Category: Weekly Publications

“Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study” (2021) Neurobiology of Aging Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study (2021) Neurobiology of Aging, 97, pp. 65-72. Walker, K.A.a , Chawla, S.b , Nogueras-Ortiz, C.b , Coresh, J.c , Sharrett, A.R.c , Wong, D.F.d , Jack, C.R., Jr.e , Spychalla, […]

"Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage" (2021) Brain Research Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage(2021) Brain Research, 1750, art. no. 147169, .  Athiraman, U.a , Liu, M.a , Jayaraman, K.b , Yuan, J.a , […]

“N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury” (2021) Experimental Neurology N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury (2021) Experimental Neurology, 335, art. no. 113507, . Celorrio, M., Rhodes, J., Vadivelu, S., Davies, M., Friess, S.H. Division of Critical Care Medicine, Department of Pediatrics, Washington University in St. Louis School of Medicine, One […]

“Relationships between accelerometry and general compensatory movements of the upper limb after stroke” (2020) Journal of NeuroEngineering and Rehabilitation Relationships between accelerometry and general compensatory movements of the upper limb after stroke (2020) Journal of NeuroEngineering and Rehabilitation, 17 (1), art. no. 138, . Barth, J.a , Klaesner, J.W.a d , Lang, C.E.a b c a Washington University School of Medicine, Program in Physical Therapy, St. Louis, […]

“Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells” (2020) Brain Research Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells (2020) Brain Research, 1749, art. no. 147139, . Matsuhisa, K.a b , Cai, L.a , Saito, A.a b , Sakaue, F.b , Kamikawa, Y.b , Fujiwara, S.b , Asada, R.c , Kudo, Y.d , Imaizumi, K.a a Department of Biochemistry, […]

“Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders” (2021) Journal of Affective Disorders Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders (2021) Journal of Affective Disorders, 278, pp. 563-569. Scherrer, J.F.a , Salas, J.a , Grucza, R.a , Sullivan, M.D.b , Lustman, P.J.c d , […]

“Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis” (2020) Journal of Ophthalmic Inflammation and Infection Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis (2020) Journal of Ophthalmic Inflammation and Infection, 10 (1), art. no. 24, . Sonne, S.J.a , Smith, B.T.b c a St. Louis University School of Medicine, St. […]

“Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents” (2020) Journal of Controlled Release Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents (2020) Journal of Controlled Release, 328, pp. 276-285. Ye, D.a , Luan, J.a , Pang, H.b , Yang, Y.b , Nazeri, A.c , Rubin, J.B.d e , Chen, H.b f a Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, […]

“Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites” (2020) Molecular Pharmacology Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites (2020) Molecular Pharmacology, 98 (4), pp. 280-291.  Germann, A.L., Reichert, D.E., Burbridge, A.B., Pierce, S.R., […]

“Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction” (2020) Nature Communications Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction (2020) Nature Communications, 11 (1), art. no. 4358, . Ozawa, M.a b , Davis, P.a b c e , Ni, J.a , Maguire, J.a , Papouin, T.a d , Reijmers, L.a a Department of Neuroscience, School of Medicine, Tufts University, Boston, MA, United States b Graduate Program in […]

“Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder” (2020) Translational Psychiatry Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder (2020) Translational Psychiatry, 10 (1), art. no. 298, . Lopes, F.L.a , Zhu, K.a , Purves, K.L.b , Song, C.a , Ahn, K.a , Hou, L.a , Akula, N.a , Kassem, L.a , Bergen, S.E.c , Landen, M.c d , Veras, A.B.e , Nardi, […]

“Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice” (2020) Scientific Reports Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice (2020) Scientific Reports, 10 (1), art. no. 13630, . Akkaya, M.a , Bansal, A.b e , Sheehan, P.W.a f , Pena, […]

“Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity” (2020) Nature Communications Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity (2020) Nature Communications, 11 (1), art. no. 3996, . Bariselli, S.a d , Miyazaki, N.L.a , Creed, M.C.b c , Kravitz, A.V.a c a National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States b Washington University Pain Center, St Louis, MO 63110, United States c Departments of Psychiatry, […]

“Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease” (2020) The Journal of Experimental Medicine Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease (2020) The Journal of Experimental Medicine, 217 (11), . Barthélemy, N.R.a , Horie, K.a , Sato, C.a , Bateman, R.J.a b c a Department of Neurology, Washington University School of Medicine, St. Louis, MO b Hope Center for Neurological Disorders, […]

"Gait asymmetry, and bilateral coordination of gait during a six-minute walk test in persons with multiple sclerosis" (2020) Scientific Reports Gait asymmetry, and bilateral coordination of gait during a six-minute walk test in persons with multiple sclerosis(2020) Scientific Reports, 10 (1), art. no. 12382, .  Plotnik, M.a b c , Wagner, J.M.d , Adusumilli, G.e , Gottlieb, A.a , Naismith, R.T.e a Center of Advanced Technologies in Rehabilitation, […]

“A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation” (2020) Communications Biology A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation (2020) Communications Biology, 3 (1), art. no. 385, . Liu, Y.a , Xu, X.b , Gao, J.c , Naffaa, M.M.a , Liang, H.a , Shi, J.a , Wang, H.Z.c , Yang, N.-D.a , Hou, P.a , Zhao, W.a , White, K.M.F.a , Kong, W.a , Dou, A.a , Cui, A.a , Zhang, […]

“Quantification of brain oxygen extraction and metabolism with (15O)-gas PET: A technical review in the era of PET-MRI” (2020) NeuroImage Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI (2020) NeuroImage, 220, art. no. 117136, .  Fan, A.P.a b , An, H.c , Moradi, F.a , Rosenberg, J.a , Ishii, Y.a […]

“A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine” (2020) Nature Communications A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine (2020) Nature Communications, 11 (1), art. no. 3368, . Guo, Y.a b c , Rist, P.M.a b c , Daghlas, I.a b , Giulianini, F.a , Gormley, P.e f g h , Anttila, V.f g i , Winsvold, B.S.j k l , Palta, P.m , Esko, T.f n o , Pers, T.H.f o p q , Farh, K.-H.f i r , Cuenca-Leon, E.e f g s , Muona, […]

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Praesent euismod, quam at feugiat commodo, turpis orci feugiat justo, nec porta nibh lectus vitae dui. Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific Reports, (2019), 9, 1, (13845), 10.1038/s41598-019-49970-9) (2020) Scientific Reports Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific […]

“Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples” (2020) Translational Psychiatry Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples (2020) Translational Psychiatry, 10 (1), art. no. 196, . Barr, P.B.a , Ksinan, A.b , Su, J.c , Johnson, E.C.d , […]

“Entropy, mutual information, and systematic measures of structured spiking neural networks” (2020) Journal of Theoretical Biology Entropy, mutual information, and systematic measures of structured spiking neural networks (2020) Journal of Theoretical Biology, 501, art. no. 110310, . Li, W.a , Li, Y.b a Department of Mathematics and Statistics, Washington University, St. Louis, MO 63130, United States b Department […]

“GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors” (2020) Scientific Reports GATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors (2020) Scientific Reports, 10 (1), art. no. 9027, . Fu, Y.a b , Liu, C.J.a b , Kobayashi, D.K.a b , Johanns, T.M.b c , Bowman-Kirigin, J.A.a , Schaettler, M.O.a , Mao, D.D.a , Bender, D.b , Kelley, D.G.d , Uppaluri, R.e , Bi, W.L.f , Dunn, I.F.g , […]

“Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program” (2020) Nature Communications Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program (2020) Nature Communications, 11 (1), art. no. 2611, .  Karagiannis, T.T.a b , Cleary, J.P., Jr.b c , Gok, B.b d , Henderson, A.J.e , Martin, N.G.f , Yajima, M.g , Nelson, […]

“Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia” (2020) Nature Communications Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia (2020) Nature Communications, 11 (1), art. no. 2552, .  Wang, P.L.a b , Yim, A.K.Y.b , Kim, K.-W.a , Avey, D.b , Czepielewski, R.S.a , Colonna, M.a , Milbrandt, J.b , Randolph, G.J.a a Division […]

“The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity” (2020) Operative Neurosurgery (Hagerstown, Md.) The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity (2020) Operative Neurosurgery (Hagerstown, Md.), 18 (6), pp. 583-589. Segreto, F.A.a b , Passias, P.G.a b , Brown, A.E.a b , Horn, S.R.a b , Bortz, C.A.a b , Pierce, K.E.a b , Alas, H.a b , […]

“Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model” (2020) Scientific Reports Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model (2020) Scientific Reports, 10 (1), art. no. 7449, .  Pacia, C.P.a , Zhu, L.a , Yang, Y.a , Yue, Y.a , Nazeri, A.b , Michael Gach, H.a b […]

“The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry” (2020) International Journal of Bipolar Disorders The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective […]

“Ocular and brain imaging findings in Peters’ anomaly: A case report and literature review” (2020) Radiology Case Reports Ocular and brain imaging findings in Peters’ anomaly: A case report and literature review (2020) Radiology Case Reports, 15 (7), pp. 863-866.  Samara, A.a , Eldaya, R.W.b a Department of Psychiatry, Washington University School of Medicine, 4525 Scott Ave, St. Louis, MO 63110, […]

“The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease” (2020) Current Opinion in Neurobiology The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease (2020) Current Opinion in Neurobiology, 63, pp. 59-66.  Figley, M.D.a , DiAntonio, A.a b a Department of Developmental Biology, Washington University […]

“cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons” (2020) Experimental Neurology cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons (2020) Experimental Neurology, 329, art. no. 113252, .  Sasaki, Y.a , Engber, T.M.b , Hughes, R.O.b , Figley, M.D.c , Wu, T.a , Bosanac, T.b , Devraj, […]

“Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective” (2020) Neurobiology of Stress Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective (2020) Neurobiology of Stress, 12, art. no. 100215, .  Paul, S.M.a b c , Pinna, G.d , Guidotti, A.d e a Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States b The Taylor Family Institute for […]

“Modafinil in Recovery after Stroke (MIRAS): A Retrospective Study” (2020) Journal of Stroke and Cerebrovascular Diseases Modafinil in Recovery after Stroke (MIRAS): A Retrospective Study (2020) Journal of Stroke and Cerebrovascular Diseases, 29 (4), art. no. 104645, .  Cross, D.B.a , Tiu, J.c , Medicherla, C.a , Ishida, K.a , Lord, A.a , Czeisler, B.a , Wu, C.a , Golub, D.a […]

“Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology” (2020) Scientific Reports Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) Scientific Reports, 10 (1), art. no. 2975, .  Shen, X.a , Ma, S.a , Vemuri, P.b , Simon, G.a , Weiner, M.W.c , Aisen, P.d , Petersen, R.b , Jack, C.R.b , Saykin, A.J.e , […]

“Genomic prediction of alcohol-related morbidity and mortality” (2020) Translational Psychiatry Genomic prediction of alcohol-related morbidity and mortality (2020) Translational Psychiatry, 10 (1), art. no. 23, .  Kiiskinen, T.a f , Mars, N.J.f , Palviainen, T.f , Koskela, J.f , Rämö, J.T.f , Ripatti, P.f , Ruotsalainen, S.f , Palotie, A.f g h , Madden, P.A.F.b , Rose, R.J.c , Kaprio, J.d […]

“Spectral hallmark of auditory-tactile interactions in the mouse somatosensory cortex” (2020) Communications Biology Spectral hallmark of auditory-tactile interactions in the mouse somatosensory cortex (2020) Communications Biology, 3 (1), art. no. 64, .  Zhang, M.a c , Kwon, S.E.b d , Ben-Johny, M.a e , O’Connor, D.H.b , Issa, J.B.a f a Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, […]

“Self-reported sleep disturbance in Crohn’s disease is not confirmed by objective sleep measures” (2020) Scientific Reports Self-reported sleep disturbance in Crohn’s disease is not confirmed by objective sleep measures (2020) Scientific Reports, 10 (1), art. no. 1980, .  Iskandar, H.N.a , Linan, E.E.b , Patel, A.c , Moore, R.d , Lasanajak, Y.d , Gyawali, C.P.b , Sayuk, G.S.b e , Ciorba, […]

“Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy” (2020) Nature Communications Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy (2020) Nature Communications, 11 (1), art. no. 595, .  Hengel, H.a b , Bosso-Lefèvre, C.c d , Grady, G.e , Szenker-Ravi, E.c , Li, H.f , Pierce, S.g , Lebigot, É.h , Tan, T.-T.i , Eio, M.Y.i , […]

“FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease” (2020) Nature Communications FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease (2020) Nature Communications, 11 (1), art. no. 411, .  Yan, T.a , Liang, J.b , Gao, J.a , Wang, L.a , Fujioka, H.c , Weiner, M.W.d , Schuff, N.d , Rosen, H.J.d , Miller, B.L.d , […]

“Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning” (2020) Information Fusion Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning (2020) Information Fusion, 58, pp. 153-167.  Castillo-Barnes, D.a , Su, L.b , Ramírez, J.a , Salas-Gonzalez, D.a , Martinez-Murcia, F.J.c , Illan, I.A.a , Segovia, F.a , Ortiz, A.c , Cruchaga, C.d […]

“Structural basis for adhesion G protein-coupled receptor Gpr126 function” (2020) Nature Communications Structural basis for adhesion G protein-coupled receptor Gpr126 function (2020) Nature Communications, 11 (1), art. no. 194, .  Leon, K.a b , Cunningham, R.L.c , Riback, J.A.a d , Feldman, E.a , Li, J.a b , Sosnick, T.R.a e , Zhao, M.a , Monk, K.R.c f , Araç, D.a […]

“Diffusion basis spectrum imaging provides insights into MS pathology” (2020) Neurology(R) Neuroimmunology & Neuroinflammation Diffusion basis spectrum imaging provides insights into MS pathology (2020) Neurology(R) Neuroimmunology & Neuroinflammation, 7 (2), .  Sun, P., George, A., Perantie, D.C., Trinkaus, K., Ye, Z., Naismith, R.T., Song, S.-K., Cross, A.H. From the Radiology (P.S., A.G., Z.Y., S.-K.S.), Washington University in Saint Louis, […]

“Incidence and predictors of post-traumatic stress symptoms in a cohort of patients with intracerebral hemorrhage” (2020) Clinical Neurology and Neurosurgery Incidence and predictors of post-traumatic stress symptoms in a cohort of patients with intracerebral hemorrhage (2020) Clinical Neurology and Neurosurgery, 190, art. no. 105657, .  Garton, A.L.a , Gupta, V.P.b , Pucci, J.U.c , Couch, C.K.d , Connolly, E.S., Jrc […]

“Clinical instrument to retrospectively capture levels of EDSS” (2020) Multiple Sclerosis and Related Disorders Clinical instrument to retrospectively capture levels of EDSS (2020) Multiple Sclerosis and Related Disorders, 39, art. no. 101884, .  Ciotti, J.R.a , Sanders, N.b , Salter, A.c , Berger, J.R.d , Cross, A.H.a , Chahin, S.a a Department of Neurology, Washington University in St. Louis, St. Louis, […]

“Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan” (2020) NeuroImage Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan (2020) NeuroImage, 208, art. no. 116450, .  Pomponio, R.a , Erus, G.a , Habes, M.a b , Doshi, J.a , Srinivasan, D.a , Mamourian, E.a , Bashyam, V.a […]

“Structural correlates of commission errors in prospective memory” (2020) Cortex Structural correlates of commission errors in prospective memory (2020) Cortex, 124, pp. 44-53.  Scullin, M.K.a , Ball, B.H.b c , Bugg, J.M.b a Baylor University, United States b Washington University in St. Louis, United States c University of Texas, Arlington, United States Abstract Prospective memory refers to remembering to perform an intended […]

“The impact of dopamine D2-like agonist/antagonist on (18F)VAT PET measurement of VAChT in the brain of nonhuman primates” (2020) European Journal of Pharmaceutical Sciences The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates (2020) European Journal of Pharmaceutical Sciences, 143, art. no. 105152, .  Liu, H.a , Luo, Z.a , Gu, […]

“Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear” (2020) Hearing Research Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear (2020) Hearing Research, 385, art. no. 107839, .  Wan, L.a , Lovett, M.b , Warchol, M.E.c , Stone, J.S.a a Virginia Merrill Bloedel Hearing […]

“A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease” (2020) Neurobiology of Disease A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease (2020) Neurobiology of Disease, 134, art. no. 104647, .  Aflaki, E.a , Stubblefield, B.K.a , McGlinchey, R.P.b , McMahon, B.a , Ory, D.S.c , Sidransky, E.a a Section of Molecular Neurogenetics, National Human Genome Research […]

“Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems” (2020) Bone Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems (2020) Bone, 130, art. no. 115144, .  Maximova, N.a , Zennaro, F.b , Gregori, M.a , Boz, G.c , Zanon, […]

“Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis” (2019) Journal of Anxiety Disorders Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis (2019) Journal of […]