“AdaptiSPECT-C: A Multi-Module Multi-Pinhole Adaptable SPECT System Dedicated to Brain Imaging”

Hosted by the Department of Biomedical Engineering

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Abstract: AdaptiSPECT-C is a stationary SPECT system, dedicated to clinical and research brain imaging being designed and constructed jointly by teams at the University of Arizona and the University of Massachusetts. It employs adaptable-pinhole collimation of its multiple-detector modules used in imaging. This talk will first introduce the need for and applications of a brain dedicated SPECT system, and then present a short review of past SPECT systems. It will then review construction constraints which lead to the current design, utility of adaptive imaging for correction of multiplexing, improving sampling, varying spatial resolution / sensitivity tradeoffs for different tasks related to activity quantification and lesion detection. This will be followed by discussion of predicted system performance based on simulation studies of clinical imaging, and the status of construction of the system. The talk will end with discussion of estimation of attenuation maps for the system, of the tracking and correction of head motion for addressing this potential source of degradation.

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