in this fast moving area. | Brandy Gee |
| Dissemination & Implementation Research Core (DIRC) | Provides methodological expertise to advance translational (T2) research to inform and move efficacious health practices from clinical knowledge into routine, real-world use. | Elvin Geng, Ana Baumann |
| Electron Microscopy Facility (Dept of Pathology & Immunology) | Tissue processing and embedding, preparation of one micron thick toluidine blue stained sections and routine transmission electron microscopy for cell culture and tissue specimens. | Karen Green |
| Flow Cytometry & Fluorescence Activated Cell Sorting Core | Provides investigators with instrumentation and support for cell sorting as well as acquisition and analysis of flow cytometry data including: high speed cell sorting; assistance with experimental design; instruction and training on the instruments; consultations on sample preparation and data analysis | Erica Lantelme |
| Genome Center (GTAC): DNA and RNA Analysis | Genotyping and expression, all commercial microarray formats, custom array design and manufacture, RNA/DNA QC analysis, microarray processing and data analysis | Seth Crosby, Mike Heinz |
| Genome Center (GTAC): Next Generation Sequencing (NGS) | Mapping, whole genome sequencing, clone sequencing, sequence refinement, EST and cDNA sequencing | Lucinda Fulton |
| Genome Engineering and iPSC Center (GEiC) | Facilitating functional genomic studies through the use of patient-derived iPSCs and the generation of modified cells and organisms using genome editing technologies. | Xiaoxia Cui |
| Genome Technology Access Center (GTAC)@McDonnell Genome Institute (MGI) | Cutting-edge and cost effective sequencing and analysis technologies to local colleagues and external investigators. The GTAC offers fee-for-service sample preparation, data generation, bioinformatics analysis, and intellectual support for microarray, PCR, and high-throughput sequencing studies. | Richard Head |
| Hope Center Alafi Neuroimaging Core | Confocal and multiphoton microscopy; digital whole-slide scanning; atomic force microscopy | Kris Hyrc |
| Hope Center Animal Surgery Core | Models for stroke, traumatic brain injury | Ernie Gonzales |
| Hope Center DNA/RNA Purification Core | Offers nucleic acid extraction from a variety of sources including fresh or frozen whole blood, buffy coat, saliva, and frozen tissue and cell pellets. | Kristy Bergmann |
| Hope Center In Vivo Microdialysis Core | Screen compounds for their ability to reduce brain interstitial fluid (ISF) Aβ levels. Brain ISF can be sampled hourly in living mice using microdialysis. The technique not only determines the magnitude that a compound alters ISF Aβ, but also the kinetics of that change. | John Cirrito |
| Hope Center Microelectrode Array (MEA) | Useful for investigators interested in high-throughput screening of drug effects on excitability, disease-in-a-dish modeling, and other applications. | Tissue Culture Support Center (TCSC) |
| Hope Center Viral Vectors Core | Assist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment available | Mingjie Li |
| Human & Mouse Linked Evaluation of Tumors (HAMLET) Core | The mission is to promote understanding of the biology and genetics of Human Breast Cancer, and to provide better preclinical models for the validation of new treatment and imaging approaches. | Shunqiang Li |
| Hybridoma Center (WUHC) | Provides monoclonal antibody technology | Kathleen Sheehan |
| Immunomonitoring Laboratory (IML) | Providing the structure, instrumentation and expertise to monitor the impact of specific immunotherapies on human and mouse immunologic profiles, interrogate mechanisms and pathways related to treatment protocols and advance the conceptual basis for targeted treatment strategies. | Kathleen Sheehan Stephen Oh |
| Informatics Core Services (ICS) | Publicly accessible data resources, tools, references and protocols that will assist investigators in applying genomics to basic, translational and clinical cancer research; publicly accessible venue for “publishing” experimental findings and corresponding data sets generated from investigator-based studies | Albert Lai |
| Knight Alzheimer’s Disease Research Center Resources | Data and tissue from longitudinal studies | Krista Moulder |
| Metabolomics Facility | Metabolomic and lipidomic analysis of biological specimens; assay development for specific metabolites; high-throughput MS analysis for clinical studies | David Scherrer |
| mHealth Research Core | Network of researchers with a common interest in mHealth research, including the use of sensors, native or web-based apps, social media, and/or other smartphone technology to measure and improve health research and outcomes | Eric Lenze Ginger Nicol Katie Keenoy Stephanie Brown |
| Microbiological Media Services | The Microbiology Media Services Core Facility is fully staffed and equipped to provide complete services in hand poured, made-to-order microbiological media. The Media Services mission is to provide speedy and accurate products that enhance user confidence. | Matthew Williams |
| Model Systems Core (IDDRC) | Consultation to investigators needing assessments in animal behavior, pathology and CNS function; characterize neurological deficits in rodent and cellular models of IDD submitted by investigators; integrate information across units, cores and other existing facilities within the University | Karen O’Malley, Susan Maloney |
| Molecular Imaging Center | Provides assistance to investigators who have limited experience or resources by advice or direct help with experimental design and execution. The Core can clone and screen reporters and generate cell lines and transgenic or knock-in animals. Furthermore, MIRC can characterize reporter gene expression and molecular function using either radio-labeled or fluorescently tagged probes (together with the Chemistry Core) or through bioluminescence assays in vitro. Furthermore, the MIRC assists in planning and executing xenograft and transgenic studies in vivo. | |
| Mouse Genetics Core | Production and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivations | Mia Wallace |
| NIL Computational Core | Provides free training and/or advice on post-acquisition neuroimaging analyses for the Washington University neuroimaging community | nilcore@wustl.edu |
| Pediatric Disease Mouse Models Core (PDMMC) | Generate genetically altered mice for investigating mechanistic hypotheses relevant to the pathogenesis or treatment of genetically defined pediatric diseases | Jeff Miner |
| Pre-Clinical Imaging Facility | The primary purpose of the facility is to provide an infrastructure for investigators to perform qualitative and quantitative preclinical imaging positron emission tomography (PET) and computed tomography (CT) research to facilitate research and discovery of diagnostic and predictive imaging biomarkers of disease and validation of radiotracers for translation to the clinic. | Richard Laforest, PhD Kooresh Shoghi, PhD |
| Proteomics & Mass Spectrometry Program (PMSP) | Offers next generation mass spectrometry and data analysis tools for global and targeted protein quantification in biological fluids and tissues. | Reid Townsend |
| Proteomics Shared Resource) | Provides cancer center members with preferred access to current and innovative proteomics technologies for molecular profiling of clinical samples and for basic cancer research. | Reid Townsend Jim Malone |
| Recruitment Enhancement Core (REC) | A unique service that helps ICTS investigators meet and exceed study recruitment targets. The REC takes responsibility for enhancing recruitment; university wide, by passing a steady stream of qualified participants to the PIs and study coordinators. | Teresa Arb |
| Regulatory Support Center (ICTS) | Regulatory Core, Participant Advocacy and Ombudsman Core, and Recruitment Enhancement Core to assist in overcoming organizational barriers, navigating through regulatory requirements for human research, and recruiting adequate numbers of appropriate research participants for studies | Samuel Klein |
| Research Design & Biostatistics Group (RDBG) | Guides clinical study design, data collection and data analysis. Assistance is available from protocol/proposal preparation to manuscript development. | J. Philip Miller |
| RNAi Core | Viral vector-based RNAi technology to alter gene function in primary cultures | Brenda Theising |
| Siteman Biostatistics Shared Resource (SBSR) | Supporting consultation on biostatistics and epidemiology and cancer research through experimental designs, study monitoring and data analyses. | Graham Colditz, Rosy Luo |
| Siteman Flow Cytometry Core (SFC) | Services for flow cytometry-based cell analysis, cell sorting and flow cytometry instruction. The instrumentation includes six benchtop analyzers and four cell sorters. | Bill Eades |
| Small Animal Cancer Imaging (SACI) | Provides state-of-the-art facilities and infrastructure for MRI, PET, CT, Beta, SPECT, and optical imaging of mice, rats and other small laboratory animals that serve as models of cancer. | Joseph Ackerman Joel Garbow Richard Laforest Robert Massa |
| Tissue Procurement Core (ICTS) | Provides a centralized resource to collect, process, store, and utilize human biospecimens for translational and biomedical research. | Mark Watson, Brian Goetz |
| Transgenic, Knockout and Micro-Injection Core | Offers a wide array of mouse embryo manipulation techniques. We provide investigators a resource to generate mutant mouse models through a variety of techniques, cryopreserve mouse lines, cryopreservation/storage of mouse sperm, perform embryo rederivation, thaw embryos and perform IVF. | J. Michael White |
| Translational Cardiovascular Biobank & Repository (TCBR) | TCBR was founded for the acquisition (using standardized, validated procedures), utilization and storage of integrated human cardiovascular tissues and clinical data for detailed phenotypic (electrophysiological, structural, molecular and biochemical) and genotypic (genomic, epigenetic and somati c) analyses. | Evelyn Kanter |
| Washington University Center for Cellular Imaging (WUCCI) | State-of-the-art cellular imaging technologies; guidance in experimental design, sample prep, data analysis | Peter Bayguinov |
| Washing University Neuroimaging Community (WUNIC) | Informal consortium established to join together several groups of people across the WU campus – in the Med School, on the Main Campus, and beyond – that have a shared interest in neuroimaging. | |
| Washington University Pain Center | Behavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugs | Rob Gereau |
| Washington University Pediatric & Adolescent Ambulatory Research Consortium (WU PAARC) | WU PAARC has developed a formal infrastructure to actively engage community practitioners in clinical and translational research. WU PAARC initiates and conducts research studies and collaborates with other investigators to design and implement studies in the community setting. | Jane Garbutt |
| Washington University Gnotobiotic Core (WU-GREaT) | Germ-free and gnotobiotic mouse production [Gnotobiosis is a condition in which all the forms of life present within an mouse can be accounted for. This includes germ-free mice, as their microbial status (completely absent) is also known.] | Mike White |
