Poverty negatively impacts structural wiring in children’s brains, study indicates

A new study from Washington University School of Medicine in St. Louis suggests that growing up in poverty may influence the wiring of a child’s brain. The study, published June 27 in JAMA Network Open, indicates a link between both neighborhood and household poverty and the brain’s white matter tracts, which allow for communication between […]

Quinn awarded grant to compare neurotropic markers in human and primate milk

A new Leakey Foundation award will support research to better understand how certain hormones in breast milk contribute to brain growth in humans and primates. E.A. Quinn, PhD, associate professor of biological anthropology, has received a grant from the Leakey Foundation to study how neurotropic hormones in human and primate milk affect brain growth. Humans have very […]

Children’s brain scans provide clues to processing of emotional cues

Children with specific psychiatric symptoms, such as anxiety, may struggle to understand emotional cues when people around them are happy, sad or angry, and that lack of understanding can make it difficult to respond appropriately in social situations. Studying brain scans from hundreds of children ages 5 to 15, researchers at Washington University School of […]

Rogers, Smyser awarded MERIT grant for research on preterm babies

Researchers in child psychiatry and pediatric neurology at Washington University School of Medicine in St. Louis have been named recipients of a prestigious MERIT award from the National Institute of Mental Health of the National Institutes of Health (NIH) to support their research focused on preterm babies’ brains as the children age. The MERIT (Method […]

WashU research spurs changes to global guidelines for feeding malnourished kids

The brain health of millions of malnourished children stands to benefit following changes to global guidelines for the formulation of ready-to-eat therapeutic food — the standard treatment for severe malnutrition in developing countries. Results of a major clinical trial in Africa led by Mark Manary, MD, a professor of pediatrics at Washington University School of Medicine in […]

Kamilov awarded second Scialog grant

Ulugbek Kamilov, PhD, assistant professor of electrical and systems engineering and of computer science at Washington University in St. Louis’ McKelvey School of Engineering, is among 21 early-career researchers awarded funding in the second year of Scialog: Advancing Bioimaging. The project is supported by the Research Corporation for Science Advancement, the Chan Zuckerberg Initiative, the […]

Rogers named director of child psychiatry division

Cynthia E. Rogers, MD, has been named the new Blanche F. Ittleson Professor of Psychiatry and director of the William Greenleaf Eliot Division of Child & Adolescent Psychiatry at Washington University School of Medicine in St. Louis. Her appointment was announced by Eric J. Lenze, MD, the Wallace and Lucille Renard Professor and head of the Department of […]

SSRI use during pregnancy not related to childhood depression

In one of the first studies to look at the association between selective serotonin reuptake inhibitors (SSRI) medications and brain development in young children, research from the Behavioral Research and Imaging Neurogenetics (BRAIN)Lab at Washington University in St. Louis found no association between children’s exposure to the drugs in the womb and later childhood depression.  The study […]

Poverty, crime linked to differences in newborns’ brains

Poverty and crime can have devastating effects on a child’s health. But a new study from researchers at Washington University School of Medicine in St. Louis suggests that some environmental factors influence the structure and function of young brains even before babies make their entrances into the world. A study published online April 12 in […]

Gift to help SLCH, WashU develop care model to improve kids’ behavioral health

St. Louis Children’s Hospital and Washington University School of Medicine in St. Louis are tackling the issue of behavioral health support that has emerged as a leading health concern in our country — for people of all ages. The challenges of the COVID-19 pandemic have revealed the number of children suffering and how few resources are […]

Prenatal, early-life influences on child brain development focus of new study

Researchers at Washington University School of Medicine in St. Louis are joining scientists at 24 other sites around the country to conduct a comprehensive study aimed at understanding how prenatal factors and early life experiences influence brain development and behavior in infants and young children. With more than $37 million in funding from several institutes […]

Persistent, distressing psychotic-like experiences associated with impairment in youth

In a new study, researchers examined the association between distressing and persistent psychotic-like experiences (PLEs) in youth and important risk factors for psychopathology. The researchers found that youth who indicate they have persistent, distressing PLEs show impairment in a variety of areas such as cognition and reported psychopathology, highlighting the long-term challenges these children may […]

Enhanced therapeutic foods improve cognition in malnourished children

A nutritional supplement popular in the U.S. and added to some types of yogurt, milk and infant formula can significantly improve cognition in severely malnourished children, according to a study led by researchers at Washington University School of Medicine in St. Louis. The researchers found that when the omega-3 fatty acid known as docosahexaenoic acid […]

17-year study of children associates poverty with smaller, slower-growing subcortical regions

Children in poverty are more likely to have cognitive and behavioral difficulties than their better-off peers. Plenty of past research has looked into the physical effects of childhood poverty, or documented mental health disparities between socioeconomic classes. But Deanna Barch, chair and professor in the Department of Psychological & Brain Sciences in Arts & Sciences at […]

Specific bacteria help explain stunted growth in malnourished children

Many children treated for childhood malnutrition in developing countries never fully recover. They suffer from stunted growth, immune system dysfunction and poor cognitive development that typically cause long-term health issues into adulthood. Now, new research from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research involving malnourished children […]

4 Ways to Help if Your Kid Is Depressed

A couple of weeks ago, I noticed a worrying shift in my 9-year-old. His characteristic silliness — his goofy giggles and incessant bad jokes — had disappeared. He stopped wanting to go outside and said he was too tired to play. He crawled under his bed covers and lay quietly in his room, while the […]

$13.7 million to further adolescent brain development study

Washington University scientists will receive $13.7 million in additional funding for ongoing research into adolescent brain development. Their work is part of the largest long-term study of brain development ever conducted in the United States. Washington University is one of 21 study sites around the country participating in the project. Launched in 2015, the Adolescent Brain […]

Brown School researchers awarded $3.2 million grant to study child growth, development in Haiti

Trish Kohl and Lora Iannotti, associate professors at the Brown School at Washington University in St. Louis, have received a five-year $3.2 million grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health to study stunted growth and development in children in Haiti. “Recent estimates show 250 […]

Potential biomarker for autism identified in infants

Researchers at Washington University School of Medicine in St. Louis and Stanford University have identified a biomarker in newborns that may signal autism spectrum disorder months or even years before troubling symptoms develop and such diagnoses typically are made. The researchers found that babies diagnosed with autism later in childhood had in their cerebrospinal fluid, […]

Brain and Behavior Research Foundation awards grants to five researchers

Five researchers at Washington University School of Medicine in St. Louis have received Young Investigators Grants from the Brain and Behavior Research Foundation. The foundation is committed to alleviating the suffering caused by mental illness by supporting research that will lead to advances and breakthroughs in scientific research. The $70,000 grants help junior investigators launch […]

Why Zika virus caused most harmful brain damage to Brazilian newborns

Due to Zika virus, more than 1,600 babies were born in Brazil with microcephaly, or abnormally small heads, from September 2015 through April 2016. The epidemic took health professionals by surprise because the virus had been known since 1947 and was not linked to birth defects. As scientists scrambled to figure out what was going […]

Suicidal thoughts in 9- and 10-year-olds correlate to family dynamics, study found

Death by suicide in children has reached a 30-year high in the United States. During middle and high school, 10% to 15% of kids have thoughts of suicide, according to the Centers for Disease Control and Prevention. How early in a child’s life do these thoughts begin? New research from Washington University in St. Louis […]

The bullied brain

The TV show “Survivor,” now in its 39th season, has spawned hosts of spin-offs and adaptations. Most cater to reality-TV lovers worldwide, but one surprising variation has become part of the toolbox researchers use to understand the effects of bullying on adolescents. Bullying is known to be a risk factor for depression, especially among young […]

Nature vs. nurture

Compelled by the potential to improve the lives of vulnerable children, emeritus trustee Walter Metcalfe and his wife, Cynthia, have committed nearly $4 million through outright and estate gifts to support the work of Joan L. Luby, MD, a highly regarded child psychiatrist. Luby and her colleagues have linked adversity, including poverty and neglect in the […]

Vogel-Hammen receives award for research in child, adolescent psychiatry

Alecia Vogel-Hammen, MD, PhD, an instructor in child psychiatry at Washington University School of Medicine in St. Louis, has received the American Academy of Child & Adolescent Psychiatry’s 2019 Pilot Research Award for Attention Disorders. The award, supported by the academy’s Elaine Schlosser Lewis Fund, provides up to $15,000 in funding to junior faculty and […]

Human gut microbes could make processed foods healthier

A new study from Washington University School of Medicine in St. Louis sheds light on how human gut microbes break down processed foods — especially potentially harmful chemical changes often produced during modern food manufacturing processes. Eating processed foods such as breads, cereals and sodas is associated with negative health effects, including insulin resistance and […]

Childhood obesity in low-income Missouri families aim of CDC grant

Obesity researchers from around Missouri, led by scientists at Washington University School of Medicine in St. Louis, have received a grant to help evaluate and put in place family-focused weight-management programs designed to reduce childhood obesity, particularly among children from low-income families. With a five-year, $3.7 million grant from the Centers for Disease Control and […]

Brain Scans, Saliva Tests, and Baby Teeth: Inside the Massive, Government-Funded Effort to Understand How Kids’ Brains Develop

Researchers expect this massive endeavor, receiving $30 million in federal funding per year, will transform our understanding of brain development. Neuroscientists are positively giddy about ABCD, and for good reason: It is larger and more racially and socioeconomically diverse than any comparable study to date. “We’re going to be working with this dataset for decades,” […]

$785K NIMH grant awarded to Brown School’s Mary McKay

Mary McKay, the Neidorff Family and Centene Corporation Dean of the Brown School, has received a five-year, $785,000 grant from the National Institutes of Health (NIH)’s National Institute of Mental Health for a project titled “Navigating Resource-Constrained Systems and Communities to Promote the Behavioral Health of Black Youth.” Sean Joe, the Benjamin E. Youngdahl Professor of Social Development […]

Stable home lives improve prospects for preemies

As they grow and develop, children who were born at least 10 weeks before their due dates are at risk for attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder and anxiety disorders. They also have a higher risk than children who were full-term babies for other neurodevelopmental issues, including cognitive problems, language difficulties and motor delays. Researchers […]

A Mix Of These Foods Could Restore Healthy Microbes In Malnourished Kids

When children suffer from severe malnourishment, they don’t just lose weight. The condition wreaks havoc on biological systems throughout the body — including the microbiome, the healthy bacteria and other microbes that live in our digestive tracts. Those bacteria number in the trillions in every person and include hundreds of different species. They’re essential for […]

For malnourished children, new therapeutic food boosts gut microbes, healthy development

A new type of therapeutic food, specifically designed to repair the gut microbiomes of malnourished children, is superior to standard therapy in an initial clinical trial conducted in Bangladesh. An interdisciplinary team of investigators from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, have […]

Metcalfe gift supports study of adversity’s effects on children’s brains

Compelled by the potential to improve the lives of vulnerable children, emeritus trustee Walter Metcalfe Jr. and his wife, Cynthia, have made a commitment of nearly $4 million through outright and estate gifts to support the work of Joan L. Luby, MD, a highly regarded child psychiatrist at Washington University School of Medicine in St. […]

E3 Nutrition Lab Links Child Nutrition, Economics and Evolution

A transdisciplinary laboratory at the Brown School is undertaking research across the world to address “hidden hunger”— poverty-related nutritional deficiencies in mothers and young children. The founder and director of the E3 Nutrition Lab is Lora Iannotti, associate professor and associate dean for public health. The three “E”s represent the lab’s principles for nutrition interventions: […]

Cannabis during pregnancy bumps psychosis risk in offspring

Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis. Fine “Our research shows that prenatal marijuana exposure after maternal knowledge of pregnancy is associated with a small increase in psychosis proneness during middle childhood or about […]

How team sports change a child’s brain

Adult depression has long been associated with shrinkage of the hippocampus, a brain region that plays an important role in memory and response to stress. Now, new research from Washington University in St. Louis has linked participation in team sports to larger hippocampal volumes in children and less depression in boys ages 9 to 11. […]

Wash U Researchers Discuss Latest Findings About Suicidal Ideation Among Children, Young People

A study released this week by the National Institutes of Health indicates that nearly one-third of Americans between the ages of 10 and 12 “screened positive for suicide risk in emergency department settings.” Meanwhile, researchers at Washington University School of Medicine have been studying even younger children who think and talk about suicide – and their […]

Young kids with suicidal thoughts understand concept of death

Depressed children ages 4 to 6 who think and talk about committing suicide understand what it means to die better than other kids, according to new research at Washington University School of Medicine in St. Louis. Such children with suicidal thoughts and words — what psychiatrists call suicidal ideation — were more than three times […]

Scholars highlight impact of early adversity on developing brain, implications for criminal justice

From NPR’s St. Louis Public Radio… The early development of the human brain begins in utero and continues into a person’s early-to-mid-20s. In that time, various environmental factors such as poverty, toxins and violence can influence that development. Among adolescent youth, who are susceptible to engaging in risky behavior, the impact of such stressors can […]

Repetitive behaviors tied to brain activity patterns in toddlers

From Spectrum News… Children who have repetitive behaviors, a core autism trait, show particular patterns of brain activity as early as 1 year of age, according to a new study1. Autistic people have brain activity patterns that differ from those of their typical peers. These differences emerge early in life: A study last year showed […]

Addressing racial disparity in autism outcomes, Washington University seeks to improve diagnosis and intervention for black children

From the St. Louis American… The Center for Disease Control’s Autism and Developmental Disabilities Monitoring Network most recently reported that 1 in 59 children, or about 1.7 percent, have an autism spectrum disorder. Historically, African-American children have being identified with autism spectrum disorder at a significantly lower rate than Caucasian children, but this gap has […]

More pregnant women in U.S. smoking pot

From Reuters… Even as alcohol and tobacco use continue to decline among pregnant women in the U.S., a new study offers fresh evidence that more American mothers are using cannabis during pregnancy. Other recent studies have also documented a rise in cannabis use among pregnant women of all ages, with some evidence of particularly sharp […]

Following tragedy, St. Louis hospitals renew commitment to postpartum mental health

From the St. Louis Post-Dispatch… While pregnant with her fourth baby, Jerrika Massey felt depressed because her father died before he could meet his newest grandchild. He had always been there for her previous births. Massey didn’t tell anyone she was struggling because “I thought it was something I could handle by myself,” she said. […]

New child maltreatment research center launched with $6.5 million NIH grant

Multidisciplinary center includes Constantino’s research on newborns From the WashU Newsroom… Melissa Jonson-Reid, the Ralph and Muriel Pumphrey Professor of Social Work Research at the Brown School, and her team, including faculty from several disciplines across Washington University in St. Louis and Saint Louis University, have received a five-year, $6,496,050 grant from the National Institutes of Health […]

Diagnosing Depression in Young Kids is Harder, Incredibly Important

Experts agree that preschoolers are entirely capable of suffering from clinical depression. And that this depression is not always the result of abuse or neglect. From Fatherly… Until he began doodling bloody pictures of bleeding necks, April Lisbon wasn’t worried about the mental health of her four-year-old student. As a psychologist working with young children […]

How bacteria can save children’s lives

A ground-breaking new project in Bangladesh could help reduce the life-long health problems that come from childhood malnourishment – by focusing on the gut. From BBC – Future… For decades, undernourished infants across the world have been treated with a course of high-calorie, high-protein rich foods. The foods may come in various forms – from […]

Perfectionism in young children may indicate OCD risk

Study involving behavior, brain scans may help ID issues early in life From the WashU School of Medicine News… Studying young children, researchers at Washington University School of Medicine in St. Louis found that kids who possess tendencies toward perfectionism and excessive self-control are twice as likely as other children to develop obsessive-compulsive disorder (OCD) […]

Barch receives $3.5 million for research on brain, mental illness

From the WashU Newsroom… Mental health researcher Deanna Barch, of Washington University in St. Louis, has been awarded a $3.5 million MERIT award from the National Institute of Mental Health, part of the National Institutes of Health (NIH). Barch Barch is chair of the Department of Psychological & Brain Sciences in Arts & Sciences and the Gregory […]

Parent-child therapy helps young children with depression

Early intervention supports kids in processing emotions From the WashU School of Medicine News… Children as young as 3 can be clinically depressed, and often that depression recurs as kids get older and go to school. It also can reappear during adolescence and throughout life. But new research from Washington University School of Medicine in […]