“Ketamine and Nitrous Oxide for Acute Suicidality”

NOTE date

Papers to review:

• “Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Patients Who Have Active Suicidal Ideation With Intent: Double-Blind, Randomized Study (ASPIRE I)” Journal of Clinical Psychiatry (2020)
• “Esketamine Nasal Spray for Rapid Reduction of Depressive Symptoms in Patients With Major Depressive Disorder Who Have Active Suicide Ideation With Intent: Results of a Phase 3, Double-Blind, Randomized Study (ASPIRE II)” Journal of Clinical Psychiatry (2021)

The recent development of novel, fast acting, and durable antidepressant treatments such as Ketamine, Brexanolone, and Psilocybin has disrupted our view of the neuroscience and treatment of mood disorders. The Rapid Antidepressants Journal Club focuses on the research into the basic and translational science of how these drugs work.

Full schedule, Rapid Antidepressants Journal Club

For inquiries contact Joshua Siegel.