Washington University in St. Louis will begin construction in March on what will be one of the largest neuroscience research buildings in the country. Located on the School of Medicine campus, the 11-story, state-of-the-art research facility will merge, cultivate and advance some of the world’s leading neuroscience research. The 609,000-square-foot facility and interconnected projects initially […]
“Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology” (2020) Scientific Reports Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology (2020) Scientific Reports, 10 (1), art. no. 2975, . Shen, X.a , Ma, S.a , Vemuri, P.b , Simon, G.a , Weiner, M.W.c , Aisen, P.d , Petersen, R.b , Jack, C.R.b , Saykin, A.J.e , […]
“Genomic prediction of alcohol-related morbidity and mortality” (2020) Translational Psychiatry Genomic prediction of alcohol-related morbidity and mortality (2020) Translational Psychiatry, 10 (1), art. no. 23, . Kiiskinen, T.a f , Mars, N.J.f , Palviainen, T.f , Koskela, J.f , Rämö, J.T.f , Ripatti, P.f , Ruotsalainen, S.f , Palotie, A.f g h , Madden, P.A.F.b , Rose, R.J.c , Kaprio, J.d […]
’Tis the season for attempted lifestyle changes and vice-forsaking of all sorts. For the more resolute, perhaps a new 2020 goal has really started to stick after two months of hard-fought discipline. Others, particularly many Christians, are just beginning to give something up for Lent, a 40-day period leading up to the celebration of Easter. […]
The American Association for the Advancement of Science (AAAS) has elected Deanna Barch the chair-elect of its Section on Psychology, one of 24 specialized AAAS sections. Barch Barch is professor and chair of psychological and brain sciences in Arts & Sciences at Washington University in St. Louis. She is also the Gregory B. Couch Professor of Psychiatry and professor […]
Death by suicide in children has reached a 30-year high in the United States. During middle and high school, 10% to 15% of kids have thoughts of suicide, according to the Centers for Disease Control and Prevention. How early in a child’s life do these thoughts begin? New research from Washington University in St. Louis […]
The Association for Psychological Science (APS) has named Thomas Rodebaugh an APS Fellow. Rodebaugh is professor of psychological and brain sciences and director of clinical training for that department in Arts & Sciences at Washington University in St. Louis. The association awards fellow status to members who have made sustained and outstanding contributions to the science of psychology in […]
Lawrence H. Snyder, MD, PhD, professor of neuroscience at the School of Medicine and of psychological and brain sciences in Arts & Sciences, received a five-year $2.55 million grant from the National Eye Institute of the National Institutes of Health (NIH) for research titled “Interhemispheric communication underlying bimanual and eye-hand coordination.” Read more.
Kristin Van Engen studies the dynamic back-and-forth between communicators, including the impact that noise and accent have on intelligibility and comprehension. Communication among people with different accents is particularly challenging because of the way that our brains expect to hear sounds. People don’t always hear the comfortable sounds they have learned to expect, leading some […]
At the Washington University in St. Louis Board of Trustees meeting Dec. 6, several faculty members were appointed or promoted with tenure, effective Jan. 1 unless otherwise indicated. Appointment with tenure Lisa Tabor Connor as professor of occupational therapy at the School of Medicine, effective Dec. 6; Richard J. Cote, MD, as professor of pathology and immunology […]
Lawrence H. Snyder, MD, PhD, professor of neuroscience at the School of Medicine and of psychological and brain sciences in Arts & Sciences, received a five-year $2.55 million grant from the National Eye Institute of the National Institutes of Health (NIH) for research titled “Interhemispheric communication underlying bimanual and eye-hand coordination.” Read more.
Wouter Kool, assistant professor of psychological and brain sciences in Arts & Sciences at Washington University in St. Louis, was named a “Rising Star” by the Association for Psychological Science (APS), the leading international organization dedicated to advancing scientific psychology across disciplinary and geographic borders. Kool’s research explores the interaction between cognitive control, decision-making and reinforcement learning. […]
The TV show “Survivor,” now in its 39th season, has spawned hosts of spin-offs and adaptations. Most cater to reality-TV lovers worldwide, but one surprising variation has become part of the toolbox researchers use to understand the effects of bullying on adolescents. Bullying is known to be a risk factor for depression, especially among young […]
Beverly Wendland, the James B. Knapp Dean of the Krieger School of Arts & Sciences at Johns Hopkins University, has been appointed provost of Washington University in St. Louis, effective July 1, according to Chancellor Andrew D. Martin. Wendland will succeed Marion Crain, who has served as interim provost since July 2019. A member of the Johns […]
Every day, social service professionals tackle complex problems across varying domains, working to determine which interventions are likely to be effective, fair and within an agency’s capabilities. For a struggling parent in danger of losing their home, which alternative would prove more helpful in the long run, housing assistance or job training? Might a child […]
We have many ways of marking the passage of time. Saturday’s Winter Solstice, which marks not just the arbitrary beginning of a season, but also the slow return of daylight to the Northern hemisphere. Or the coming decade, as many reflect back on everything that’s happened since 2010, and prepare to mark the beginning of […]
James DuBois believes in second chances. DuBois, DSc, PhD, the Steven J. Bander Professor of Medical Ethics and Professionalism at Washington University School of Medicine in St. Louis, founded the first national training program for researchers who have had lapses in laboratory compliance or research ethics, providing strategies and resources to help them get back […]
The Russell Sage Foundation has awarded Calvin Lai, assistant professor of psychological and brain sciences in Arts & Sciences, $127,015 for a randomized controlled trial aimed at addressing the gap between the aims and outcomes of implicit bias training in police departments. The project, titled “Improving Police-Community Relations with a Social-Psychological Intervention for Reducing Racial Bias in Policing initiative,” will allow […]
“The impact of dopamine D2-like agonist/antagonist on (18F)VAT PET measurement of VAChT in the brain of nonhuman primates” (2020) European Journal of Pharmaceutical Sciences The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates (2020) European Journal of Pharmaceutical Sciences, 143, art. no. 105152, . Liu, H.a , Luo, Z.a , Gu, […]
Erik Herzog is a chronobiologist at Washington University, studying the molecules, cells and circuits that underlie daily rhythms in physiology and behavior. He was recently named the Viktor Hamburger Professor of Biology. Viktor Hamburger was one of the most influential neuro-embryologists of the twentieth century, beginning his research at Wash U in 1935. “I am deeply […]
“Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear” (2020) Hearing Research Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear (2020) Hearing Research, 385, art. no. 107839, . Wan, L.a , Lovett, M.b , Warchol, M.E.c , Stone, J.S.a a Virginia Merrill Bloedel Hearing […]
“A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease” (2020) Neurobiology of Disease A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease (2020) Neurobiology of Disease, 134, art. no. 104647, . Aflaki, E.a , Stubblefield, B.K.a , McGlinchey, R.P.b , McMahon, B.a , Ory, D.S.c , Sidransky, E.a a Section of Molecular Neurogenetics, National Human Genome Research […]
“Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems” (2020) Bone Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems (2020) Bone, 130, art. no. 115144, . Maximova, N.a , Zennaro, F.b , Gregori, M.a , Boz, G.c , Zanon, […]
The WUSTL Neuroscience Pipeline program prepares undergraduates from diverse backgrounds for neuroscience PhD programs. With support from the NIH Blueprint ENDURE Program and WUSTL, accepted students are funded for up to two 10-week summers. The program combines independent research and a rigorous summer curriculum of courses and workshops that focus on building a foundation in […]
“Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis” (2019) Journal of Anxiety Disorders Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis (2019) Journal of […]
At the Washington University in St. Louis Board of Trustees meeting Oct. 4, more than a dozen faculty members were appointed or promoted with tenure or granted tenure, effective Oct. 4 unless otherwise indicated. Appointment with tenure Flora Cassen as associate professor of Jewish, Islamic and Middle Eastern studies and of history in Arts & Sciences; […]
“Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction” (2020) Early Human Development Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction (2020) Early Human Development, 140, art. no. 104891, . Whitehead, H.V.a , Vesoulis, Z.A.a , Maheshwari, A.b , Rambhia, A.a , Mathur, A.M.c a Department of Pediatrics, Division of […]
Never again. After we turn back the clocks one hour on the morning of Nov. 3, Washington University in St. Louis chronobiologist Erik Herzog wants us to just keep it that way. Herzog “Just lock it in,” Herzog said. “Forever.” Herzog is a professor of biology in Arts & Sciences and president of the Society for Research on […]
For years, researchers have observed that alcohol consumption is associated with reduced brain volume and concluded that drinking can literally shrink the brain. But new research turns that theory on its head, suggesting that reduced brain volume may represent a genetically-conferred predispositional risk factor for heavier alcohol consumption. “Our results suggest that associations between alcohol […]
Dear Colleagues, We are delighted to announce that Jeanne Velders has accepted the position of IRB Executive Director of the Human Research Protection Office (HRPO) at Washington University. Jeanne has been serving as the Interim Executive Director for HRPO following Martha Jones’ departure this past July. In her new role, Jeanne will be responsible for […]
“Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex” (2020) Neurobiology of Disease Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex (2020) Neurobiology of Disease, 134, art. no. 104615, . Zhang, B.a , Guo, D.a , Han, L.a , […]
Location: St. Louis, Missouri, U.S. Neuroscience Program Global rank: 9 Best Global Universities overall rank: 31 Fact: Washington University in St. Louis is home to a wide array of research centers related to neuroscience, including the Hope Center for Neurological Disorders, the Charles F. and Joanne Knight Alzheimer Disease Research Center and the McDonnell Center for Systems Neuroscience. Neuroscience […]
“Identifying reproducible individual differences in childhood functional brain networks: An ABCD study” (2019) Developmental Cognitive Neuroscience Identifying reproducible individual differences in childhood functional brain networks: An ABCD study (2019) Developmental Cognitive Neuroscience, 40, art. no. 100706, . Marek, S.a , Tervo-Clemmens, B.b , Nielsen, A.N.c , Wheelock, M.D.a , Miller, R.L.d , Laumann, T.O.a , Earl, E.f , Foran, W.W.e […]
Keith Hengen, assistant professor of biology in Arts & Sciences, received a McKnight Scholar Award from the McKnight Foundation. The award supports neuroscientists in the early stages of their careers who are focusing on disorders of learning and memory. Read more.
“Alzheimer Disease: An Update on Pathobiology and Treatment Strategies” (2019) Cell Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019) Cell, 179 (2), pp. 312-339. Long, J.M., Holtzman, D.M. Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, United States Abstract Long […]
Researchers long wondered how the billions of independent neurons in the brain come together to reliably build a biological machine that easily beats the most advanced computers. All of those tiny interactions appear to be tied to something that guarantees an impressive computational capacity. Over the past 20 years, evidence mounted in support of a […]
“Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers” (2019) Neurobiology of Aging Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers (2019) Neurobiology of Aging, 83, pp. 54-62. Chen, Q.a b , Boeve, B.F.c , Schwarz, C.G.b , Reid, R.b , Tosakulwong, N.d , Lesnick, T.G.d , Bove, J.e , Brannelly, P.f , Brushaber, […]
Many thanks to all who participated in this year’s Neuroscience Retreat. Graduate student and post doc presenters at the Retreat were eligible for the Thach Award competition. Congratulations to the 2019 Thach Award winners: Short Talks: Yang Shi, PhD (Holtzman lab, WashU Neurology) “Microglia drive neurodegeneration and mediate APOE’s effect on neurodegeneration in a tauopathy mouse […]
“The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability” (2019) NeuroImage The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability (2019) NeuroImage, 202, art. no. 115990, . Betzel, R.F.a b c , Bertolero, M.A.a , Gordon, E.M.d e , Gratton, C.f g , Dosenbach, N.U.F.f h i , […]
Obesity researchers from around Missouri, led by scientists at Washington University School of Medicine in St. Louis, have received a grant to help evaluate and put in place family-focused weight-management programs designed to reduce childhood obesity, particularly among children from low-income families. With a five-year, $3.7 million grant from the Centers for Disease Control and […]
Too much physical exertion appears to make the brain tired. That’s the conclusion of a study of triathletes published Thursday in the journal Current Biology. Researchers found that after several weeks of overtraining, athletes became more likely to choose immediate gratification over long-term rewards. At the same time, brain scans showed the athletes had decreased activity in an […]
Meredith Jackrel, assistant professor of chemistry in Arts & Sciences, received a $300,000 grant from the ALS Association to support a project titled “Countering the aggregation of TDP-43, FUS, DPRS, and Matrin 3 with engineered protein disaggregases.” Read more.
“Pioglitazone improves working memory performance when administered in chronic TBI” (2019) Neurobiology of Disease Pioglitazone improves working memory performance when administered in chronic TBI (2019) Neurobiology of Disease, 132, art. no. 104611, . McGuire, J.L.a , Correll, E.A.a , Lowery, A.C.b , Rhame, K.c , Anwar, F.N.d , McCullumsmith, R.E.e , Ngwenya, L.B.a f a Department of Neurosurgery, University of Cincinnati, […]
Ryan Bogdan, associate professor of psychological and brain sciences in Arts & Sciences, received a two-year, $264,938 grant from the National Institutes of Health (NIH) to study the effects of alcohol on the maturing brain. The study will look at genome-wide association studies to longitudinal neuroimaging studies of adolescents and young adults in order to […]
“Large posttraumatic stress disorder improvement and antidepressant medication adherence” (2020) Journal of Affective Disorders Large posttraumatic stress disorder improvement and antidepressant medication adherence (2020) Journal of Affective Disorders, 260, pp. 119-123. Salas, J.a b , Scherrer, J.F.a b , Tuerk, P.c , van den Berk-Clark, C.a , Chard, K.M.d , Schneider, F.D.e , Schnurr, P.P.f , Friedman, M.J.f , […]
“Alternative ecological strategies lead to avian brain size bimodality in variable habitats” (2019) Nature Communications Alternative ecological strategies lead to avian brain size bimodality in variable habitats (2019) Nature Communications, 10 (1), art. no. 3818, . Fristoe, T.S.a b , Botero, C.A.b a Department of Biology, University of Konstanz, Universitätsstraße 10, Konstanz, 78464, Germany b Department of Biology, Washington University in St. Louis, […]
Dear Colleagues, I am pleased to announce that Dr. Cindy Brantmeier has been selected to serve as the first Faculty Fellow in International Research for the School of Medicine and Danforth Campus. The Faculty Fellow in International Research will advise faculty on conducting international research and achieving effective collaborations with international partners that are compliant […]
Researchers expect this massive endeavor, receiving $30 million in federal funding per year, will transform our understanding of brain development. Neuroscientists are positively giddy about ABCD, and for good reason: It is larger and more racially and socioeconomically diverse than any comparable study to date. “We’re going to be working with this dataset for decades,” […]
“Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter” (2019) Scientific Reports Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter (2019) Scientific Reports, 9 (1), art. no. 12246, . Fukutomi, H.a b , Glasser, M.F.c d , Murata, K.e , […]
"Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex" (2019) Scientific Reports Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex(2019) Scientific Reports, 9 (1), art. no. 11700, . Maranesi, M.a , Bruni, S.a b , Livi, A.a c , Donnarumma, F.d , Pezzulo, G.d , Bonini, L.a a Department of Medicine […]