Medicine

Research Topics

• Innate immunity in human disease
• Identifying the genetic basis of retinal vasculopathy with cerebral leukodystrophy (RVCL)

Research Topics

• Molecular mechanisms of inflammatory signaling in diseases hallmarked by chronic inflammation

Research Topics

• Chromatin regulation and its role in maintaining tumor initiation cells and normal neural stem cells

Research Topics

• Ischemic stroke
• Platelets
• Neutrophils

Research Topics

• Targeting lysosomal pathway in Alzheimer's disease, amyloid cardiomyopathy
• Regulators of lysosome machinery

Research Topics

• Cellular, Molecular, and Genetic Studies of Cardiac Hypertrophy and Heart Failure

Research Topics

• Brain biology and disease
• Acute and chronic responses to respiratory viruses

Research Topics

• Interactions between the nervous and genitourinary systems during development
• Molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract
• Injury and regeneration using animal models
• Mechanisms of malformations using organoids from iPSCs

Research Topics

• Novel immunotherapeutic strategies to treat solid tumors

Research Topics

• Molecular mechanisms of centriole biogenesis and ciliogenesis

Research Topics

• in vitro production and study of pancreatic insulin-producing β cells from human pluripotent stem cells for use in cellular replacement therapy and drug screening

Research Topics

• Concussion
• Head injury

Research Topics

• Molecular, cellular and systemic mechanisms involved in the dynamic regulation of cardiac and neuronal membrane excitability

Research Topics

• Mechanisms of inflammation from systemic inflammatory disorders in immune-privileged organs (e.g. eye, brain)

Research Topics

• Cellular mechanisms to clear misfolded proteins, and therapies to minimize toxicity by stimulating degradation of misfolded proteins

Research Topics

• Diabetes mellitus

Research Topics

• Understanding the neuroimmune basis of infectious and non-infectious diseases

Research Topics

•  Ion channels as regulators of cellular metabolism

Research Topics

• Pathophysiology and novel therapies for lysosomal storage diseases

Research Topics

• Impact of neuroendocrine signals on bone loss and marrow adiposity in diseases including periodontitis, arthritis, and diabetes

Research Topics

• Examining immune responses against viruses that establish persistent infections in their hosts

Keywords: Wolfram Syndrome, neurodegeneration, optic nerve atrophy

Research Topics

• Role of immune system and nervous system dysfunction in chronic itch conditions, mast cell biology