Holden Thorp: “Making Drugs Better by Making them Worse”
Robyn Klein: “Learning from viruses: how brain inflammation may cause dementia”
Thorp Abstract: Metalloenzymes comprise a third of all enzymes and are inhibited by 10% of all marketed drugs. Drugs that bind very strongly to metal atoms give tantalizingly high affinities, but are often toxic: the solution lies in going on the road less traveled.
Klein Abstract: People who have experienced brain infections with viruses, such as West Nile virus, often develop severe memory disorders that interfere with daily life functions. Here I will discuss how efficient clearance of virus may lead to changes in brain structure and function.
On the third Thursday of every month , ICTS Precision Medicine hosts a session featuring WashU faculty working in translational genomics/precision medicine areas. Talks are typically oriented toward biotechnology, diagnostics, informatics, start-ups and precision interventions based on medical genomics innovations.
For inquiries contact Sherri Gabbert.