Cavalli, Klyachko receive grant to investigate hypersensitivity in Fragile X syndrome

Valeria Cavalli, PhD, the Robert E. and Louise F. Dunn Professor of Biomedical Research in the Department of Neuroscience at Washington University, has received a grant of more than $400,000 to understand the origins of hypersensitivity in Fragile X syndrome (FXS). This genetic disorder, which accounts for the most cases of autism by a known […]

Protein linked to intellectual disability has complex role

Fragile X syndrome, the leading inherited cause of intellectual disability, is due to a genetic mutation that largely eliminates the fragile X protein, a critical element of normal brain development and function. The fragile X protein modulates neuronal functions, including neurons within the so-called GABAergic system that regulates the activity of neural circuits. The protein’s […]