WashU weekly Neuroscience publications

“Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains” (2022) Molecular Neurodegeneration Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains(2022) Molecular Neurodegeneration, 17 (1), art. no. 10, .  Bigley, T.M.a , Xiong, M.b c d , Ali, M.f , Chen, Y.b c e , Wang, C.b , Serrano, J.R.b , Eteleeb, A.f g , Harari, O.b f g , […]

Herzog to test how cortical neurons, hormones regulate daily patterns of behavior

Circadian rhythms are physical, mental and behavioral changes that follow a 24-hour cycle. Research from Washington University in St. Louis will test how these daily patterns are set and maintained through the coordinated activity of certain neurons and hormones. The five-year $1.98 million project relies on new high-throughput machine learning techniques to determine the roles […]

Zacks’ talk ties movies to neuroscience

Jeffrey Zacks, PhD, professor and associate chair of psychological and brain sciences in Arts & Sciences at Washington University in St. Louis, will explain how and why television and movies can have such strong effects on our brains in a Mirowitz Center online program, co-sponsored with St. Louis NORC and the St. Louis Jewish Film Festival.  The Zoom event, which […]

AAAS names eight Washington University faculty as 2021 fellows

Eight faculty members at Washington University in St. Louis are among 564 new fellows selected by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the Science family of journals. Arts & Sciences’ Leonard Green, PhD, Elizabeth S. Haswell, PhD, Sophia E. Hayes, PhD, Erik Herzog, PhD, Mark A. McDaniel, PhD, Jay W. Ponder, PhD and Crickette […]

WashU weekly Neuroscience publications

“Plasma MCP-1 and changes on cognitive function in community-dwelling older adults” (2022) Alzheimer’s Research and Therapy Plasma MCP-1 and changes on cognitive function in community-dwelling older adults(2022) Alzheimer’s Research and Therapy, 14 (1), art. no. 5, .  Sanchez-Sanchez, J.L.a b , Giudici, K.V.a , Guyonnet, S.a c , Delrieu, J.a c , Li, Y.d e , Bateman, R.J.d e f g , Parini, A.h , Vellas, B.a c , de Souto Barreto, P.a c , Vellas, B.i , Guyonnet, S.i , Carrié, […]

WashU weekly Neuroscience publications

“Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients” (2022) Molecular Neurodegeneration Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients(2022) Molecular Neurodegeneration, 17 (1), art. no. 1, .  Bloom, A.J.a , Mao, X.a , Strickland, A.a , Sasaki, Y.a , Milbrandt, J.a , DiAntonio, A.b a Needleman Center for Neurometabolism and Axonal Therapeutics and Department of Genetics, Washington University School […]

WashU weekly Neuroscience publications

“Electroconvulsive therapy in treatment resistant depression” (2022) Journal of the Neurological Sciences Electroconvulsive therapy in treatment resistant depression(2022) Journal of the Neurological Sciences, 434, art. no. 120095, .  Subramanian, S.a b , Lopez, R.a b , Zorumski, C.F.a b , Cristancho, P.a b a Department of Psychiatry, Washington University in St Louis School of Medicine, St Louis, MO, United Statesb Department of Psychiatry, University of Texas Rio Grande Valley […]

WashU weekly Neuroscience publications

“Filtering respiratory motion artifact from resting state fMRI data in infant and toddler populations” (2022) NeuroImage Filtering respiratory motion artifact from resting state fMRI data in infant and toddler populations(2022) NeuroImage, 247, art. no. 118838, .  Kaplan, S.a , Meyer, D.a , Miranda-Dominguez, O.g h , Perrone, A.f j , Earl, E.h j , Alexopoulos, D.a , Barch, D.M.b d e , Day, T.K.M.f , Dust, J.a , Eggebrecht, A.T.b , Feczko, E.g h , Kardan, O.k , […]

WashU weekly Neuroscience publications

“Psychometric properties of the Peceived Benefits of Thinness Scale in college-aged women” (2022) Body Image Psychometric properties of the Peceived Benefits of Thinness Scale in college-aged women(2022) Body Image, 40, pp. 103-109.  Flatt, R.E.a , Karam, A.M.b , Fitzsimmons-Craft, E.E.b , Balantekin, K.N.c , Graham, A.K.d , Eichen, D.M.e , Monterubio, G.E.b , Goel, N.J.f , Fowler, L.A.b , Sadeh-Sharvit, S.g h i , Wilfley, D.b , Mazina, V.j k , Taylor, C.B.g h , Trockel, […]

WashU weekly Neuroscience publications

“Automated sleep state classification of wide-field calcium imaging data via multiplex visibility graphs and deep learning” (2022) Journal of Neuroscience Methods Automated sleep state classification of wide-field calcium imaging data via multiplex visibility graphs and deep learning(2022) Journal of Neuroscience Methods, 366, art. no. 109421, .  Zhang, X.a , Landsness, E.C.b , Chen, W.b , Miao, H.b , Tang, M.b , Brier, L.M.c , Culver, J.P.c d e f , Lee, […]

Paola Cepeda named Director of Postdoctoral Affairs

Dear Colleagues, I am pleased to announce that, after a nationwide search, Paola Cepeda, PhD, has been named Director of Postdoctoral Affairs in the Office of the Vice Chancellor for Research, effective January 4, 2022. Paola currently serves as the Program Manager for Graduate and Postdoctoral Professional Development at Stony Brook University. In the role […]

How do others help us regulate emotions?

When COVID-19 hit, many people were suddenly cut off from their social support systems, the people with whom we often share our emotional lives. They who listen to our grievances, share in our happiness, or just sit there, being bored with us. Is that a problem? How much do we depend on others to help […]

WashU weekly Neuroscience publications

“Levetiracetam Prophylaxis for Children Admitted With Traumatic Brain Injury” (2022) Pediatric Neurology Levetiracetam Prophylaxis for Children Admitted With Traumatic Brain Injury (2022) Pediatric Neurology, 126, pp. 114-119.  Surtees, T.-L.a , Kumar, I.b , Garton, H.J.L.c , Rivas-Rodriguez, F.d , Parmar, H.d , McCaffery, H.b , Riebe-Rodgers, J.b , Shellhaas, R.A.b a Department of Neurology, Washington University in St. Louis School of Medicine, St. Louis, MO, United Statesb Departments […]

Which mask is easier on the ears?

To assess how different styles of face masks affected speech intelligibility in normal hearing listeners, researchers from Washington University in St. Louis put some of the most popular mask designs to the test. Their research was published in the journal Cognitive Research: Principles and Implications. The team, from the labs of Kristin Van Engen, PhD, assistant professor […]

It’s complicated: Social media and well-being during COVID-19

When students were told to stay home after COVID-19 began to spread stateside, it’s not surprising that their social media use increased — there wasn’t much else to do. But was it all doom scrolling and catastrophizing or was social media living up to its promise to keep people connected and strengthen our ties to […]

Minton appointed vice chancellor for technology and chief information officer

Jessie Minton, vice provost and chief information officer at the University of Oregon, has been appointed vice chancellor for technology and chief information officer at Washington University in St. Louis, effective April 15, according to Shantay Bolton, executive vice chancellor and chief administrative officer. Minton will succeed Stephanie L. Reel, who has served as interim chief […]

Persistent, distressing psychotic-like experiences associated with impairment in youth

In a new study from the lab of Deanna Barch, PhD, professor and chair of psychological and brain sciences in Arts & Sciences, and the Gregory B. Couch Professor of Psychiatry and of radiology at the School of Medicine, all at Washington University in St. Louis, researchers examined the association between distressing and persistent psychotic-like experiences […]

WashU weekly Neuroscience publications

“Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes” (2022) Medical Image Analysis Multi-scale semi-supervised clustering of brain images: Deriving disease subtypes(2022) Medical Image Analysis, 75, art. no. 102304, .  Wen, J.a , Varol, E.b , Sotiras, A.c , Yang, Z.a , Chand, G.B.d , Erus, G.a , Shou, H.a e , Abdulkadir, A.a , Hwang, G.a , Dwyer, D.B.f , Pigoni, A.g , Dazzan, P.h , Kahn, R.S.i , Schnack, H.G.j , Zanetti, M.V.k , […]

Prenatal, early-life influences on child brain development focus of new study

Researchers at Washington University School of Medicine in St. Louis are joining scientists at 24 other sites around the country to conduct a comprehensive study aimed at understanding how prenatal factors and early life experiences influence brain development and behavior in infants and young children. With more than $37 million in funding from several institutes […]

WashU weekly Neuroscience publications

“Personalized networks of social anxiety disorder and depression and implications for treatment” (2022) Journal of Affective Disorders Personalized networks of social anxiety disorder and depression and implications for treatment(2022) Journal of Affective Disorders, 298, pp. 262-276.  Piccirillo, M.L., Rodebaugh, T.L. Department of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63130, United States AbstractIntroduction: Social […]

Irene Antony on her Society for Neuroscience Award, and the importance of undergraduate mentorship at WashU

Irene Antony, a neuroscience major in the School of Arts & Sciences at Washington University in St. Louis, won the Trainee Professional Development Award (TPDA) from the Society for Neuroscience (SfN). The TPDA is awarded from a common pool of undergraduates, graduate students, and postdoctoral fellows who demonstrate scientific merit and excellence in research. Recipients […]

Lodge to depart Washington University

Jennifer K. Lodge, PhD, vice chancellor for research at Washington University in St. Louis and the David T. Blasingame Professor, will leave the university at the end of the year. Lodge will be joining Duke University as vice president for research and innovation in January. “Dr. Lodge has served Washington University during extraordinary times, providing […]

WashU weekly Neuroscience publications

“Semaphorin-Plexin Signaling: From Axonal Guidance to a New X-Linked Intellectual Disability Syndrome” (2022) Pediatric Neurology Semaphorin-Plexin Signaling: From Axonal Guidance to a New X-Linked Intellectual Disability Syndrome(2022) Pediatric Neurology, 126, pp. 65-73.  Steele, J.L.a , Morrow, M.M.b , Sarnat, H.B.c , Alkhunaizi, E.d , Brandt, T.b , Chitayat, D.A.d , DeFilippo, C.P.e , Douglas, G.V.b , Dubbs, H.A.f , Elloumi, H.Z.b , Glassford, M.R.g , Hannibal, M.C.g , Héron, B.h , Kim, […]

WashU weekly Neuroscience publications

“Contribution of animal models toward understanding resting state functional connectivity” (2021) NeuroImage Contribution of animal models toward understanding resting state functional connectivity(2021) NeuroImage, 245, art. no. 118630, .  Pais-Roldán, P.a , Mateo, C.b , Pan, W.-J.c , Acland, B.d , Kleinfeld, D.b e , Snyder, L.H.d , Yu, X.f , Keilholz, S.c a Medical Imaging Physics, Institute of Neuroscience and Medicine 4, Forschungszentrum Jülich52425, Germanyb Department of Physics, University of […]

WashU weekly Neuroscience publications

“The relationship between diffusion heterogeneity and microstructural changes in high-grade gliomas using Monte Carlo simulations” (2022) Magnetic Resonance Imaging The relationship between diffusion heterogeneity and microstructural changes in high-grade gliomas using Monte Carlo simulations(2022) Magnetic Resonance Imaging, 85, pp. 108-120.  Lee, C.-Y.a , Bennett, K.M.b , Debbins, J.P.c , Choi, I.-Y.a d e f , Lee, P.a e f a Hoglund Biomedical Imaging Center, University of Kansas Medical Center, […]

$15 million gift to strengthen life science education, research across university

A decades-long friendship and a shared passion for basic science has inspired a $15 million gift to the Division of Biology & Biomedical Sciences (DBBS) at Washington University in St. Louis to fund undergraduate programs and graduate student fellowships in the life sciences. DBBS’ founding director, P. Roy Vagelos, MD, and his wife, Diana Vagelos, […]

More sleep leads to better grades and well-being

Want good grades? Get a good semester’s sleep. But good sleep, it turns out, is not just about quantity. It’s also about consistency. Research from Tim Bono, PhD, lecturer in psychological and brain sciences in Arts & Sciences at Washington University in St. Louis, found that students who get a good night’s sleep night in […]

WashU Expert: Time to retire daylight saving time

Change is upon us once again. Come the first Sunday of November, we will gain an hour of morning sunlight. The one-hour adjustment to the clock on the wall may not sound dramatic. But our biological clock begs to differ. Take, for example, the members of society blissfully unaware of social time: our youngest children […]

WashU weekly Neuroscience publications

“Equivalent learning, but unequal participation: Male bumble bees learn comparably to females, but participate in cognitive assessments at lower rates” (2021) Behavioural Processes Equivalent learning, but unequal participation: Male bumble bees learn comparably to females, but participate in cognitive assessments at lower rates (2021) Behavioural Processes, 193, art. no. 104528, . Manning, T.H.a b , Austin, M.W.a b c , MuseMorris, K.a , Dunlap, A.S.a b  a Department […]

Psychotic experiences in children predict genetic risk for mental disorders

So much has happened in the world to cause people to think deeper about their mental well-being and resiliency during difficult times. More than 50% of the population has struggled with a mental health issue at some point in their lives. They can be as disabling as physical conditions and are among the leading causes […]

WashU weekly Neuroscience publications

“Circadian neurons in the paraventricular nucleus entrain and sustain daily rhythms in glucocorticoids” (2021) Nature Communications Circadian neurons in the paraventricular nucleus entrain and sustain daily rhythms in glucocorticoids (2021) Nature Communications, 12 (1), art. no. 5763, .  Jones, J.R.a b , Chaturvedi, S.a , Granados-Fuentes, D.a , Herzog, E.D.a a Department of Biology, Washington University, St. Louis, St. Louis, MO, United States b Department of Biology, Texas […]

WashU weekly Neuroscience publications

“Spectral signature of attentional reorienting in the human brain” (2021) NeuroImage Spectral signature of attentional reorienting in the human brain (2021) NeuroImage, 244, art. no. 118616, .  Spadone, S.a , Betti, V.b c , Sestieri, C.a , Pizzella, V.a , Corbetta, M.d e f , Della Penna, S.a a Department of Neuroscience, Imaging and Clinical Sciences – and ITAB, Institute for Advanced Biomedical Technologies, G. d’Annunzio University of Chieti-Pescara, […]

WashU weekly Neuroscience publications

“A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging” (2021) Journal of Biomechanics A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging (2021) Journal of Biomechanics, 129, art. […]

‘Fight or flight’ – unless internal clocks are disrupted, study in mice shows

For humans and animals, many aspects of normal behavior and physiology rely on the proper functioning of the body’s circadian clocks. Here’s how it’s supposed to work: Your brain sends signals to your body to release different hormones at certain times of the day. For example, you get a boost of the hormone cortisol — nature’s […]

WashU weekly Neuroscience publications

“A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging” (2021) Journal of Biomechanics A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging (2021) Journal of Biomechanics, 129, art. […]

McDonnell Foundation awards Roediger $750,000 for memory research

The James S. McDonnell Foundation has awarded $750,000 to Henry “Roddy” Roediger, the James S. McDonnell Distinguished University Professor of Psychological & Brain Sciences in Arts & Sciences at Washington University in St. Louis. The three-year award will fund the Collective Memory Collaborative, led by Roediger and co-principal investigator James Wertsch, the David R. Francis Distinguished Professor in anthropology […]

WashU weekly Neuroscience publications

“Is comprehensiveness critical? Comparing short and long format cognitive assessments in preclinical Alzheimer disease” (2021) Alzheimer’s Research and Therapy Is comprehensiveness critical? Comparing short and long format cognitive assessments in preclinical Alzheimer disease (2021) Alzheimer’s Research and Therapy, 13 (1), art. no. 153, .  Hassenstab, J.a b , Nicosia, J.a , LaRose, M.a , Aschenbrenner, A.J.a , Gordon, B.A.b c , Benzinger, T.L.S.c , Xiong, C.a d , Morris, J.C.a a Charles F. and […]

WashU weekly Neuroscience publications

“Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases” (2022) Neural Regeneration Research Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases (2022) Neural Regeneration Research, 17 (4), pp. 867-874.  Li, H., Knight, W., Xu, J. Department of Radiology, Washington University School of Medicine, St. Louis, […]

Who’s in cognitive control?

Are you able to start a task and stick with it, all the way through, ignoring the temptations of the internet or the sudden realization that you should probably do the laundry? Or maybe you should be doing something else right this moment? The faculty that allows people to make plans or goals, and carry […]

Sabin Nettles receives SfN Next Generation Award

Sabin Nettles, a neuroscience PhD student in the laboratory of Dr. Harrison Gabel, is the recipient of the Pre-/ Post-Doctoral Next Generation Award from the Society for Neuroscience (SfN). The Next Generation Award recognizes SfN chapter members who have made outstanding contributions to public communication, outreach, and education about neuroscience through activities such as classroom […]

WashU weekly Neuroscience publications

“The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons” (2021) Cell and Bioscience The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons (2021) Cell and Bioscience, 11 (1), art. no. 167, .  Zhang, Y.a b f , Ma, S.a b , Ke, X.a b , Yi, Y.a b , Yu, H.a b , Yu, D.a b , Li, Q.c , Shang, Y.b d , Lu, […]

The science of living with purpose

Patrick Hill investigates the effects of living purposefully on health, wealth, and wellness – and how to maintain one’s purpose through life’s transitions. Whether you spend your weekdays as an employee, retiree, caretaker, student, or something else entirely, a typical morning likely includes some familiar components. Wake up, perhaps have a cup of coffee, and […]

WashU weekly Neuroscience publications

"A machine learning approach for the factorization of psychometric data with application to the Delis Kaplan Executive Function System" (2021) Scientific Reports A machine learning approach for the factorization of psychometric data with application to the Delis Kaplan Executive Function System(2021) Scientific Reports, 11 (1), art. no. 16896, .  Camilleri, J.A.a b , Eickhoff, S.B.a b , Weis, S.a b , Chen, J.a b c , Amunts, J.a b , Sotiras, A.d , […]

Neurons in visual cortex of the brain ‘drift’ over time

Although other studies have documented “representational drift” in neurons in the parts of the brain associated with odor and spatial memory, this result is surprising because neural activity in the primary visual cortex is thought to be relatively stable. The study published Aug. 27 in Nature Communications was led by Ji Xia, PhD, a recent PhD graduate of […]

WashU weekly Neuroscience publications

“Basal ganglia shape features differentiate schizoaffective disorder from schizophrenia” (2021) Psychiatry Research – Neuroimaging Basal ganglia shape features differentiate schizoaffective disorder from schizophrenia (2021) Psychiatry Research – Neuroimaging, 317, art. no. 111352, .  Cobia, D.a e , Rich, C.b , Smith, M.J.c , Mamah, D.d , Csernansky, J.G.e , Wang, L.e f g a Department of Psychology and Neuroscience Center, Brigham Young University, 1036 KMBL, Provo, UT 84602, United […]

Brain trust: Symposium brings together diverse community of undergraduate neuroscientists

The WUSTL ENDURE program, which hosts the annual symposium, partners with groups across WashU and local institutions to attract top talent, provide training and mentorship opportunities, and improve the diversity of the neuroscience field. “What would happen if you lost your heart?” Ephraim Oyetunji, a rising junior studying neuroscience in the Department of Biology and […]

Cannabis use disorder: another COVID risk factor

Should doctors take particular care to talk to patients about the potential dangers of COVID-19 if those patients have a problematic relationship with pot? New research from Washington University in St. Louis suggests perhaps they should. Diabetes, obesity and a history of smoking cigarettes are all considered risk factors for poorer COVID-19 outcomes. Warnings and […]

WashU weekly Neuroscience publications

“Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice” (2021) Communications Biology Long range synchronization within the enteric nervous system underlies propulsion along the large intestine in mice (2021) Communications Biology, 4 (1), art. no. 955, .  Spencer, N.J.a , Travis, L.a , Wiklendt, L.b , Costa, M.a , Hibberd, T.J.a , Brookes, S.J.a , Dinning, P.b , Hu, H.c , Wattchow, […]

17-year study of children associates poverty with smaller, slower-growing subcortical regions

Children in poverty are more likely to have cognitive and behavioral difficulties than their better-off peers. Plenty of past research has looked into the physical effects of childhood poverty, or documented mental health disparities between socioeconomic classes. But Deanna Barch, chair and professor in the Department of Psychological & Brain Sciences in Arts & Sciences at […]

WashU weekly Neuroscience publications

"Chronic neuroleptic treatment combined with a high fat diet elevated (3H) flunitrazepam binding in the cerebellum (2022) Progress in Neuro-Psychopharmacology and Biological Psychiatry Chronic neuroleptic treatment combined with a high fat diet elevated [3H] flunitrazepam binding in the cerebellum(2022) Progress in Neuro-Psychopharmacology and Biological Psychiatry, 112, art. no. 110407, .  Richardson, B.a b , Swenson, S.a , Hamilton, J.a b , Leonard, K.c , Delis, F.d , […]