Access to equipment, expertise, reagents and other resources.  Click on the name of the facility for full descriptions. 

FacilityResources offeredContact
Anatomic and Molecular Pathology Core Lab (AMP)Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imagingCharles Eby
Animal Behavior CorePhenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholdsSusan Maloney, Carla Yuede
Biologic Therapy Core FacilityDevelops and manufactures novel biologic, cellular and other state-of-the-art therapeutics; labels MAB for use in Immuno-radiotherapy treatments or as PET imaging agents in oncological settings; routine tissue processing and cryopreservation; provides Research grade Lentiviral vectors; provides regulatory and administrative support in the therapeutic agent approval process.Todd Fehniger
Biology ImagingConfocal and deconvolution microscopyDianne Duncan
Biostatistics ConsultingDesign of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of dataKen Schechtman
Center for Administrative Data Research (CADR, ICTS)The Center for Administrative Data Research (CADR) serves to provide leadership and training in the use of health services administrative data in clinical epidemiologic, health services and outcomes research.Margaret Olsen
Center for Advanced Cellular & Genetic TechnologyThe Center for Advanced Cellular & Genetic Technology consists of the Tissue Culture Support Center, the Induced Pluripotent Stem Cell Center and the Genome Engineering Center.  We offer basic tissue culture services, generate, maintain and induce stem cell differentiation, and provide custom genome editing services.  We also serve as a centralized general store offering more than 1500 commonly used lab consumables.Teri Davidson
Center for Applied Research Sciences (CARS, ICTS)The Center for Applied Research Sciences (CARS) has been established within the Institute of Clinical and Translational Sciences (ICTS) to increase access to specialized clinical research units where investigators can have access to state-of-the-art resources for conducting efficient, safe, and ethical studies in research
Center for Biomedical Informatics (CBMI)Software tools to facilitate biomedical research. These tools allow investigators to store, integrate, query, analyze, and visualize complex clinical and molecular data sets. The CBMI provides comprehensive training resources and facilitates collaborative studies for the identification of diagnostic and prognostic biomarkers and the subsequent development of personalized therapies.Mary Uhlmansiek
Bioethics Research Center (BRC)Education, consultation and research on topics of clinical research ethicsJames DuBois
Center for Clinical StudiesThe Center for Clinical Studies facilitates clinical research by supporting the effective evaluation of pharmaceuticals, medical devices and treatment outcomes and by providing administrative and clinical research services that move trials efficiently from initial proposal through study close-out. We assist with studies supported by federal and foundation grants and industry contracts, including strong support for investigator-initiated studies.Teresa Arb
Center for Community Health Partnership & Research (CCHPR) A joint center supported by the Washington University’s ICTS and the Institute for Public Health.  The mission of the CCHPR is to reduce disparities and improve health and wellness in the St. Louis region by fostering bidirectional communication and supporting community-academic partnerships and research endeavors.Hilary Broughton
Center for Health Economics and Policy (CHEP)The Center for Health Economics and Policy encourages the development of evidence-based research focused on improving health and disseminates this work to policymakers and other stakeholders.Leah Kemper
Central Neuroimaging Data ArchiveStorage and analysis of MRI, PET, and CT imaging dataDan Marcus
CIMED Live Cell Imaging Core (LCIF)Live Cell Imaging Facility (LCIF) of the Center for Investigation of Membrane Excitability Diseases (CIMED) is focused on studying cell signaling in excitable cells with the use of optical live cell imaging methods. We provide instruments, expertise and assistance necessary to monitor cell functions, particularly intracellular ion concentrations, with the use of fluorescent indicators.Kris Hyrc
Clinical & Translational Imaging Unit (formerly the Human Imaging Unit)(ICTS)Advanced imaging technology, equipment and expertise to support basic and translational inpatient and outpatient clinical researchPamela Woodard, Robert McKinstry
Clinical Research Training CenterInfrastructure to foster clinical research training and career development for predoctoral students, house-staff, postdoctoral fellows and faculty by integrating diverse training programs into a single location and administrative
Clinical Translation Core (IDDRC)(I) deliver genomic, phenomic, and environmental characterization of human subjects via its two primary units, the Human Genomic Characterization Unit (HGCU) and the Developmental and Behavioral Assessment Unit (DBAU); (II) support bidirectional exchange between exploration of individual variation and specific causal disease mechanisms; and (III) translate new knowledge of personalized medicine approaches into higher-impact interventions.Christina Gurnett
Clinical Trials Unit (ICTS)Research space, equipment, and nursing support for a wide range of clinical studiesAnn Doyle
Cytogenetics CoreProvides a comprehensive menu of cytogenetic tests for human and mouse tissues (for example mouse embryonic stem cells, cancer cell lines, skin, peripheral blood, buccal cells, bone marrow etc).Jane Bauer
Developmental Neuroimaging Core (IDDRC)high-quality comprehensive consultation for study design; highly cost-efficient data acquisition for IDDRC investigators collecting neuroimaging data in IDD research efforts; provide data processing, informatics, and analytic services that optimize the exploration and accurate interpretation of neuroimaging data in IDD researchJeffrey Neil, Joshua Shimony
Digital Imaging CenterA joint resource of the Department of Pathology & Immunology and BJH. This Center specializes in digital imaging for clinical, teaching and research applications and is keeping up with advances in this fast moving area.Brandy Gee
Dissemination & Implementation Research Core (DIRC)Provides methodological expertise to advance translational (T2) research to inform and move efficacious health practices from clinical knowledge into routine, real-world use.Elvin Geng, Ana Baumann
Electron Microscopy Facility (Dept of Pathology & Immunology)Tissue processing and embedding, preparation of one micron thick toluidine blue stained sections and routine transmission electron microscopy for cell culture and tissue specimens.Karen Green
Flow Cytometry & Fluorescence Activated Cell Sorting CoreProvides investigators with instrumentation and support for cell sorting as well as acquisition and analysis of flow cytometry data including: high speed cell sorting; assistance with experimental design; instruction and training on the instruments; consultations on sample preparation and data analysisErica Lantelme
Genome Center (GTAC): DNA and RNA AnalysisGenotyping and expression, all commercial microarray formats, custom array design and manufacture, RNA/DNA QC analysis, microarray processing and data analysisSeth CrosbyMike Heinz
Genome Center (GTAC): Next Generation Sequencing (NGS)Mapping, whole genome sequencing, clone sequencing, sequence refinement, EST and cDNA sequencingLucinda Fulton
Genome Engineering and iPSC Center (GEiC)Facilitating functional genomic studies through the use of patient-derived iPSCs and the generation of modified cells and organisms using genome editing technologies.Xiaoxia Cui
Genome Technology Access Center (GTAC)@McDonnell Genome Institute (MGI)Cutting-edge and cost effective sequencing and analysis technologies to local colleagues and external investigators. The GTAC offers fee-for-service sample preparation, data generation, bioinformatics analysis, and intellectual support for microarray, PCR, and high-throughput sequencing studies.Richard Head
Hope Center Alafi Neuroimaging CoreConfocal and multiphoton microscopy; digital whole-slide scanning; atomic force microscopyKris Hyrc
Hope Center Animal Surgery CoreModels for stroke, traumatic brain injuryErnie Gonzales
Hope Center DNA/RNA Purification CoreOffers nucleic acid extraction from a variety of sources including fresh or frozen whole blood, buffy coat, saliva, and frozen tissue and cell pellets.Kristy Bergmann
Hope Center In Vivo Microdialysis CoreScreen compounds for their ability to reduce brain interstitial fluid (ISF) Aβ levels.  Brain ISF can be sampled hourly in living mice using microdialysis.  The technique not only determines the magnitude that a compound alters ISF Aβ, but also the kinetics of that change.John Cirrito
Hope Center Microelectrode Array (MEA)Useful for investigators interested in high-throughput screening of drug effects on excitability, disease-in-a-dish modeling, and other applications.Tissue Culture Support Center (TCSC)
Hope Center Viral Vectors CoreAssist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment availableMingjie Li
Human & Mouse Linked Evaluation of Tumors (HAMLET) CoreThe mission is to promote understanding of the biology and genetics of Human Breast Cancer, and to provide better preclinical models for the validation of new treatment and imaging approaches.Shunqiang Li
Hybridoma Center (WUHC)Provides monoclonal antibody technologyKathleen Sheehan
Immunomonitoring Laboratory (IML)Providing the structure, instrumentation and expertise to monitor the impact of specific immunotherapies on human and mouse immunologic profiles, interrogate mechanisms and pathways related to treatment protocols and advance the conceptual basis for targeted treatment strategies.Kathleen Sheehan
Stephen Oh
Informatics Core Services (ICS)Publicly accessible data resources, tools, references and protocols that will assist investigators in applying genomics to basic, translational and clinical cancer research; publicly accessible venue for “publishing” experimental findings and corresponding data sets generated from investigator-based studiesAlbert Lai
Knight Alzheimer’s Disease Research Center ResourcesData and tissue from longitudinal studiesKrista Moulder
Metabolomics FacilityMetabolomic and lipidomic analysis of biological specimens; assay development for specific metabolites; high-throughput MS analysis for clinical studiesDavid Scherrer
mHealth Research CoreNetwork of researchers with a common interest in mHealth research, including the use of sensors, native or web-based apps, social media, and/or other smartphone technology to measure and improve health research and outcomesEric Lenze
Ginger Nicol
Katie Keenoy
Stephanie Brown
Microbiological Media ServicesThe Microbiology Media Services Core Facility is fully staffed and equipped to provide complete services in hand poured, made-to-order microbiological media. The Media Services mission is to provide speedy and accurate products that enhance user confidence.Matthew Williams
Model Systems Core (IDDRC)Consultation to investigators needing assessments in animal behavior, pathology and CNS function; characterize neurological deficits in rodent and cellular models of IDD submitted by investigators; integrate information across units, cores and other existing facilities within the UniversityKaren O’Malley, Susan Maloney
Molecular Imaging CenterProvides assistance to investigators who have limited experience or resources by advice or direct help with experimental design and execution. The Core can clone and screen reporters and generate cell lines and transgenic or knock-in animals. Furthermore, MIRC can characterize reporter gene expression and molecular function using either radio-labeled or fluorescently tagged probes (together with the Chemistry Core) or through bioluminescence assays in vitro. Furthermore, the MIRC assists in planning and executing xenograft and transgenic studies in vivo.

Julie Prior, Katie Duncan

Mouse Genetics CoreProduction and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivationsMia Wallace
NIL Computational CoreProvides free training and/or advice on post-acquisition neuroimaging analyses for the Washington University neuroimaging
Pediatric Disease Mouse Models Core (PDMMC)Generate genetically altered mice for investigating mechanistic hypotheses relevant to the pathogenesis or treatment of genetically defined pediatric diseasesJeff Miner
Pre-Clinical Imaging FacilityThe primary purpose of the facility is to provide an infrastructure for investigators to perform qualitative and quantitative preclinical imaging positron emission tomography (PET) and computed tomography (CT) research to facilitate research and discovery of diagnostic and predictive imaging biomarkers of disease and validation of radiotracers for translation to the clinic.Richard Laforest, PhD
Kooresh Shoghi, PhD
Proteomics & Mass Spectrometry Program (PMSP)Offers next generation mass spectrometry and data analysis tools for global and targeted protein quantification in biological fluids and tissues.Reid Townsend
Proteomics Shared Resource)Provides cancer center members with preferred access to current and innovative proteomics technologies for molecular profiling of clinical samples and for basic cancer research.Reid Townsend
Jim Malone
Recruitment Enhancement Core (REC)A unique service that helps ICTS investigators meet and exceed study recruitment targets. The REC takes responsibility for enhancing recruitment; university wide, by passing a steady stream of qualified participants to the PIs and study coordinators.Teresa Arb
Regulatory Support Center (ICTS)Regulatory Core, Participant Advocacy and Ombudsman Core, and Recruitment Enhancement Core to assist in overcoming organizational barriers, navigating through regulatory requirements for human research, and recruiting adequate numbers of appropriate research participants for studiesSamuel Klein
Research Design & Biostatistics Group (RDBG)Guides clinical study design, data collection and data analysis. Assistance is available from protocol/proposal preparation to manuscript development.J. Philip Miller
RNAi CoreViral vector-based RNAi technology to alter gene function in primary culturesBrenda Theising
Siteman Biostatistics Shared Resource (SBSR)Supporting consultation on biostatistics and epidemiology and cancer research through experimental designs, study monitoring and data analyses.Graham Colditz,
Rosy Luo
Siteman Flow Cytometry Core (SFC)Services for flow cytometry-based cell analysis, cell sorting and flow cytometry instruction. The instrumentation includes six benchtop analyzers and four cell sorters.Bill Eades
Small Animal Cancer Imaging (SACI)Provides state-of-the-art facilities and infrastructure for MRI, PET, CT, Beta, SPECT, and optical imaging of mice, rats and other small laboratory animals that serve as models of cancer.Joseph Ackerman
Joel Garbow
Richard Laforest
Robert Massa
Tissue Procurement Core (ICTS)Provides a centralized resource to collect, process, store, and utilize human biospecimens for translational and biomedical research.Mark Watson, Brian Goetz
Transgenic, Knockout and Micro-Injection CoreOffers a wide array of mouse embryo manipulation techniques. We provide investigators a resource to generate mutant mouse models through a variety of techniques, cryopreserve mouse lines, cryopreservation/storage of mouse sperm, perform embryo rederivation, thaw embryos and perform IVF.J. Michael White
Translational Cardiovascular Biobank & Repository (TCBR)TCBR was founded for the acquisition (using standardized, validated procedures), utilization and storage of integrated human cardiovascular tissues and clinical data for detailed phenotypic (electrophysiological, structural, molecular and biochemical) and genotypic (genomic, epigenetic and somati c) analyses.Evelyn Kanter
Washington University Center for Cellular Imaging  (WUCCI)State-of-the-art cellular imaging technologies; guidance in experimental design, sample prep, data analysisPeter Bayguinov
Washing University Neuroimaging Community (WUNIC)Informal consortium established to join together several groups of people across the WU campus – in the Med School, on the Main Campus, and beyond – that have a shared interest in neuroimaging.

Beth Beato

Washington University Pain CenterBehavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugsRob Gereau
Washington University Pediatric & Adolescent Ambulatory Research Consortium (WU PAARC)WU PAARC has developed a formal infrastructure to actively engage community practitioners in clinical and translational research. WU PAARC initiates and conducts research studies and collaborates with other investigators to design and implement studies in the community setting.Jane Garbutt
Washington University Gnotobiotic Core (WU-GREaT)Germ-free and gnotobiotic mouse production [Gnotobiosis is a condition in which all the forms of life present within an mouse can be accounted for. This includes germ-free mice, as their microbial status (completely absent) is also known.]Mike White