WashU weekly Neuroscience publications

“Dynamic contrast enhancement and flexible odor codes” (2018) Nature Communications Dynamic contrast enhancement and flexible odor codes (2018) Nature Communications, 9 (1), art. no. 3062, .  Nizampatnam, S.a b , Saha, D.a , Chandak, R.a , Raman, B.a b a Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, United States b Department of Electrical and Systems Engineering, Washington University in […]

WashU weekly Neuroscience publications

“Matrine inhibits itching by lowering the activity of calcium channel” (2018) Scientific Reports Matrine inhibits itching by lowering the activity of calcium channel (2018) Scientific Reports, 8 (1), art. no. 11328, .  Geng, X.a , Shi, H.a , Ye, F.a , Du, H.b , Qian, L.a , Gu, L.a , Wu, G.a , Zhu, C.a , Yang, Y.a , Wang, C.a […]

A path to diversity in neuroscience

ENDURE fosters community in undergraduate research From the WashU Newsroom… When Washington University in St. Louis student Sneha Chaturvedi walks into a laboratory, she knows what to expect: sterile white floors, test tubes lining the shelves, a chemical smell wafting between benches and men in lab coats. Few of the scientists are women or underrepresented […]

Botero receives NSF EAGER grant

From WashU Research Wire… Carlos Botero, assistant professor of biology in Arts & Sciences, was awarded a one-year $149,729 National Science Foundation EAGER grant for the project “Removing barriers to macro-ecoevolutionary studies of the avian brain.” The new award will allow Botero to build out a dataset that integrates studies on brain size variation with […]

WashU weekly Neuroscience publications

“Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo” (2018) Nature Communications Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo (2018) Nature Communications, 9 (1), art. no. 2734, .  Li, L.a , Shemetov, A.A.b , Baloban, M.b , Hu, P.c , Zhu, L.c d , Shcherbakova, D.M.b , […]

WashU weekly Neuroscience publications

"Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum" (2018) Nature Communications Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum (2018) Nature Communications, 9 (1), art. no. 2710, .  Wolfman, S.L.a , Gill, D.F.a , Bogdanic, F.b , Long, K.c , Al-Hasani, R.d , McCall, J.G.d e f , Bruchas, M.R.e f , McGehee, […]

Unless we spot changes, most life experiences are fabricated from memories

Change detection plays key role in how we construct reality, new model suggests From the WashU Newsroom… We may not be able to change recent events in our lives, but how well we remember them plays a key role in how our brains model what’s happening in the present and predict what is likely to […]

WashU weekly Neuroscience publications

Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) Scientific Reports Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) Scientific Reports, 8 (1), art. no. 10168, .  Ni, G.a b , Gratten, J.c d , Wray, N.R.c d , Lee, S.H.a b d , Ripke, S.e f , […]

Perfectionism in young children may indicate OCD risk

Study involving behavior, brain scans may help ID issues early in life From the WashU School of Medicine News… Studying young children, researchers at Washington University School of Medicine in St. Louis found that kids who possess tendencies toward perfectionism and excessive self-control are twice as likely as other children to develop obsessive-compulsive disorder (OCD) […]

WashU weekly Neuroscience publications

The Open Source GAITOR Suite for Rodent Gait Analysis (2018) Scientific Reports, 8 (1), art. no. 9797, .  Jacobs, B.Y.a , Lakes, E.H.a , Reiter, A.J.b , Lake, S.P.b , Ham, T.R.c , Leipzig, N.D.c , Porvasnik, S.L.a , Schmidt, C.E.a , Wachs, R.A.a d , Allen, K.D.a a University of Florida, J. Crayton Pruitt Family Department of Biomedical Engineering, Gainesville, United […]

VIP neurons hold master key to jet lag response

A tiny population of neurons can unlock the body’s clock From the WashU Newsroom… Travel by airplane has opened the door to experiencing different cultures and exploring natural wonders. That is, if you can get past the jet lag. But what if you could take control of the brain’s daily timing system? Biologists at Washington […]

WashU weekly Neuroscience publications

Development of vestibular behaviors in zebrafish (2018) Current Opinion in Neurobiology, 53, pp. 83-89.  Bagnall, M.W.a , Schoppik, D.b a Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States b Departments of Otolaryngology, Neuroscience & Physiology, the Neuroscience Institute, New York University School of Medicine, New York, NY, United States Abstract Most animals orient their bodies with […]

WashU weekly Neuroscience publications

Testing neurophysiological markers related to fear-potentiated startle (2018) Psychiatry Research, 267, pp. 195-200.  Seligowski, A.V.a b , Bondy, E.c , Singleton, P.a b , Orcutt, H.K.d , Ressler, K.J.a b , Auerbach, R.P.b e f a Department of Psychiatry, Harvard Medical School, Boston, MA, United States b McLean Hospital, Belmont, MA, United States c Department of Psychological and Brain Sciences, Washington University […]

Barch receives $3.5 million for research on brain, mental illness

From the WashU Newsroom… Mental health researcher Deanna Barch, of Washington University in St. Louis, has been awarded a $3.5 million MERIT award from the National Institute of Mental Health, part of the National Institutes of Health (NIH). Barch Barch is chair of the Department of Psychological & Brain Sciences in Arts & Sciences and the Gregory […]

WashU weekly Neuroscience publications

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states (2018) Scientific Reports, 8 (1), art. no. 4103, .  Mahjoub, I.a b , Mahjoub, M.A.b , Rekik, I.a , Weiner, M.c , Aisen, P.d , Petersen, R.e , Jack, C.f , Jagust, W.g , Trojanowki, J.h , Toga, A.i , Beckett, L.j , Green, R.k , Saykin, A.l , Morris, […]

WashU weekly Neuroscience publications

Brain APOE expression quantitative trait loci-based association study identified one susceptibility locus for Alzheimer’s disease by interacting with APOE ϵ4 (2018) Scientific Reports, 8 (1), art. no. 8068, .  Zhang, A.a , Zhao, Q.b , Xu, D.a , Jiang, S.c a Department of Gynecology, Third Xiangya Hospital of Central South University, Changsha, Hunan, China b Department of Pediatrics, University of Texas MD Anderson […]

WashU weekly Neuroscience publications

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation (2018) Nature Communications, 9 (1), art. no. 2036, .  Voet, S.a b , Mc Guire, C.a b c d , Hagemeyer, N.e , Martens, A.a b , Schroeder, A.f g , Wieghofer, P.e n , Daems, C.h , Staszewski, O.e , …Prinz, M.e m , Van Loo, G.a b a VIB Center for […]

WashU weekly Neuroscience publications

ModCHIMERA: A novel murine closed-head model of moderate traumatic brain injury (2018) Scientific Reports, 8 (1), art. no. 7677, .  Sauerbeck, A.D.a , Fanizzi, C.a b , Kim, J.H.a , Gangolli, M.c , Bayly, P.V.d , Wellington, C.L.e , Brody, D.L.a , Kummer, T.T.a a Department of Neurology, Washington University School of Medicine in St. Louis, St. Louis, MO, United States b Department […]

Act fast to pay attention

Arts & Sciences research sheds new light on attention From the WashU Newsroom… Do you waste time in the morning looking for your keys? Try writing the word “KEYS” on a light switch you use every morning, and you might find them a little quicker. That’s a suggestion based on brain-sciences memory research at Washington University […]

WashU weekly Neuroscience publications

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 (2018) Scientific Reports, 8 (1), art. no. 7352, .  Ostrom, Q.T.a b c , Kinnersley, B.d , Wrensch, M.R.e , Eckel-Passow, J.E.f , Armstrong, G.a , Rice, T.e , Chen, Y.b , Wiencke, J.K.e , McCoy, L.S.e , Hansen, H.M.e , […]

Splitting the difference: One person, two minds

Schecter’s book on ‘split’ consciousness out June 1 From the WashU Newsroom… Each of them, despite being two thinking things, is one of us — one person. It is an odd sentence to most, but not to Lizzie Schechter, assistant professor of philosophy and philosophy-neuroscience-psychology, both in Arts & Sciences, at Washington University in St. Louis. Schechter […]

WashU weekly Neuroscience publications

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21(2018) Scientific Reports, 8 (1), art. no. 7352.  Ostrom, Q.T.a b c , Kinnersley, B.d , Wrensch, M.R.e , Eckel-Passow, J.E.f , Armstrong, G.a , Rice, T.e , Chen, Y.b , Wiencke, J.K.e , McCoy, L.S.e , Hansen, H.M.e , Amos, C.I.g , Bernstein, J.L.h , Claus, E.B.i j , Il’yasova, D.k l m , Johansen, C.n o , Lachance, D.H.p , Lai, […]

WashU weekly Neuroscience publications

Common genetic contributions to high-risk trauma exposure and self-injurious thoughts and behaviors (2018) Psychological Medicine, pp. 1-10. Article in Press.  Richmond-Rakerd, L.S.a b , Trull, T.J.b , Gizer, I.R.b , McLaughlin, K.b , Scheiderer, E.M.b c , Nelson, E.C.d , Agrawal, A.d , Lynskey, M.T.e , Madden, P.A.F.d , Heath, A.C.d , Statham, D.J.f , Martin, N.G.g  a Department of Psychology & Neuroscience, Duke University, Durham, NC, USA b Department of Psychological Sciences, University […]

Five PhD students inducted as Bouchet fellows

From the WashU Newsroom… Five PhD candidates at Washington University in St. Louis were inducted into the Edward A. Bouchet Graduate Honor Society at the annual Bouchet Conference on Diversity and Graduate Education April 26-28 at Yale University. Washington University’s 2018 Bouchet fellows are: Andrae Banks in social work; Robert O. Motley Jr. in social work; Elisa Murray […]

WashU weekly Neuroscience publications

Focused Ultrasound-enabled Brain Tumor Liquid Biopsy (2018) Scientific Reports, 8 (1), art. no. 6553, .  Zhu, L.a , Cheng, G.a , Ye, D.b , Nazeri, A.c , Yue, Y.b , Liu, W.d , Wang, X.d , Dunn, G.P.e f , Petti, A.A.g h , Leuthardt, E.C.a b e i j , Chen, H.a d  a Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO, United States b Department of Mechanical Engineering and Materials Science, Washington University in […]

Undergrads Chen and Wang share Quatrano Prize

From the WashU Newsroom… Alex Chen and Yixi Wang, seniors majoring in biology in Arts & Sciences, have been awarded the 2018 Ralph S. Quatrano Prize. Established through a generous donation by Katherine Day Reinleitner, the Quatrano Prize is awarded to the thesis showing greatest evidence of creativity in design, research methodology and/or broader scientific […]

WashU weekly Neuroscience publications

Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging (2018) Korean Journal of Radiology, 19 (3), pp. 498-507.  Wang, Y.a c , Zhang, R.a , Tao, C.b , Xu, Z.a , Chen, W.a , Wang, C.a , Song, L.a , Zheng, J.d , Gao, F.a  a Department of Radiology, West China Hospital, Sichuan University, Chengdu, China […]

WashU weekly Neuroscience publications

CXCR4 involvement in neurodegenerative diseases (2018) Translational Psychiatry, 8 (1), art. no. 73.  Bonham, L.W.a , Karch, C.M.b , Fan, C.C.c , Tan, C.d , Geier, E.G.a , Wang, Y.e , Wen, N.b , Broce, I.J.d , Li, Y.d , Barkovich, M.J.d , Ferrari, R.f , Hardy, J.f , Momeni, P.g , Höglinger, G.h i , Müller, U.j , Hess, C.P.d , Sugrue, L.P.d , Dillon, W.P.d , Schellenberg, G.D.k , Miller, B.L.a , Andreassen, O.A.e , Dale, A.M.c l , Barkovich, A.J.d , Yokoyama, […]

Bowen, Perlmutter elected to American Academy of Arts and Sciences

From the WashU Newsroom… Washington University in St. Louis sociocultural anthropologist John R. Bowen and David H. Perlmutter, MD, dean of the School of Medicine, join the likes of President Barack Obama, actor Tom Hanks and Supreme Court Justice Sonia M. Sotomayor as newly elected members of the American Academy of Arts and Sciences, the academy announced April 18. […]

Achilefu, Elgin to receive 2018 faculty achievement awards

Frazier to be honored for innovation and entrepreneurship From the WashU Newsroom… Samuel I. Achilefu and Sarah C.R. Elgin will receive Washington University in St. Louis’ 2018 faculty achievement awards, Chancellor Mark S. Wrighton announced. Achilefu, the Michel M. Ter-Pogossian Professor of Radiology at the School of Medicine, will receive the Carl and Gerty Cori Faculty Achievement Award. Elgin, […]

WashU weekly Neuroscience publications

Distinct phase-amplitude couplings distinguish cognitive processes in human attention (2018) NeuroImage, 175, pp. 111-121.  Chacko, R.V., Kim, B., Jung, S.W., Daitch, A.L., Roland, J.L., Metcalf, N.V., Corbetta, M., Shulman, G.L., Leuthardt, E.C. Abstract Spatial attention is the cognitive function that coordinates the selection of visual stimuli with appropriate behavioral responses. Recent studies have reported that phase-amplitude coupling (PAC) of […]

Board of Trustees grants faculty appointments, promotions

From the WashU Newsroom… At the Washington University in St. Louis Board of Trustees meeting March 2, the following faculty members were appointed with tenure, promoted with tenure or granted tenure, effective July 1 unless otherwise noted. Appointment with tenure Cynthia Feliciano as professor of sociology in Arts & Sciences (effective at the beginning of employment); […]

WashU weekly Neuroscience publications

The choroid plexus is an important circadian clock component (2018) Nature Communications, 9 (1), art. no. 1062.  Myung, J.a b c d e , Schmal, C.f , Hong, S.b , Tsukizawa, Y.g , Rose, P.f , Zhang, Y.h , Holtzman, M.J.h, De Schutter, E.b , Herzel, H.f , Bordyugov, G.f , Takumi, T.a g  a RIKEN Brain Science Institute (BSI), Wako, Japan b Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa, Japan c Graduate Institute […]

WashU Spaces: Keith Hengen

Using cutting-edge technology, big data and caffeine to discover how neurons interact From the WashU Newsroom… Have you ever confused a coffee cup for a pen? Or a mango? Or your Aunt Beatrice? Of course not. Sure, maybe you once poured coffee into your cereal. But that’s because you were distracted or sleepy, not because […]

How to Think about “Implicit Bias”

Amidst a controversy, it’s important to remember that implicit bias is real—and it matters From Scientific American… When is the last time a stereotype popped into your mind? If you are like most people, the authors included, it happens all the time. That doesn’t make you a racist, sexist, or whatever-ist. It just means your […]

Bono debut book tackles strategies for happiness

‘When Likes Aren’t Enough: A Crash Course in the Science of Happiness’ released From the WashU Newsroom… How can we be happier? In a world where stress, anxiety and bad days can easily overtake the good, happiness expert Tim Bono, lecturer in psychology in Arts & Sciences at Washington University in St. Louis, strives to […]

Grad students Hoye, Kaufman awarded 2018 O’Leary Prize

Congratulations to the 2018 winners of the James L. O’Leary Prize for Excellence in Neuroscience Research! Mariah Hoye, Graduate student in the Biochemistry Program; lab of Timothy Miller Sarah Kaufman, MD/PhD student in the Neuroscience Program; lab of Marc Diamond Winners were selected based on presentations by graduate student and post doc finalists at the March […]

Seven faculty are 2017 AAAS Fellows

From the WashU Newsroom… Seven faculty members at Washington University in St. Louis are among 396 new fellows selected by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society. Michael G. Caparon Jr.; Graham A. Colditz, MD, DrPH; John A. Cooper, MD, PhD; Michael S. Diamond, MD, PhD; Susan K. Dutcher; Timothy J. Eberlein, MD — all […]

Penny-wise, pound-foolish decisions explained by neurons’ firing

Spending decisions influenced by adaptation in neural circuits From the WashU Newsroom… The British have a pithy way of describing people who dither over spending 20 cents more for premium ice cream but happily drop an extra $5,000 for a fancier house: penny wise and pound foolish. Now, a new study suggests that being penny wise […]

Early childhood adversities linked to health problems in tweens, teens

Study is first to point to brain changes that underlie poor health in some children From the WashU Newsroom… Adverse experiences in childhood — such as the death of a parent, growing up in poverty, physical or sexual abuse, or having a parent with a psychiatric illness — have been associated with physical and mental health […]

Which came first: big brains or demanding environments?

Testing the idea that environmental challenges drive the evolution of bigger brains From the WashU Newsroom… Given how proud we are of our big brains, it’s ironic that we haven’t yet figured out why we have them. One idea, called the cognitive buffer hypothesis, is that the evolution of large brains is driven by the adaptive […]

Conference to focus on early brain development, social outcomes

Universitywide initiative explores intersection of neuroscience and societal issues From the WashU Newsroom… In recent years, research has emerged detailing the detrimental effects of poverty and stress on early brain development. Such societal ills can reshape the human brain and cause lifelong problems in behavior, learning, physical health and mental wellbeing. To explore these connections, Washington […]

Poverty linked to childhood depression, changes in brain connectivity

Conditions associated with poverty appear to interfere with how key brain regions connect and increase depression risk in children From the WashU Newsroom… Many negative consequences are linked to growing up poor, and researchers at Washington University St. Louis have identified one more: altered brain connectivity. Analyzing brain scans of 105 children ages 7 to 12, […]