Category: Weekly Publications

“A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine” (2020) Nature Communications A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine (2020) Nature Communications, 11 (1), art. no. 3368, . Guo, Y.a b c , Rist, P.M.a b c , Daghlas, I.a b , Giulianini, F.a , Gormley, P.e f g h , Anttila, V.f g i , Winsvold, B.S.j k l , Palta, P.m , Esko, T.f n o , Pers, T.H.f o p q , Farh, K.-H.f i r , Cuenca-Leon, E.e f g s , Muona, […]

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Praesent euismod, quam at feugiat commodo, turpis orci feugiat justo, nec porta nibh lectus vitae dui. Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific Reports, (2019), 9, 1, (13845), 10.1038/s41598-019-49970-9) (2020) Scientific Reports Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific […]

“Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples” (2020) Translational Psychiatry Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples (2020) Translational Psychiatry, 10 (1), art. no. 196, . Barr, P.B.a , Ksinan, A.b , Su, J.c , Johnson, E.C.d , […]

“Entropy, mutual information, and systematic measures of structured spiking neural networks” (2020) Journal of Theoretical Biology Entropy, mutual information, and systematic measures of structured spiking neural networks (2020) Journal of Theoretical Biology, 501, art. no. 110310, . Li, W.a , Li, Y.b a Department of Mathematics and Statistics, Washington University, St. Louis, MO 63130, United States b Department […]

“GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors” (2020) Scientific Reports GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors (2020) Scientific Reports, 10 (1), art. no. 9027, . Fu, Y.a b , Liu, C.J.a b , Kobayashi, D.K.a b , Johanns, T.M.b c , Bowman-Kirigin, J.A.a , Schaettler, M.O.a , Mao, D.D.a , Bender, D.b , Kelley, D.G.d , Uppaluri, R.e , Bi, W.L.f , Dunn, I.F.g , […]

“Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program” (2020) Nature Communications Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program (2020) Nature Communications, 11 (1), art. no. 2611, .  Karagiannis, T.T.a b , Cleary, J.P., Jr.b c , Gok, B.b d , Henderson, A.J.e , Martin, N.G.f , Yajima, M.g , Nelson, […]

“Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia” (2020) Nature Communications Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia (2020) Nature Communications, 11 (1), art. no. 2552, .  Wang, P.L.a b , Yim, A.K.Y.b , Kim, K.-W.a , Avey, D.b , Czepielewski, R.S.a , Colonna, M.a , Milbrandt, J.b , Randolph, G.J.a a Division […]

“The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity” (2020) Operative Neurosurgery (Hagerstown, Md.) The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity (2020) Operative Neurosurgery (Hagerstown, Md.), 18 (6), pp. 583-589. Segreto, F.A.a b , Passias, P.G.a b , Brown, A.E.a b , Horn, S.R.a b , Bortz, C.A.a b , Pierce, K.E.a b , Alas, H.a b , […]

“Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model” (2020) Scientific Reports Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model (2020) Scientific Reports, 10 (1), art. no. 7449, .  Pacia, C.P.a , Zhu, L.a , Yang, Y.a , Yue, Y.a , Nazeri, A.b , Michael Gach, H.a b […]

“The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry” (2020) International Journal of Bipolar Disorders The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective […]

“Ocular and brain imaging findings in Peters’ anomaly: A case report and literature review” (2020) Radiology Case Reports Ocular and brain imaging findings in Peters’ anomaly: A case report and literature review (2020) Radiology Case Reports, 15 (7), pp. 863-866.  Samara, A.a , Eldaya, R.W.b a Department of Psychiatry, Washington University School of Medicine, 4525 Scott Ave, St. Louis, MO 63110, […]

“The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease” (2020) Current Opinion in Neurobiology The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease (2020) Current Opinion in Neurobiology, 63, pp. 59-66.  Figley, M.D.a , DiAntonio, A.a b a Department of Developmental Biology, Washington University […]

“cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons” (2020) Experimental Neurology cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons (2020) Experimental Neurology, 329, art. no. 113252, .  Sasaki, Y.a , Engber, T.M.b , Hughes, R.O.b , Figley, M.D.c , Wu, T.a , Bosanac, T.b , Devraj, […]

“Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective” (2020) Neurobiology of Stress Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective (2020) Neurobiology of Stress, 12, art. no. 100215, .  Paul, S.M.a b c , Pinna, G.d , Guidotti, A.d e a Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States b The Taylor Family Institute for […]

“Modafinil in Recovery after Stroke (MIRAS): A Retrospective Study” (2020) Journal of Stroke and Cerebrovascular Diseases Modafinil in Recovery after Stroke (MIRAS): A Retrospective Study (2020) Journal of Stroke and Cerebrovascular Diseases, 29 (4), art. no. 104645, .  Cross, D.B.a , Tiu, J.c , Medicherla, C.a , Ishida, K.a , Lord, A.a , Czeisler, B.a , Wu, C.a , Golub, D.a […]

“Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology” (2020) Scientific Reports Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) Scientific Reports, 10 (1), art. no. 2975, .  Shen, X.a , Ma, S.a , Vemuri, P.b , Simon, G.a , Weiner, M.W.c , Aisen, P.d , Petersen, R.b , Jack, C.R.b , Saykin, A.J.e , […]

“Genomic prediction of alcohol-related morbidity and mortality” (2020) Translational Psychiatry Genomic prediction of alcohol-related morbidity and mortality (2020) Translational Psychiatry, 10 (1), art. no. 23, .  Kiiskinen, T.a f , Mars, N.J.f , Palviainen, T.f , Koskela, J.f , Rämö, J.T.f , Ripatti, P.f , Ruotsalainen, S.f , Palotie, A.f g h , Madden, P.A.F.b , Rose, R.J.c , Kaprio, J.d […]

“Spectral hallmark of auditory-tactile interactions in the mouse somatosensory cortex” (2020) Communications Biology Spectral hallmark of auditory-tactile interactions in the mouse somatosensory cortex (2020) Communications Biology, 3 (1), art. no. 64, .  Zhang, M.a c , Kwon, S.E.b d , Ben-Johny, M.a e , O’Connor, D.H.b , Issa, J.B.a f a Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, […]

“Self-reported sleep disturbance in Crohn’s disease is not confirmed by objective sleep measures” (2020) Scientific Reports Self-reported sleep disturbance in Crohn’s disease is not confirmed by objective sleep measures (2020) Scientific Reports, 10 (1), art. no. 1980, .  Iskandar, H.N.a , Linan, E.E.b , Patel, A.c , Moore, R.d , Lasanajak, Y.d , Gyawali, C.P.b , Sayuk, G.S.b e , Ciorba, […]

“Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy” (2020) Nature Communications Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy (2020) Nature Communications, 11 (1), art. no. 595, .  Hengel, H.a b , Bosso-Lefèvre, C.c d , Grady, G.e , Szenker-Ravi, E.c , Li, H.f , Pierce, S.g , Lebigot, É.h , Tan, T.-T.i , Eio, M.Y.i , […]

“FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease” (2020) Nature Communications FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease (2020) Nature Communications, 11 (1), art. no. 411, .  Yan, T.a , Liang, J.b , Gao, J.a , Wang, L.a , Fujioka, H.c , Weiner, M.W.d , Schuff, N.d , Rosen, H.J.d , Miller, B.L.d , […]

“Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning” (2020) Information Fusion Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning (2020) Information Fusion, 58, pp. 153-167.  Castillo-Barnes, D.a , Su, L.b , Ramírez, J.a , Salas-Gonzalez, D.a , Martinez-Murcia, F.J.c , Illan, I.A.a , Segovia, F.a , Ortiz, A.c , Cruchaga, C.d […]

“Structural basis for adhesion G protein-coupled receptor Gpr126 function” (2020) Nature Communications Structural basis for adhesion G protein-coupled receptor Gpr126 function (2020) Nature Communications, 11 (1), art. no. 194, .  Leon, K.a b , Cunningham, R.L.c , Riback, J.A.a d , Feldman, E.a , Li, J.a b , Sosnick, T.R.a e , Zhao, M.a , Monk, K.R.c f , Araç, D.a […]

“Diffusion basis spectrum imaging provides insights into MS pathology” (2020) Neurology(R) Neuroimmunology & Neuroinflammation Diffusion basis spectrum imaging provides insights into MS pathology (2020) Neurology(R) Neuroimmunology & Neuroinflammation, 7 (2), .  Sun, P., George, A., Perantie, D.C., Trinkaus, K., Ye, Z., Naismith, R.T., Song, S.-K., Cross, A.H. From the Radiology (P.S., A.G., Z.Y., S.-K.S.), Washington University in Saint Louis, […]

“Incidence and predictors of post-traumatic stress symptoms in a cohort of patients with intracerebral hemorrhage” (2020) Clinical Neurology and Neurosurgery Incidence and predictors of post-traumatic stress symptoms in a cohort of patients with intracerebral hemorrhage (2020) Clinical Neurology and Neurosurgery, 190, art. no. 105657, .  Garton, A.L.a , Gupta, V.P.b , Pucci, J.U.c , Couch, C.K.d , Connolly, E.S., Jrc […]

“Clinical instrument to retrospectively capture levels of EDSS” (2020) Multiple Sclerosis and Related Disorders Clinical instrument to retrospectively capture levels of EDSS (2020) Multiple Sclerosis and Related Disorders, 39, art. no. 101884, .  Ciotti, J.R.a , Sanders, N.b , Salter, A.c , Berger, J.R.d , Cross, A.H.a , Chahin, S.a a Department of Neurology, Washington University in St. Louis, St. Louis, […]

“Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan” (2020) NeuroImage Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan (2020) NeuroImage, 208, art. no. 116450, .  Pomponio, R.a , Erus, G.a , Habes, M.a b , Doshi, J.a , Srinivasan, D.a , Mamourian, E.a , Bashyam, V.a […]

“Structural correlates of commission errors in prospective memory” (2020) Cortex Structural correlates of commission errors in prospective memory (2020) Cortex, 124, pp. 44-53.  Scullin, M.K.a , Ball, B.H.b c , Bugg, J.M.b a Baylor University, United States b Washington University in St. Louis, United States c University of Texas, Arlington, United States Abstract Prospective memory refers to remembering to perform an intended […]

“The impact of dopamine D2-like agonist/antagonist on (18F)VAT PET measurement of VAChT in the brain of nonhuman primates” (2020) European Journal of Pharmaceutical Sciences The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates (2020) European Journal of Pharmaceutical Sciences, 143, art. no. 105152, .  Liu, H.a , Luo, Z.a , Gu, […]

“Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear” (2020) Hearing Research Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear (2020) Hearing Research, 385, art. no. 107839, .  Wan, L.a , Lovett, M.b , Warchol, M.E.c , Stone, J.S.a a Virginia Merrill Bloedel Hearing […]

“A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease” (2020) Neurobiology of Disease A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease (2020) Neurobiology of Disease, 134, art. no. 104647, .  Aflaki, E.a , Stubblefield, B.K.a , McGlinchey, R.P.b , McMahon, B.a , Ory, D.S.c , Sidransky, E.a a Section of Molecular Neurogenetics, National Human Genome Research […]

“Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems” (2020) Bone Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems (2020) Bone, 130, art. no. 115144, .  Maximova, N.a , Zennaro, F.b , Gregori, M.a , Boz, G.c , Zanon, […]

“Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis” (2019) Journal of Anxiety Disorders Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis (2019) Journal of […]

“Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction” (2020) Early Human Development Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction (2020) Early Human Development, 140, art. no. 104891, .  Whitehead, H.V.a , Vesoulis, Z.A.a , Maheshwari, A.b , Rambhia, A.a , Mathur, A.M.c a Department of Pediatrics, Division of […]

“Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex” (2020) Neurobiology of Disease Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex (2020) Neurobiology of Disease, 134, art. no. 104615, .  Zhang, B.a , Guo, D.a , Han, L.a , […]

“Identifying reproducible individual differences in childhood functional brain networks: An ABCD study” (2019) Developmental Cognitive Neuroscience Identifying reproducible individual differences in childhood functional brain networks: An ABCD study (2019) Developmental Cognitive Neuroscience, 40, art. no. 100706, .  Marek, S.a , Tervo-Clemmens, B.b , Nielsen, A.N.c , Wheelock, M.D.a , Miller, R.L.d , Laumann, T.O.a , Earl, E.f , Foran, W.W.e […]

“Alzheimer Disease: An Update on Pathobiology and Treatment Strategies” (2019) Cell Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019) Cell, 179 (2), pp. 312-339.  Long, J.M., Holtzman, D.M. Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, United States Abstract Long […]

“Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers” (2019) Neurobiology of Aging Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers (2019) Neurobiology of Aging, 83, pp. 54-62.  Chen, Q.a b , Boeve, B.F.c , Schwarz, C.G.b , Reid, R.b , Tosakulwong, N.d , Lesnick, T.G.d , Bove, J.e , Brannelly, P.f , Brushaber, […]

“The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability” (2019) NeuroImage The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability (2019) NeuroImage, 202, art. no. 115990, .  Betzel, R.F.a b c , Bertolero, M.A.a , Gordon, E.M.d e , Gratton, C.f g , Dosenbach, N.U.F.f h i , […]

“Pioglitazone improves working memory performance when administered in chronic TBI” (2019) Neurobiology of Disease Pioglitazone improves working memory performance when administered in chronic TBI (2019) Neurobiology of Disease, 132, art. no. 104611, .  McGuire, J.L.a , Correll, E.A.a , Lowery, A.C.b , Rhame, K.c , Anwar, F.N.d , McCullumsmith, R.E.e , Ngwenya, L.B.a f a Department of Neurosurgery, University of Cincinnati, […]

“Large posttraumatic stress disorder improvement and antidepressant medication adherence” (2020) Journal of Affective Disorders Large posttraumatic stress disorder improvement and antidepressant medication adherence (2020) Journal of Affective Disorders, 260, pp. 119-123.  Salas, J.a b , Scherrer, J.F.a b , Tuerk, P.c , van den Berk-Clark, C.a , Chard, K.M.d , Schneider, F.D.e , Schnurr, P.P.f , Friedman, M.J.f , […]

“Alternative ecological strategies lead to avian brain size bimodality in variable habitats” (2019) Nature Communications Alternative ecological strategies lead to avian brain size bimodality in variable habitats (2019) Nature Communications, 10 (1), art. no. 3818, .  Fristoe, T.S.a b , Botero, C.A.b a Department of Biology, University of Konstanz, Universitätsstraße 10, Konstanz, 78464, Germany b Department of Biology, Washington University in St. Louis, […]

“Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter” (2019) Scientific Reports Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter (2019) Scientific Reports, 9 (1), art. no. 12246, .  Fukutomi, H.a b , Glasser, M.F.c d , Murata, K.e , […]

"Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex" (2019) Scientific Reports Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex(2019) Scientific Reports, 9 (1), art. no. 11700, .  Maranesi, M.a , Bruni, S.a b , Livi, A.a c , Donnarumma, F.d , Pezzulo, G.d , Bonini, L.a a Department of Medicine […]

“Sleep disturbances in Wolfram syndrome” (2019) Orphanet Journal of Rare Diseases Sleep disturbances in Wolfram syndrome (2019) Orphanet Journal of Rare Diseases, 14 (1), art. no. 188, .  Licis, A.a , Davis, G.d e , Eisenstein, S.A.b c , Lugar, H.M.b , Hershey, T.a b c a Department of Neurology, Washington University, School of Medicine, Campus Box 8111, 660 South Euclid Ave, […]

“Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia” (2019) Scientific Reports Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia (2019) Scientific Reports, 9 (1), art. no. 10854, .  Bonham, L.W.a b , Steele, N.Z.R.a , Karch, C.M.c […]

“A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings” (2019) Journal of Substance Abuse Treatment A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings (2019) Journal of Substance Abuse Treatment, 104, pp. 135-143.  Presnall, N.J.a b , Wolf, D.A.P.S.a , Brown, D.S.a , Beeler-Stinn, S.a , Grucza, R.A.b a Brown School of […]

“CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease)” (2019) Scientific Reports CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease) (2019) Scientific Reports, 9 (1), art. no. 9891, .  Eaton, S.L.a , Proudfoot, C.a , Lillico, S.G.a , Skehel, P.b c , Kline, R.A.a , Hamer, K.e , Rzechorzek, N.M.d […]

“A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation” (2019) Molecular Genetics and Metabolism Reports A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation (2019) Molecular Genetics and Metabolism Reports, 20, art. no. 100484, .  Ahmed, A.a , Ou, L.b , Rudser, K.c , […]

“Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns” (2019) Nature Communications Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns (2019) Nature Communications, 10 (1), art. no. 2548, .  Czamara, D.a , Eraslan, G.b c , Page, C.M.d e , Lahti, J.f g , Lahti-Pulkkinen, M.f h , Hämäläinen, E.i […]