“Impact of intrauterine fetal resuscitation with oxygen on oxidative stress in the developing rat brain” (2021) Scientific Reports Impact of intrauterine fetal resuscitation with oxygen on oxidative stress in the developing rat brain (2021) Scientific Reports, 11 (1), art. no. 9798, . Jiang, J.a d , Giri, T.a , Raghuraman, N.b , Cahill, A.G.c , Palanisamy, A.a b a Department of Anesthesiology, Washington University School of Medicine, St. […]
Category: Brown School
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“Lack of observed tolerance to diazepam nasal spray (Valtoco®) after long-term rescue therapy in patients with epilepsy: Interim results from a phase 3, open-label, repeat-dose safety study” (2021) Epilepsy and Behavior Lack of observed tolerance to diazepam nasal spray (Valtoco®) after long-term rescue therapy in patients with epilepsy: Interim results from a phase 3, open-label, […]
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“New guidance to seekers of autism biomarkers: an update from studies of identical twins” (2021) Molecular Autism New guidance to seekers of autism biomarkers: an update from studies of identical twins (2021) Molecular Autism, 12 (1), art. no. 28, . Constantino, J.N. Department of Psychiatry, Washington University in St. Louis, 660 S Euclid Ave, Campus Box 8504, St. Louis, MO 63110, […]
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“White matter microstructure associations with episodic memory in adults with Down syndrome: a tract-based spatial statistics study” (2021) Journal of Neurodevelopmental Disorders White matter microstructure associations with episodic memory in adults with Down syndrome: a tract-based spatial statistics study (2021) Journal of Neurodevelopmental Disorders, 13 (1), art. no. 17, . Bazydlo, A.a , Zammit, M.a , Wu, M.b , Dean, D.a c , Johnson, S.a c d , Tudorascu, […]
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“Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease” (2021) BMC Neurology Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease (2021) BMC Neurology, 21 (1), art. no. 154, . Gregori-Pla, C.a , Mesquita, R.C.b , Favilla, C.G.c , Busch, D.R.d , Blanco, […]
How racial violence affects Black Americans’ mental health
Black Americans experience an increase in poor mental health days during weeks when two or more incidents of anti-Black violence occur and when national interest surrounding the events is higher, according to a new study involving a researcher at Washington University in St. Louis. Previous research has shown that experiencing racism, even vicariously, can harm […]
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"Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma" (2021) Acta Neuropathologica Communications Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma(2021) Acta Neuropathologica Communications, 9 (1), art. no. 61, . Schieffer, K.M.a , Feldman, A.Z.b , Kautto, E.A.a , […]
Board grants faculty appointments, promotions, tenure
At the Washington University in St. Louis Board of Trustees meeting March 5, numerous faculty members were appointed or promoted with tenure or granted tenure, effective July 1 unless otherwise indicated. Promotion with tenure Ruopeng An to associate professor at the Brown School; Arpita Bose to associate professor of biology in Arts & Sciences; Hong […]
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"TDP-43 and PINK1 mediate CHCHD10 S59L mutation–induced defects in Drosophila and in vitro" (2021) Nature Communications TDP-43 and PINK1 mediate CHCHD10 S59L mutation–induced defects in Drosophila and in vitro(2021) Nature Communications, 12 (1), art. no. 1924, . Baek, M.a , Choe, Y.-J.a , Bannwarth, S.b , Kim, J.H.a , Maitra, S.a , Dorn, G.W., IIc , Taylor, J.P.d , Paquis-Flucklinger, V.b , Kim, N.C.a a Department of Pharmacy Practice and Pharmaceutical […]
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“Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders” (2021) Journal of Neurodevelopmental Disorders Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders (2021) Journal of Neurodevelopmental Disorders, 13 (1), art. no. 10, . Rahn, R.M.a b c , Weichselbaum, C.T.a b d , Gutmann, D.H.d e , Dougherty, J.D.a b d , Maloney, S.E.b d a Department of Genetics, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO […]
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“The transcriptional landscape of Shh medulloblastoma” (2021) Nature Communications The transcriptional landscape of Shh medulloblastoma (2021) Nature Communications, 12 (1), art. no. 1749, . Skowron, P.a b c , Farooq, H.a b c , Cavalli, F.M.G.a c , Morrissy, A.S.d e f , Ly, M.a b c , Hendrikse, L.D.a c g , Wang, E.Y.a c g , Djambazian, H.h i , Zhu, H.g j , Mungall, K.L.k , Trinh, Q.M.j , Zheng, T.l , Dai, S.m , Stucklin, A.S.G.a c , Vladoiu, M.C.a b c , Fong, V.a c , Holgado, B.L.a c , Nor, C.a c , Wu, […]
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“Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis” (2021) Acta Neuropathologica Communications Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis (2021) Acta Neuropathologica Communications, 9 (1), art. no. 40, . Celorrio, M.a , Abellanas, M.A.a c d , Rhodes, J.a , Goodwin, V.a , Moritz, J.a , Vadivelu, S.a , Wang, L.b , Rodgers, R.b , Xiao, S.a , Anabayan, […]
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"Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus" (2021) Communications Biology Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus(2021) Communications Biology, 4 (1), art. no. 260, . Jansson, D.a b c , Dieriks, V.B.b d , Rustenhoven, J.e f , Smyth, L.C.D.g h , Scotter, E.a b , Aalderink, M.a b , Feng, S.a b , Johnson, R.a b , Schweder, P.i , Mee, E.i , Heppner, P.j , Turner, C.k , Curtis, M.b d , […]
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“Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel” (2021) Nature Communications Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel (2021) Nature Communications, 12 (1), art. no. 926, . Arnold, W.R.a , Carnevale, L.N.a , Xie, Z.b , Baylon, J.L.c , Tajkhorshid, E.c , Hu, H.b , Das, A.d e a Department of Biochemistry, University of Illinois Urbana-Champaign, […]
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“A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors” (2021) Scientific Reports A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors (2021) Scientific Reports, 11 (1), art. no. 3858, . Mattar, P.a f g , Jolicoeur, C.a , Dang, T.f g , Shah, S.f g , Clark, B.S.b c , Cayouette, M.a d e a Cellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, QC H2W 1R7, Canada b John […]
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“Domain-general cognitive motivation: evidence from economic decision-making” (2021) Cognitive Research: Principles and Implications Domain-general cognitive motivation: evidence from economic decision-making (2021) Cognitive Research: Principles and Implications, 6 (1), art. no. 4, . Crawford, J.L.a , Eisenstein, S.A.b c , Peelle, J.E.d , Braver, T.S.a a Department of Psychological and Brain Sciences, Washington University in St. Louis, 1 Brookings Dr, Box 1125, St. Louis, MO 63130, United […]
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“Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury” (2021) Nature Communications Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury (2021) Nature Communications, 12 (1), art. no. 781, . Brommer, B.a , He, M.a , Zhang, Z.a , Yang, Z.a , Page, J.C.a , Su, J.a , Zhang, Y.a , […]
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"A 2020 view of tension-based cortical morphogenesis" (2021) Proceedings of the National Academy of Sciences of the United States of America A 2020 view of tension-based cortical morphogenesis(2021) Proceedings of the National Academy of Sciences of the United States of America, 117 (52), pp. 32868-32879. van Essen, D.C. Department of Neuroscience, Washington University School of Medicine, Saint Louis, MO 63110, […]
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“‘It’s way more than just writing a prescription’: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder” (2021) Addiction Science and Clinical Practice “It’s way more than just writing a prescription”: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use […]
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“Exercise routine change is associated with prenatal depression scores during the COVID-19 pandemic among pregnant women across the United States” (2021) PLoS ONE Exercise routine change is associated with prenatal depression scores during the COVID-19 pandemic among pregnant women across the United States (2021) PLoS ONE, 15 (12 December), art. no. e0243188, . Gildner, T.E.a b , Laugier, E.J.a c , Thayer, Z.M.a c a Department of […]
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“A pilot investigation of emotional regulation difficulties and mindfulness-based strategies in manic and remitted bipolar I disorder and major depressive disorder” (2021) International Journal of Bipolar Disorders A pilot investigation of emotional regulation difficulties and mindfulness-based strategies in manic and remitted bipolar I disorder and major depressive disorder (2021) International Journal of Bipolar Disorders Musket, C.W.a , […]
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"Destigmatizing Naloxone: Associations of Perceived Availability on Opioid Use Patterns" (2021) Annals of Emergency Medicine Destigmatizing Naloxone: Associations of Perceived Availability on Opioid Use Patterns(2021) Annals of Emergency Medicine, 77 (1), pp. 134-135. Ellis, M.S., Kasper, Z.A., Cicero, T.J. Washington University in St. Louis, Department of Psychiatry, School of Medicine, St. Louis, MO, United States Document Type: LetterPublication Stage: FinalSource: Scopus "Prevalence, […]
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"Oral and maxillofacial surgeons’ assessment of the role of Pernkopf's atlas in surgical practice" (2021) Annals of Anatomy Oral and maxillofacial surgeons’ assessment of the role of Pernkopf’s atlas in surgical practice(2021) Annals of Anatomy, 234, art. no. 151614, . Yee, A.a , Li, J.b , Lilly, J.b , Hildebrandt, S.c , Seidelman, W.E.d , Brown, D.e , Kopar, P.e , Coert, J.H.f , Mackinnon, S.E.a , Israel, H.A.b a Division of […]
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“Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy” (2021) Gait and Posture Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy (2021) Gait and Posture, 84, pp. 38-44. Jeong, H.-J., Mueller, M.J., Zellers, J.A., Hastings, M.K. Program in Physical Therapy, […]
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“Cerebrospinal fluid Aβ42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability” (2021) Neurobiology of Aging Cerebrospinal fluid Aβ42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability (2021) Neurobiology of Aging, 98, pp. 116-123. Meeker, K.L.a b , Ances, B.M.b , Gordon, B.A.c , Rudolph, C.W.a , Luckett, P.b , Balota, D.A.d , Morris, J.C.b , Fagan, A.M.b , Benzinger, T.L.c , Waring, J.D.a […]
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“Fronto-cerebellar connectivity mediating cognitive processing speed” (2021) NeuroImage Fronto-cerebellar connectivity mediating cognitive processing speed (2021) NeuroImage, 226, art. no. 117556, . Wong, C.H.Y.a b c , Liu, J.d e f l , Lee, T.M.C.b c j k , Tao, J.d e l , Wong, A.W.K.g h , Chau, B.K.H.a i , Chen, L.d e l , Chan, C.C.H.a i a Applied Cognitive Neuroscience Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong b Laboratory of Neuropsychology and Human Neuroscience, Department of […]
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“Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants” (2020) Developmental Cognitive Neuroscience Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants (2020) Developmental Cognitive Neuroscience, 46, art. no. 100877, . Humphreys, K.L.a , Camacho, M.C.b , Roth, M.C.a , Estes, E.C.a a Vanderbilt University, Department of Psychology and Human Development, 230 Appleton Place, #552, Nashville, […]
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"Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the randomised, placebo-controlled, phase 3 trial" (2020) The Lancet Neurology Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the […]
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“Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study” (2021) Neurobiology of Aging Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study (2021) Neurobiology of Aging, 97, pp. 65-72. Walker, K.A.a , Chawla, S.b , Nogueras-Ortiz, C.b , Coresh, J.c , Sharrett, A.R.c , Wong, D.F.d , Jack, C.R., Jr.e , Spychalla, […]
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"Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage" (2021) Brain Research Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage(2021) Brain Research, 1750, art. no. 147169, . Athiraman, U.a , Liu, M.a , Jayaraman, K.b , Yuan, J.a , […]
Board of Trustees grants faculty appointments, promotions
At the Washington University in St. Louis Board of Trustees meeting Oct. 2, several faculty members were appointed or promoted with tenure or granted tenure, effective that day unless otherwise indicated… …Promotion with tenure Luis F.Z. Batista to associate professor of medicine and of developmental biology at the School of Medicine (tenure effective Jan. 1); Nico […]
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“N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury” (2021) Experimental Neurology N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury (2021) Experimental Neurology, 335, art. no. 113507, . Celorrio, M., Rhodes, J., Vadivelu, S., Davies, M., Friess, S.H. Division of Critical Care Medicine, Department of Pediatrics, Washington University in St. Louis School of Medicine, One […]
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“Relationships between accelerometry and general compensatory movements of the upper limb after stroke” (2020) Journal of NeuroEngineering and Rehabilitation Relationships between accelerometry and general compensatory movements of the upper limb after stroke (2020) Journal of NeuroEngineering and Rehabilitation, 17 (1), art. no. 138, . Barth, J.a , Klaesner, J.W.a d , Lang, C.E.a b c a Washington University School of Medicine, Program in Physical Therapy, St. Louis, […]
Racism’s hidden toll
MINNEAPOLIS — George Floyd came to this city with a broken body and wilted dreams, his many attempts at a better life out of his grasp. He was left with no college degree, no sports contract, no rap career, not even a steady job. At 43, what he had was an arrest record and a […]
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“Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells” (2020) Brain Research Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells (2020) Brain Research, 1749, art. no. 147139, . Matsuhisa, K.a b , Cai, L.a , Saito, A.a b , Sakaue, F.b , Kamikawa, Y.b , Fujiwara, S.b , Asada, R.c , Kudo, Y.d , Imaizumi, K.a a Department of Biochemistry, […]
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“Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders” (2021) Journal of Affective Disorders Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders (2021) Journal of Affective Disorders, 278, pp. 563-569. Scherrer, J.F.a , Salas, J.a , Grucza, R.a , Sullivan, M.D.b , Lustman, P.J.c d , […]
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“Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis” (2020) Journal of Ophthalmic Inflammation and Infection Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis (2020) Journal of Ophthalmic Inflammation and Infection, 10 (1), art. no. 24, . Sonne, S.J.a , Smith, B.T.b c a St. Louis University School of Medicine, St. […]
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“Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents” (2020) Journal of Controlled Release Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents (2020) Journal of Controlled Release, 328, pp. 276-285. Ye, D.a , Luan, J.a , Pang, H.b , Yang, Y.b , Nazeri, A.c , Rubin, J.B.d e , Chen, H.b f a Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, […]
William H. Danforth, chancellor emeritus, trustee emeritus of Washington University, dies at 94
Chancellor Emeritus William H. Danforth, MD, who served as chancellor for 24 of his more than 65 years of service to Washington University in St. Louis, died Wednesday, Sept. 16, 2020, at his home in Ladue, Mo. He was 94. Dr. Danforth, who was also an emeritus trustee, led the university into an era of […]
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“Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites” (2020) Molecular Pharmacology Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites (2020) Molecular Pharmacology, 98 (4), pp. 280-291. Germann, A.L., Reichert, D.E., Burbridge, A.B., Pierce, S.R., […]
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“Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction” (2020) Nature Communications Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction (2020) Nature Communications, 11 (1), art. no. 4358, . Ozawa, M.a b , Davis, P.a b c e , Ni, J.a , Maguire, J.a , Papouin, T.a d , Reijmers, L.a a Department of Neuroscience, School of Medicine, Tufts University, Boston, MA, United States b Graduate Program in […]
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“Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder” (2020) Translational Psychiatry Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder (2020) Translational Psychiatry, 10 (1), art. no. 298, . Lopes, F.L.a , Zhu, K.a , Purves, K.L.b , Song, C.a , Ahn, K.a , Hou, L.a , Akula, N.a , Kassem, L.a , Bergen, S.E.c , Landen, M.c d , Veras, A.B.e , Nardi, […]
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“Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice” (2020) Scientific Reports Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice (2020) Scientific Reports, 10 (1), art. no. 13630, . Akkaya, M.a , Bansal, A.b e , Sheehan, P.W.a f , Pena, […]
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“Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity” (2020) Nature Communications Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity (2020) Nature Communications, 11 (1), art. no. 3996, . Bariselli, S.a d , Miyazaki, N.L.a , Creed, M.C.b c , Kravitz, A.V.a c a National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States b Washington University Pain Center, St Louis, MO 63110, United States c Departments of Psychiatry, […]
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“Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease” (2020) The Journal of Experimental Medicine Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease (2020) The Journal of Experimental Medicine, 217 (11), . Barthélemy, N.R.a , Horie, K.a , Sato, C.a , Bateman, R.J.a b c a Department of Neurology, Washington University School of Medicine, St. Louis, MO b Hope Center for Neurological Disorders, […]
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"Gait asymmetry, and bilateral coordination of gait during a six-minute walk test in persons with multiple sclerosis" (2020) Scientific Reports Gait asymmetry, and bilateral coordination of gait during a six-minute walk test in persons with multiple sclerosis(2020) Scientific Reports, 10 (1), art. no. 12382, . Plotnik, M.a b c , Wagner, J.M.d , Adusumilli, G.e , Gottlieb, A.a , Naismith, R.T.e a Center of Advanced Technologies in Rehabilitation, […]
Cabassa receives $2.2M training grant renewal from NIMH
Leopoldo J. Cabassa, associate professor and co-director of the Center for Mental Health Services Research at the Brown School, has received a five-year $2.2 million training grant renewal from the National Institute of Mental Health of the National Institutes of Health (NIH). This training program previously led by Enola Proctor, builds upon the center’s 25-year history of successfully […]
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“A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation” (2020) Communications Biology A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation (2020) Communications Biology, 3 (1), art. no. 385, . Liu, Y.a , Xu, X.b , Gao, J.c , Naffaa, M.M.a , Liang, H.a , Shi, J.a , Wang, H.Z.c , Yang, N.-D.a , Hou, P.a , Zhao, W.a , White, K.M.F.a , Kong, W.a , Dou, A.a , Cui, A.a , Zhang, […]
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“Quantification of brain oxygen extraction and metabolism with (15O)-gas PET: A technical review in the era of PET-MRI” (2020) NeuroImage Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI (2020) NeuroImage, 220, art. no. 117136, . Fan, A.P.a b , An, H.c , Moradi, F.a , Rosenberg, J.a , Ishii, Y.a […]
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“A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine” (2020) Nature Communications A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine (2020) Nature Communications, 11 (1), art. no. 3368, . Guo, Y.a b c , Rist, P.M.a b c , Daghlas, I.a b , Giulianini, F.a , Gormley, P.e f g h , Anttila, V.f g i , Winsvold, B.S.j k l , Palta, P.m , Esko, T.f n o , Pers, T.H.f o p q , Farh, K.-H.f i r , Cuenca-Leon, E.e f g s , Muona, […]