A new quantitative analysis method for the fish behavior under ammonia nitrogen stress based on pruning strategy
(2025) Aquaculture, 600, art. no. 742192, .
Xu, W., Yu, J., Xiao, Y., Wang, G., Li, X., Li, D.
a National Innovation Center for Digital Fishery, China Agricultural University, Beijing, 100083, China
b Key Laboratory of Intelligent Breeding Technology, Ministry of Agriculture and Rural Areas, China Agriculture University, Beijing, 100083, China
c Beijing Engineering and Technology Research Centre for Internet of Things in Agriculture, China Agriculture University, Beijing, 100083, China
d College of Information and Electrical Engineering, China Agricultural University, Beijing, 100083, China
e McKelvey School of Engineering, Washington University in St. Louis, 63130, MO, United States
Abstract
Ammonia nitrogen, as a “deadly killer” in aquaculture, poses a fatal threat to fish due to its accumulated concentration. Fish usually exhibit different behavior characteristics before and after being subjected to ammonia nitrogen stress. However, the traditional behavior analysis methods have the disadvantages of easy detachment and interfere with the experimental results. Therefore, this paper proposes a two-level fusion model based on pruning strategy to address this problem. Firstly, while ensuring the high accuracy of the object detection model, the pruning strategy is adopted to further eliminate the redundant weights in the model to achieve the model lightweight, which is called LAMP-SAG-YOLOv8. Secondly, the proposed object detection model is integrated with DeepMOT tracker to achieve accurate tracking of multi-object fish in videos and obtain location information. Finally, the anxiety behavior and phototaxis behavior of bass, sturgeon and zebrafish under different ammonia nitrogen stress are quantitatively analyzed, including spatial distribution, swimming distance and behavioral heat map. The experimental results show that the optimized object detection model reduces the number of parameters by 77.75 %, GFLPs by 71.45 %, and increases FPS by 84.06 % compared to the original model. Compared with state-of-the-art trackers, the proposed DeepMOT tracker, which integrates object detection, achieves the multiple object tracking accuracy (MOTA) of 86.25 %, the multiple object tracking precision (MOTP) of 72.21 %, and the identity switch (IDSw) of 12. These results show that the approach could realize the non-contact observation of fish behavior changes under ammonia nitrogen stress, providing a new idea and method for researching abnormal behavior of aquatic animals. © 2025 Elsevier B.V.
Author keywords
DeepMOT; Machine vision; Object tracking; Swimming distance; YOLOv8
Document Type: Article
Publication Stage: Final
Source: Scopus
Early prenatal but not postnatal glucocorticoid exposure is associated with enhanced HPA axis activity into adulthood in a wild primate
(2025) Proceedings of the Royal Society B: Biological Sciences, 292 (2039), art. no. 20242418, .
Anzà, S., Heistermann, M., Ostner, J., Schülke, O.
a Department of Medicine, Infectious Diseases Division, Washington University School of Medicine, St Louis, MO, United States
b Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy
c Behavioral Ecology Department, University of Goettingen, Goettingen, Germany
d Primate Social Evolution Group, German Primate Center, Leibniz Institute for Primate Research, Goettingen, Germany
e Endocrinology Laboratory, German Primate Center, Leibniz Institute for Primate Research, Goettingen, Germany
f Leibniz ScienceCampus Primate Cognition, German Primate Center, Leibniz Institute for Primate Research, Goettingen, Germany
Abstract
The hypothalamic-pituitary-adrenal (HPA) axis plays a dual role in the biology of developmental plasticity in mammals, including humans – HPA axis activity not only provides the input for, but is also a target of, offspring developmental plasticity. To investigate the understudied effects of exposure timing, this study quantified maternal HPA axis activity during each half of gestation as well as during early lactation and assessed its effect on offspring HPA axis activity in a cross-sectional sample of infant, juvenile and adult Assamese macaques (Macaca assamensis). To add ecological validity to experimental studies under laboratory conditions, macaques were studied in the wild. Increased maternal faecal glucocorticoid (GC) metabolite levels experienced early in gestation, but not postnatal exposure during lactation were associated with increased offspring HPA axis activity from infancy into adulthood. Building on prior findings, this study indicates that significant timing effects not only influence the presence, magnitude and direction, but also the consistency of maternal GC effects on offspring HPA axis function. © 2025 The Author(s).
Author keywords
developmental plasticity; maternal effects; sensitive periods; stress response
Document Type: Article
Publication Stage: Final
Source: Scopus
Changes in daily stress reactivity and changes in physical health across 18 years of adulthood
(2025) Annals of Behavioral Medicine, 59 (1), art. no. kaae086, .
Rush, J., Charles, S.T., Willroth, E.C., Cerino, E.S., Piazza, J.R., Almeida, D.M.
a Department of Psychology, University of Victoria, Victoria, V8W 2Y2, BC, Canada
b Department of Psychological Science, University of California, Irvine, Irvine, 92697, CA, United States
c Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, 63130, MO, United States
d Department of Psychological Sciences, Northern Arizona University, Flagstaff, 86011, AZ, United States
e Department of Public Health, California State University, Fullerton, Fullerton, 92831, CA, United States
f Department of Human Development and Family Studies, Pennsylvania State University, University Park, 16803, PA, United States
Abstract
Background: Stress plays a pivotal role in physical health. Although many studies have linked stress reactivity (daily within-person associations between stress exposure and negative affect) to physical health outcomes, we know surprisingly little about how changes in stress reactivity are related to changes in physical health. Purpose: The current study examines how change in stress reactivity over 18 years is related to changes in functional health and chronic health conditions. Methods: Three measurement bursts from the National Study of Daily Experiences (N = 2880; 55% female) each included daily measures of stressor exposure and negative affect across 8 consecutive days, yielding 33 944 days of data across 18 years of adulthood. At each wave, participants reported their functional health limitations (ie, basic activities of daily living [ADL] and instrumental activities of daily living [IADL]) and chronic health conditions. Multilevel structural equation models simultaneously modeled stress reactivity at Level 1, longitudinal changes in stress reactivity at Level 2, and the association between changes in stress reactivity and changes in functional limitations and chronic conditions at Level 3. Results: Higher levels of stress reactivity at baseline were associated with more functional health limitations 18 years later (ADLs: Est. = 0.90, P = .001; IADLs: Est. = 1.78, P < .001). Furthermore, individuals who increased more in their stress reactivity across the 18-year period also showed greater increases in their functional health limitations (ADLs: Est. = 4.02, P = .017; IADLs: Est. = 5.74, P < .001) and chronic conditions (Est. = 11.17, P = .008). Conclusions: These findings highlight the strong connection between health and stress in daily life, and how they travel together across adulthood. © The Author(s) 2024. Published by Oxford University Press on behalf of the Society of Behavioral Medicine.
Author keywords
chronic conditions; daily diary; functional health; multilevel SEM; stressor reactivity
Document Type: Article
Publication Stage: Final
Source: Scopus
Neurodevelopmental and Mental Health Outcomes in a National Clinical Sample of Youth With Sex Chromosome Trisomies Compared With Matched Controls
(2025) Journal of Developmental and Behavioral Pediatrics, art. no. 10.1097/DBP.0000000000001342, .
Hall, A., Furniss, A., Tartaglia, N.N., Janusz, J., Wilson, R., Middleton, C., Martin, S., Frazier, J., Martinez-Chadrom, M., Hansen-Moore, J., Ikomi, C., Ross, J., Vogiaski, M.G., Morrow, L., Christakis, D.A., Lean, R.E., Nokoff, N., Pyle, L., Davis, S.M.
a University of Colorado School of Medicine, Aurora, CO, United States
b University of Colorado, Adult and Child Consortium for Health Outcomes Research and Delivery Sciences (ACCORDS), Aurora, CO, United States
c Extraordinary Kids Clinic and Research Program, Children’s Hospital Colorado, Aurora, CO, United States
d Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States
e Department of Pediatric Psychology, Nationwide Children’s Hospital, Columbus, OH, United States
f Department of Pediatrics, Nemours Children’s Health DE, Wilmington, DE, United States
g Division of Endocrinology, Department of Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, United States
h Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children’s Hospital of Philadelphia, PA, United States
i Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, PA, United States
j Department of Biostatistics and Informatics, University of Colorado School of Public Health, Aurora, CO, United States
k Department of Pediatrics, Seattle Children’s Hospital, Seattle, WA, United States
l Special Olympics International, Washington, DC, United States
m Department of Psychiatry (Child and Adolescent), Washington University School of Medicine, St Louis, MO, United States
Abstract
Objective: To compare the prevalence of neurodevelopmental and mental health diagnoses in a national sample of youth with sex chromosome trisomies (SCTs) with matched controls. Methods: Patients in PEDSnet and a diagnosis code mapping to 47,XXY/Klinefelter syndrome (n = 1171), 47,XYY/Double Y syndrome (n = 243), or 47,XXX/Trisomy X syndrome (n = 262) were matched with controls using propensity scores. Generalized estimating equations computed odds ratios (OR) with 95% confidence intervals (CI) for the prevalence of diagnoses within the neurodevelopmental and mental health composites, psychotropic medication prescriptions, and encounters with behavioral health and therapy providers. Alpha was set at 0.0025 to account for multiple comparisons. Results: Patients with SCTs had higher odds of diagnoses within the neurodevelopmental (OR 6.3, 95% CI, 5.7-7.2) and mental health composites (OR 2.7, 95% CI, 2.3-3.2) compared with matched controls. All neurodevelopmental diagnoses were more prevalent among all SCT groups compared with controls. Within the mental health composite, only the prevalence of anxiety and mood disorder was higher in all SCT groups. A higher proportion of patients with SCTs had psychotropic prescriptions compared with controls (stimulants 13.1% vs 5.2%, selective serotonin reuptake inhibitors 8.7% vs 2.8%, antipsychotics 6.5% vs 2.4%, p < 0.0001 for all). Overall, 48% of patients with SCTs had a clinical encounter with a behavioral health provider vs 16.6% of controls (OR 5.6, 95% CI, 4.1-5.1). Conclusion: Compared with matched controls, youth with SCTs receiving care at US tertiary care pediatric centers have disproportionately high rates of neurodevelopmental and mental health conditions, emphasizing the need for appropriate screening and intervention in these populations. Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.
Author keywords
47,XXX; 47,XXY; 47,XYY; Jacobs syndrome; Klinefelter syndrome; PEDSnet; sex chromosome aneuploidies; Trisomy X
Document Type: Article
Publication Stage: Article in Press
Source: Scopus