Anti-aging compound that improves metabolic health in mice improves muscle glucose metabolism in people

A natural compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice has clinically relevant effects in people, according to new research at Washington University School of Medicine in St. Louis. A small clinical trial of postmenopausal women with prediabetes shows that the compound NMN (nicotinamide mononucleotide) improved the ability of […]

Aging delayed in older mice given blood component from young mice

New research has identified a novel approach to staving off the detrimental effects of aging, according to a study from Washington University School of Medicine in St. Louis. The study suggests that a protein that is abundant in the blood of young mice plays a vital role in keeping mice healthy. With age, levels of […]

Imai awarded $1.6M from NIH’s National Institute on Aging

Shin-ichiro Imai, MD, PhD, professor of developmental biology at the School of Medicine, received a five-year, $1.6 million grant from the National Institute on Aging of the National Institutes of Health (NIH) for his project titled “eNAMPT-mediated adipo-hypothalamic communication for NAD+ production and aging.” Read more.

Scientists identify new fuel-delivery route for cells

Findings shed light on chronic diseases, aging From the WashU School of Medicine News… Scientists at Washington University School of Medicine in St. Louis have identified a previously unknown route for cellular fuel delivery, a finding that could shed light on the process of aging and the chronic diseases that often accompany it. With age, […]