Pediatric pilocytic astrocytoma (PA) is a common type of low-grade brain tumor in children, influenced by specific genetic changes. Led by David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor of Neurology, researchers at WashU Medicine have conducted a study, published in Genes & Development, using advanced stem cell techniques to investigate the genetic […]
A study in mice by researchers at the School of Medicine indicates that brain injury can lead to brain tumors in susceptible individuals. For this study, they used mice that model people with neurofibromatosis type 1 (NF1), a genetic disorder that causes brain tumors. The study showed that molecules released by injured neurons set off […]
A drug used to treat children with epilepsy prevents brain tumor formation and growth in two mouse models of neurofibromatosis type 1 (NF1), according to a study by researchers at Washington University School of Medicine in St. Louis. NF1 is a genetic condition that causes tumors to grow on nerves throughout the body, including the […]
Four faculty members at Washington University School of Medicine in St. Louis have been elected to the National Academy of Medicine, a part of the National Academy of Sciences. They are Opeolu M. Adeoye, MD; Farshid Guilak, PhD; David H. Gutmann, MD, PhD; and Jonathan Kipnis, PhD. Membership in the academy is considered one of the […]
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor of Neurology at Washington University School of Medicine in St. Louis, has been elected to the Association of American Physicians. Election is an honor extended to physicians who have made outstanding contributions to basic or translational biomedical research and who represent the highest caliber […]
People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign — meaning they don’t spread to other parts of the body and are not considered life-threatening — but they can still cause serious medical problems such as blindness, especially when they form in the brain and nerves. […]
There’s not much good that can be said about asthma, a breathing disease in which the airways become narrowed and inflamed. But there’s this: People with asthma seem to be less likely to develop brain tumors than others. And now, researchers at Washington University School of Medicine in St. Louis believe they have discovered why. […]
Seeing, hearing, thinking, daydreaming — doing anything at all, in fact — activates neurons in the brain. But for people predisposed to developing brain tumors, the ordinary buzzing of their brains could be a problem. A study by researchers at Washington University School of Medicine in St. Louis and Stanford University School of Medicine shows […]
Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital have established the Brain Tumor Center, a multidisciplinary practice of physicians and scientists whose mission is to provide leading-edge, patient-centric care for brain tumor patients while also developing transformative basic, translational and clinical research to develop new therapies and improve patient outcomes. Neurosurgeon and scientist Albert H. Kim, […]
Seven faculty members at Washington University in St. Louis are among 489 new fellows selected by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society. And four of those seven are School of Medicine faculty. The newly selected fellows from the medical school are: Aaron DiAntonio, MD, PhD; David H. Gutmann, […]
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and vice chair for research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, is a recipient of the 2020 Neuro-oncology Scientific Award from the American Academy of Neurology. The award recognizes singular scientific achievement that has advanced […]
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and vice chair for research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, has received the George W. Jacoby Award from the American Neurological Association for his discoveries on the role of the immune system in brain […]
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and vice chair for research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, has received the Advocate of Hope Award from the national Neurofibromatosis (NF) Network. The NF Network is a nonprofit dedicated to helping people living […]
Children with the genetic condition neurofibromatosis type 1 (NF1) can develop brain and nerve tumors. If a tumor develops within the optic nerve, which connects the eye and the brain, the child may lose his or her vision. New research at Washington University School of Medicine in St. Louis indicates that the growth of these […]
Gutmann David Gutmann, MD, PhD, the Donald O. Schnuck Family Professor of Neurology at the School of Medicine, has received a second Einstein Visiting Fellowship from the Berlin Institute of Health to study how immune cells in the brain known as microglia are linked to cancer, vision loss and behavioral problems in the disease neurofibromatosis type […]
David H. Gutmann, MD, PhD, the Donald O. Schnuck Family Professor and vice chair for research affairs in the Department of Neurology at Washington University School of Medicine in St. Louis, has received the Abhijit Guha Award from the Society for Neuro-Oncology and the Section on Tumors of the American Association of Neurological Surgeons/Congress of […]
Tumors arise when cells shake off their restraints and start to multiply out of control. But how fast a tumor grows does not depend solely on how quickly the cancer cells can divide, a new study has found. By examining brain tumors in mice, researchers at Washington University School of Medicine in St. Louis discovered […]
David Gutmann, MD, the Donald O. Schnuck Professor of Neurology at the School of Medicine, has received a three-year, $900,000 grant from the Gilbert Family Foundation to study ways to restore sight to patients with neurofibromatosis type 1. Read more.
Genetically engineered mice mimic common sleep problems From the WashU School of Medicine News… Mice that sleep fitfully could help researchers unravel the mystery of insomnia. Researchers at Washington University School of Medicine in St. Louis studied mice genetically modified to mimic the genetic disease neurofibromatosis type 1 (NF1), which is associated with sleep problems. […]
Analysis of MRI scans identifies some unexplained bright objects as tumors From the WashU Newsroom… The frequency of brain tumors has been underestimated in children with the common genetic syndrome neurofibromatosis type 1 (NF1), according to a new study. This disorder is characterized by birthmarks on the skin and benign nerve tumors that develop in […]