“Bioengineering Approaches to Modulate Stem Cells for Tissue Regeneration”
Hosted by the Institute of Materials Science & Engineering
Abstract: Stem cells hold great therapeutic potential but, to date, have had limited applications in the clinical setting. Although transplantation of stem cells for regeneration of injured/diseased tissues has been extensively studied, several major barriers still remain, including low cell survival rate, poor control of differentiation, slow maturation, and low integration of grafted cells with the host tissue. I will discuss several bioengineering strategies to address these issues, such as improving stem cell survival through hydrogel-mediated formation of neovascular networks at brain lesion sites after traumatic or ischemic injuries, and expediting stem cell maturation through nanoparticle-mediated transcription activation. I will also discuss biomaterials approaches to manipulate endogenous cells for injured/diseased tissue regeneration.
Please note that for all in-person events, attendees must adhere to Washington University’s public health requirements, including the latest events and meetings protocol. Guests will be required to show a successful self-screening result and wear a mask at all times.
For inquiries contact Beth Gartin.