The risk of developing long COVID has decreased significantly over the course of the COVID-19 pandemic, according to an analysis of data led by Washington University School of Medicine in St. Louis. Researchers attributed about 70% of the risk reduction to vaccination against COVID-19 and 30% to changes over time, including the SARS-CoV-2 virus’s evolving […]
As the deadly disease that came to be known as COVID-19 started spreading in late 2019, scientists rushed to answer a critical question: Who is most at risk? They quickly recognized that a handful of characteristics — including age, smoking history, high body mass index (BMI) and the presence of other diseases such as diabetes […]
New findings on long COVID — long-term effects on health experienced by many who have had COVID-19 — present a good-news, bad-news situation, according to a study at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system. The bad news: COVID-19 patients who were hospitalized within the […]
Chakrabarty, Cirrito to develop test with $3.6 million grant from Flu Lab
In 2020, overwhelmed hospitals and excessive fatalities defined a world grappling with the COVID-19 pandemic. Simultaneously, a new challenge emerged: A growing population struggled to recover fully from COVID-19. Patients coined the term “long COVID” to describe their prolonged health challenges that can linger months after initial coronavirus infection. Eventually, long-COVID clinics, programs focused on […]
Many symptoms of long COVID are related to the brain. Now scientists are beginning to understand why brain fog, fatigue, and pain can linger for years after a person was infected. ARI SHAPIRO, HOST: Months or even years after getting COVID-19, some people still have neurological symptoms like pain, fatigue and brain fog. MICHELLE WILSON: […]
Scientists at Washington University in St. Louis have developed a breath test that quickly identifies those who are infected with the virus that causes COVID-19. The device requires only one or two breaths and provides results in less than a minute. The study is available online in the journal ACS Sensors. The same group of […]
Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses. By combining recent advances in aerosol sampling technology and an ultrasensitive biosensing technique, researchers at Washington University in St. Louis have created a real-time monitor that can detect any of […]
One of the more intriguing paradoxes emerging from the rubble of the COVID-19 pandemic is new evidence suggesting that older adults — those at the greatest risk of severe illness and death from the virus — fared much better than their younger counterparts when it comes to coping with pandemic-related distress, anxiety, depression and social […]
In this episode, we learn more about one of the leading problems associated with long COVID-19. Those who have been infected with the virus are at increased risk for a range of neurological conditions in the first year after an infection. Research conducted at the School of Medicine and the Veterans Affairs St. Louis Health […]
Researchers at Washington University School of Medicine in St. Louis have received a grant from the Centers for Disease Control and Prevention (CDC) totaling $12.5 million to investigate the real-world effectiveness of influenza and COVID-19 vaccines and the immune response to infection and vaccination against these two illnesses. Unlike a strictly controlled clinical trial, this […]
Several studies on COVID-19 have revealed gaping disparities in the U.S. that negatively affect the health of people who aren’t white, especially nonwhite women. A deep dive from researchers at Washington University School of Medicine in St. Louis and the university’s Brown School shows that in St. Louis County, Black women suffered at disproportionately higher […]
Since the COVID-19 pandemic began almost three years ago, scientists have learned that an initial infection can lead to short- and long-term health risks affecting nearly every organ system in the body. They’ve also determined that people can get COVID-19 a second or a third time, despite acquiring natural antibodies after the first infection and […]
During the height of the COVID-19 pandemic, it wasn’t unusual to see and hear public health announcements geared toward older populations because they were more susceptible to severe illness. Over and over, older adults were referred to as “vulnerable.” Meghan McDarby, a former PhD student, Catherine Ju, a former undergraduate student, and Matthew Picchiello, a […]
If you’ve had COVID-19, it may still be messing with your brain. Those who have been infected with the virus are at increased risk of developing a range of neurological conditions in the first year after the infection, new research shows. Such complications include strokes, cognitive and memory problems, depression, anxiety and migraine headaches, according […]
People who were more distressed — showing signs of anxiety or depression — during the COVID-19 pandemic were less likely to follow some best practice recommendations from the Centers for Disease Control and Prevention, according to a new study by Washington University in St. Louis researchers. They found, however, that those same people were more […]
Investigators at Washington University School of Medicine in St. Louis conduct many clinical trials and translational research studies each year to develop and evaluate new ways of treating and diagnosing myriad types of diseases. Such research holds promise for improving the health of people living in St. Louis, across the state of Missouri and around […]
While having a child attend a private school or school with above-average instructional quality was associated with better mental health of parents during the COVID-19 pandemic, hybrid school was associated with worse parental mental health, as was working from home, finds a new study from the Brown School at Washington University in St. Louis. The study is […]
The death toll isn’t the only staggering statistic from the first two years of the pandemic. What’s become increasing clear is that some COVID-19 patients don’t get well right away. Since the earliest days of the pandemic, we’ve heard of survivors who continue to experience shortness of breath, extreme fatigue, lingering difficulty with taste and […]
Adding to a growing body of evidence that, for many, problems related to COVID-19 linger longer than the initial infection, researchers at Washington University School of Medicine in St. Louis have found that some people infected during the pandemic’s early months experienced peripheral neuropathy — pain, tingling and numbness in the hands and feet — […]
Rochelle P. Walensky, MD, the director of the Centers for Disease Control and Prevention (CDC), visited Washington University School of Medicine last week to discuss lessons learned from the COVID-19 pandemic. As part of the Department of Medicine’s weekly Grand Rounds series, she sat down March 3 with William G. Powderly, MD, the J. William […]
The director of the Centers for Disease Control and Prevention, Rochelle P. Walensky, MD, will participate in a conversation about the pandemic Thursday, March 3, from 8 to 9 a.m. at Washington University School of Medicine in St. Louis. The virtual event, available via livestream, will be geared toward faculty, staff, students and trainees on the […]
This episode of ‘Show Me the Science’ focuses on the pandemic’s role in anxiety, depression and other issues for health-care workers, as well as how to train future workers to get help before burnout begins. With U.S. hospitals crowded with COVID-19 patients for almost two years, the pandemic’s relentlessness has pushed many doctors, nurses and […]
As the COVID-19 pandemic stretches into its third year, countless people have experienced varying degrees of uncertainty, isolation and mental health challenges. However, those who have had COVID-19 have a significantly higher chance of experiencing mental health problems, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. […]
After two years of wearing layers of protective equipment on crowded hospital floors and working shift after shift with COVID-19 patients, many front-line health-care workers are suffering burnout, anxiety, depression and other difficulties. Consequently, many have left the field or started to question whether to remain. Reducing burnout and promoting mental health and wellness among […]
When students were told to stay home after COVID-19 began to spread stateside, it’s not surprising that their social media use increased — there wasn’t much else to do. But was it all doom scrolling and catastrophizing or was social media living up to its promise to keep people connected and strengthen our ties to […]
In the largest study yet to evaluate a common, low-cost antidepressant as a treatment for COVID-19, researchers from Washington University School of Medicine in St. Louis and from Canada and Brazil have found that the drug fluvoxamine prevents some of the most serious complications of COVID-19, sharply reducing the risk of hospitalization and death. The […]
Researchers at Washington University School of Medicine in St. Louis have received a five-year, $9.1 million grant from the National Institute on Aging of the National Institutes of Health (NIH) to study resilience in older adults before and during the COVID-19 pandemic. The grant also will fund research into the pandemic’s cognitive and emotional effects […]
Studies have determined that in-school transmission of the virus that causes COVID-19 is rare when masking, social distancing and other safety protocols are followed. However, little has been known about COVID-19 risks at school for children with intellectual and developmental disabilities. These students often are unable to mask or maintain social distancing and may have underlying […]
Should doctors take particular care to talk to patients about the potential dangers of COVID-19 if those patients have a problematic relationship with pot? New research from Washington University in St. Louis suggests perhaps they should. Diabetes, obesity and a history of smoking cigarettes are all considered risk factors for poorer COVID-19 outcomes. Warnings and […]
The coronavirus pandemic has emphasized the importance of vaccines, particularly for the elderly, who have been disproportionately impacted by the virus. However, a decline in immune response as well as inflammation that accompanies aging require a booster to improve the immune response. Jai Rudra, PhD, assistant professor of biomedical engineering at the McKelvey School of […]
Many Americans are facing mental health challenges as they deal with the tumult of the last year and the uncertainties ahead. The pandemic has caused waves of isolation and grief. Police violence and systemic racism have elevated fears and frustrations — triggering important conversations as well as powerful stressors. For many, the return to some […]
ARI SHAPIRO, HOST: Loss of smell has become a hallmark of COVID-19. Up to 80% of infected people experience it. While most people get their sense of smell back as they recover, some do not. And, as Will Stone reports, this phenomenon has triggered new interest and research studies in the field of smell. WILL […]
Throughout the pandemic, doctors have seen evidence that men with COVID-19 fare worse, on average, than women with the infection. One theory is that hormonal differences between men and women may make men more susceptible to severe disease. And since men have much more testosterone than women, some scientists have speculated that high levels of […]
As the COVID-19 pandemic has progressed, it has become clear that many survivors — even those who had mild cases — continue to manage a variety of health problems long after the initial infection should have resolved. In what is believed to be the largest comprehensive study of long COVID-19 to date, researchers at Washington […]
Infections with the virus that causes COVID-19 are not the only cause of pandemic-related hospitalizations. Although children tend to be at lower risk of COVID-19, the number of kids with mental health and behavioral problems has exploded during the pandemic, driving an increase in pediatric hospital admissions nationwide. Stressors associated with remote schooling, fear of […]
As the COVID-19 pandemic surged last summer and contact tracers struggled to identify sources of infections, John Cirrito, PhD, an associate professor of neurology at Washington University School of Medicine in St. Louis, and Carla Yuede, PhD, an associate professor of psychiatry, began to kick around an idea. Could a biosensor they’d developed years ago for Alzheimer’s disease […]
In the year since COVID-19 infections first appeared in the United States, a few things have become clear. One is that many who get sick don’t recover quickly. Even those who don’t have to be hospitalized can experience symptoms that linger. Called long-haulers, these individuals suffer from a variety of issues such as shortness of […]
Elizabeth Tesson remembers the exact moment she lost her sense of smell, the day after she tested positive for COVID-19. “I got a very odd feeling in my nose, like a burning sensation in my sinuses and along my cheeks,” said Tesson, who lives in St. Louis County. “About an hour and a half later, […]
Edelmira Rivera was lying on her bed with her husband and 16-month-old son, selecting a movie when she heard a loud bang outside their home in Waco, Texas. Her sister screamed, “Fire!” “I dropped everything and just grabbed my son and his blanket,” said Rivera, 22. “I could not smell anything. I was so shocked […]
Doctors are running a clinical trial to see if a popular anti-depressant might keep someone from becoming severely ill with Covid-19. The researchers at Washington University of St. Louis are recruiting 1,100 people in the beginning stages of Covid-19 to test out the drug fluvoxamine, also known as Luvox. While an anti-depressant may seem like […]
A new episode of our podcast, “Show Me the Science,” has been posted. At present, these podcast episodes are highlighting research and patient care on the Washington University Medical Campus as our scientists and clinicians confront the COVID-19 pandemic. COVID-19 vaccine development has been rapid and successful. Two vaccines that report more than 90% efficacy […]
In a preliminary study of COVID-19 patients with mild-to-moderate disease who were attempting to recover in their homes, researchers at Washington University School of Medicine in St. Louis have found that the drug fluvoxamine seems to prevent some of the most serious complications of the illness and make hospitalization and the need for supplemental oxygen […]
New findings from researchers at Washington University School of Medicine in St. Louis suggest the eye’s cornea can resist infection from the novel coronavirus. Although the herpes simplex virus can infect the cornea and spread to other parts of the body in patients with compromised immune systems, and Zika virus has been found in tears […]
The pandemic is affecting everyone, but the stresses it causes are particularly rough for those with intellectual and developmental disabilities and their families. Providing effective education to such children and getting services to those who need help in their homes is typically complex, but those issues are even more difficult in the face of COVID-19. […]
Many of the most common diseases — cancer, diabetes, cardiovascular and lung disease, and even COVID-19 — have been linked to chronic or excessive inflammation. Blood tests can indicate that some part of a person’s body is inflamed, but doctors don’t have a good way to zero in on the site of inflammation and visualize the […]
As the nation’s children, teens and college students attempt to start a new school year amidst debate regarding how best to resume education during the COVID-19 pandemic, a segment of the population in desperate need of in-person supports often is overlooked in the decision-making process, according to a group of experts on the topic. “In […]
A new saliva test to detect the SARS-CoV-2 virus has been developed by researchers at Washington University School of Medicine in St. Louis. Results from the COVID-19 diagnostic test are available in a few hours and, ideally, able to be communicated to people tested within a day. Highly sensitive to detecting even tiny levels of […]
It was one thing to navigate the initial stress and disruptions of the coronavirus pandemic. And early on, as people looked for ways to guard mental well-being amid big changes, many realized that it helped to have a sense of horizon in sight. “I can shelter in place for a month” and “One semester at […]
The impact of social media on anxiety and stress during the coronavirus pandemic is the focus of a new study led by mental health experts at Washington University School of Medicine in St. Louis and computer scientists at Georgia Tech. The National Science Foundation is funding the pilot study. The researchers plan to use computer […]