The Systems Journal Club has spirited discussions of recent systems neuroscience papers, covering sensory, motor and cognitive issues.

Explore the archives below.

Systems Journal Club – 2024

March 8, 2024

Pingchuan Ma (Chen lab, WashU Neuroscience)

“Dopamine transients follow a striatal gradient of reward time horizons” Nature Neuroscience (2024)

March 15, 2024

Yuma Kanazawa (Padoa-Schioppa lab, WashU Neuroscience)

“Synaptic wiring motifs in posterior parietal cortex support decision-making” Nature (2024)

March 22, 2024

Fatih Sogukpinar, Julia Pai (Monosov lab, WashU Neuroscience)

“Expertise increases planning depth in human gameplay” Nature (2023)

March 29, 2024

Eleonora Bano (Kepecs lab, WashU Neuroscience)

“Bumblebees socially learn behaviour too complex to innovate alone” Nature (2024)

April 5, 2024

JeongJun Park (Snyder lab, WashU Neuroscience)

“Orthogonal representations for robust context-dependent task performance in brains and neural networks” Neuron (2022)

April 12, 2024

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Self-orienting in human and machine learning” Nature Human Behaviour (2023)

April 19, 2024

Gerardo Molina (Han lab, WashU Neuroscience)

“Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning” bioRxiv (2023)

April 26, 2024

Maryam Azadi (Franken lab, WashU Neuroscience)

“Visuo-frontal interactions during social learning in freely moving macaques” Nature (2024)

May 3, 2024

Kaining Zhang (Tavoni lab, WashU Neuroscience)

“Inhibitory Plasticity Enhances Sequence Storage Capacity and Retrieval Robustness” bioRxiv (2024)

May 24, 2024

Eleanora Bano, Steven Ryu (Kepecs lab, WashU Neuroscience)

“A latent pool of neurons silenced by sensory-evoked inhibition can be recruited to enhance perception” Neuron (2024)

May, 31, 2024

Miguel Barretto-Garcia (Padoa-Schioppa lab, WashU Neuroscience)

“Preferences reveal dissociable encoding across prefrontal-limbic circuits” Neuron (2024)

Systems Journal Club – 2023
January 6, 2023

Martha Bagnall (WashU Neuroscience)

“Movement is governed by rotational neural dynamics in spinal motor networks” Nature (2022)

Mini-series “Reinforcement Learning”

Questions to ponder over and discuss:

  1. Are the two models (paper 1 vs 2) actually contentious? What kind of framework or experiment is required to resolve the contention?
  2. Which of the two types of models pushes our understanding forward for how learning operates? Where does each approach fail?
January 13, 2023

Apoorva Arora (Kepecs lab, WashU Neuroscience)

“A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning” Nature Neuroscience (2022)

This paper shows that the DA transient moves backward from the time of reward to the time of cue over successive trials. This result had been missing so far in the TD-RL framework for learning via DA.

January 20, 2023

Apoorva Arora (Kepecs lab, WashU Neuroscience)

“Mesolimbic dopamine release conveys causal associations” Science 2022

This paper builds on a different model (ANCCR) to explain the association between cue and reward through DA signals. They claim that their model explains DA signals that are not explained by the TDRL framework.

February 3, 2023

Fatih Sogukpinar, Yang-Yang Feng (Monosov lab, WashU Neuroscience)

“Mesolimbic dopamine adapts the rate of learning from action” Nature (2023)

February 17, 2023

Gerardo Molina (Han lab, WashU Neuroscience)

“Task-selective place cells show behaviorally driven dynamics during learning and stability during memory recall” Cell Reports (2022)

February 24, 2023

Adithya Rajagopalan (Johns Hopkins University)

“Reward expectations direct learning and drive operant matching in Drosophila”

March 3, 2023

NOTE start time: 1:30p

Part I of a 2-part series on neural correlates of timing, temporal expectations, and time perception

Steven Ryu (Kepecs lab, WashU Neuroscience)

“Distinct Sources of Deterministic and Stochastic Components of Action Timing Decisions in Rodent Frontal Cortex” Neuron (2017)

March 10, 2023

Part II of a 2-part series on neural correlates of timing, temporal expectations, and time perception

Junxiao Hou (Kepecs lab, WashU Neuroscience)

“Midbrain dopamine neurons control judgment of time” Science (2016)

April 7, 2023

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Propofol disrupts alpha dynamics in functionally distinct thalamocortical networks during loss of consciousness” PNAS (2023)

April 14, 2023

James McGregor (Hengen lab, WashU Biology)

“Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer’s disease model mice” Nature Neuroscience (2023)

April 21, 2023

NOTE location East McDonnell 3rd fl conference room

Tom Franken (WashU Neuroscience)

“Suppressing feedback signals to visual cortex abolishes attentional modulation” Science (2023)

April 28, 2023

NOTE location East McDonnell 3rd fl conference room

Steven Errington (Monosov lab, WashU Neuroscience)

“A Basal Forebrain-Cingulate Circuit in Macaques Decides It Is Time to Act” Neuron (2020)

May 5, 2023

Eleanor Bano (Kepecs lab, WashU Neuroscience)

“The role of state uncertainty in the dynamics of dopamine” Current Biology (2023)

CANCELLED – May 12, 2023

Snyder lab (WashU Neuroscience)

May 26, 2023

Jung Uk Kang (Snyder lab, WashU Neuroscience)

“Causal Evidence for the Processing of Bodily Self in the Anterior Precuneus” Neuron (2023)

June 2, 2023

NOTE location: McDonnell 455

Zahra Dhanerawala (Han lab, WashU Neuroscience)

“Learnable latent embeddings for joint behavioural and neural analysis” Nature (2023)

June 9, 2023

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“A motor association area in the depths of the central sulcus” Nature Neuroscience (2023)

CANCELLED – June 16, 2023

Monosov lab (WashU Neuroscience)

June 30, 2023

NOTE location: McDonnell 455

Christian Monroy Hernandez (Chen lab, WashU Neuroscience)

“Esr1+ hypothalamic-habenula neurons shape aversive states” Nature Neuroscience (2023)

September 15, 2023

Miguel Antonio Garcia (Padoa-Schioppa lab, WashU Neuroscience)

“Orbitofrontal cortex control of striatum leads economic decision-making” Nature Neuroscience (2023)

September 29, 2023

Fatih Sogukpinar, Julia Pai (Monosov lab, WashU Neuroscience)

“Reliable population code for subjective economic value from heterogeneous neuronal signals in primate orbitofrontal cortex” Neuron (2023)

October 6, 2023

Steven Ryu (Kepecs lab, WashU Neuroscience)

“Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans” Nature Neuroscience (2023)

October 13, 2023

No meeting: We encourage you to attend the Annual Neuroscience Retreat!

October 20, 2023

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Hippocampal neurons code individual episodic memories in humans” Nature Human Behavior (2023)

October 27, 2023

JeongJun Park (Snyder lab, WashU Neuroscience)

“Geometry of sequence working memory in macaque prefrontal cortex” Science (2022)

CANCELLED – November 3, 2023

Monosov lab (WashU Neuroscience)

November 10, 2023

No meeting: See you at SfN!

CANCELLED – November 17, 2023

Please consider attending the Neuroscience Special Seminar: Akiya Watakabe (RIKEN Center for Brain Science)“Columns and Clouds: Two faces of marmoset prefrontal projections”

Camillo Padoa-Schioppa (WashU Neuroscience)

“SfN debrief”

November 24, 2023

No meeting: Thanksgiving

December 1, 2023

Apoorva Arora (Kepecs lab, WashU Neuroscience)

“Dual credit assignment processes underlie dopamine signals in a complex spatial environment” Neuron (2023)

CANCELLED – December 8, 2023

Tavoni lab (WashU Neuroscience)

December 15, 2023

Fatemeh Didehvar (Franken lab, WashU Neuroscience)

“A dynamic sequence of visual processing initiated by gaze shifts” Nature Neuroscience (2023)

Systems Journal Club – Fall 2022
September 23, 2022

Burke Rosen (University of California, San Diego)

“Exponential distance rules for human structural & functional cortical connectivity”

September 30, 2022

Lizzie Tilden (Chen lab, WashU Neuroscience)

“Precisely timed theta oscillations are selectively required during the encoding phase of memory” Nature Neuroscience (2021)

October 21, 2022

Julia Pai (Monosov lab, WashU Neuroscience)

“Neural representational geometry correlates with behavioral differences between monkeys” bioRxiv (2022)

October 28, 2022

Kaining Zhang (Tavoni lab, WashU Neuroscience)

“Optimizing the human learnability of abstract network representations” PNAS (2022)

Additional reading:

November 4, 2022

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Reduced neural feedback signaling despite robust neuron and gamma auditory responses during human sleep” Nature Neuroscience (2022)

November 18, 2022

Special SfN debrief session

CANCELLED – December 2, 2022

Mini-series: Reinforcement Learning

Kepecs lab (WashU Neuroscience)

December 9, 2022

JeongJun Park (Snyder lab, WashU Neuroscience)

“Coupled ripple oscillations between the medial temporal lobe and neocortex retrieve human memory” Science (2019)

VIRTUAL – December 16, 2022

Yi Qin (Netherlands Institute for Neuroscience)

“Thalamic regulation of ocular dominance plasticity in adult visual cortex”

Systems Journal Club – Spring 2022

January 7, 2022

Jung Uk Kang (Snyder lab, WashU Neuroscience)

“Cortical control of virtual self-motion using task-specific subspaces” Journal of Neuroscience (2021)

January 21, 2022

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“A speech planning network for interactive language use” Nature (2022)

February 4, 2022

Keenan Ronayne (Hengen lab, WashU Biology)

“Population-specific neuromodulation prolongs therapeutic benefits of deep brain stimulation”  Science (2021)

February 11, 2022 

Keran Yang, Apoorva Arora (Kepecs lab, WashU Neuroscience)

“Coordination of escape and spatial navigation circuits orchestrates versatile flight from threats”  Neuron (2021)

 February 18, 2022

CANCELLED – Padoa-Schioppa lab (WashU Neuroscience)

February 25, 2022

Kaining Zhang (Monosov lab, WashU Neuroscience)

“Meta-learning synaptic plasticity and memory addressing for continual familiarity detection”  Neuron (2022)

March 11, 2022

Ben Acland (Snyder lab, WashU Neuroscience)

“A mechanism for inter-areal coherence through communication based on connectivity and oscillatory power”  Neuron (2021)

March 18, 2022

Han lab (WashU Neuroscience)

March 25, 2022

Hengen lab (WashU Biology)

April 1, 2022

Amy Christensen (Kepecs lab, WashU Neuroscience)

“A Model That Accounts for Activity in Primate Frontal Cortex during a Delayed Matching-to-Sample Task” Journal of Neuroscience (1998)

“Orthogonal representations for robust context dependent task performance in brains and neural networks” Neuron (2022)

April 8, 2022

Miguel Barretto Garcia (University of Zurich)

“The neurocomputational links between perceptual and economic choice”

Talk abstract

April 15, 2022

CANCELLED – Monosov lab (WashU Neuroscience)

April 22, 2022

Jung Uk Kang (Snyder lab, WashU Neuroscience)

“Shared mechanisms underlie the control of working memory and attention” (Nature 2021)

April 29, 2022

Pingchuan Ma (Chen lab, WashU Neuroscience)

“Rapid eye movement sleep is initiated by basolateral amygdala dopamine signaling in mice”  Science (2022)

May 6, 2022

Gaia Tavoni (WashU Neuroscience)

“Compression as a path to simplification: Models of collective neural activity” arXiv:2112.14334v1 (2021)

May 13, 2022

CANCELLED – Kepecs lab (WashU Neuroscience)

May 13, 2022

CCSN Mini-Retreat
9:30a
Umrath Lounge, Danforth Campus

Gaia Tavoni (WashU Neuroscience)

“Optimal strategies for information encoding and retrieval”

May 20, 2022

Larry Snyder (WashU Neuroscience)

“Reproducible brain-wide association studies require thousands of individuals”  Nature 2022

May 27, 2022

Julia Pai (Monosov lab, WashU Neuroscience), Luke Gong and Giacomo Vedovati (Ching lab, WashU Electrical and Systems Engineering)

“Multiplexed action-outcome representation by striatal striosome-matrix compartments detected with a mouse cost-benefit foraging task”  Nature Communications (2022)

June 3, 2022

Juliusz Cydzik (Snyder lab, WashU Neuroscience)

“Remote, brain region–specific control of choice behavior with ultrasonic waves”  Science Advances (2020)

June 10, 2022

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Single-neuron firing cascades underlie global spontaneous brain events” Proc Natl Acad Sci U S A (2021)

Systems Journal Club – Fall 2021

September 3, 2021

Weikang Shi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Hippocampal neurons construct a map of an abstract value space” Cell 2021

September 10, 2021

Apoorva Arora (Kepecs lab, WashU Dept. of Neuroscience)

“Mice in a labyrinth show rapid learning, sudden insight, and efficient exploration”  eLife 2021

September 17, 2021

Yang-Yang Feng (Monosov lab, WashU Dept. of Neuroscience)

“Wave-like dopamine dynamics as a mechanism for spatiotemporal credit assignment”  Cell 2021

September 24, 2021

Charles Holmes (Snyder lab, WashU Dept. of Neuroscience)

“Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network” eLife 2020

Wednesday, September 29, 2021* – *NOTE day

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Neural oscillations track natural but not artificial fast speech: Novel insights from speech-brain coupling using MEG”  Neuroimage 2021

October 8, 2021

Aelita Xiaoyue Zhu (Kepecs lab, WashU Neuroscience)

“Whole-Brain Functional Ultrasound Imaging Reveals Brain Modules for Visuomotor Integration”  Neuron 2018

October 15, 2021

Alessandro Livi (Padoa-Schioppa lab, WashU Neuroscience)

“Dopamine release in the nucleus accumbens core signals perceived saliency”  Current Biology (2021)

October 22, 2021

JeongJun Park (Monosov lab, WashU Neuroscience)

“Spike Timing in the Attention Network Predicts Behavioral Outcome Prior to Target Selection”  Neuron (2020)

October 29, 2021 – NOTE 2:00p start time

Jan Zimmermann (University of Minnesota)

“Timescales of behavior and neural processing”

November 5, 2021

Pingchuan Ma (Chen lab, WashU Neuroscience)

“Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling”  Nature (2021)

Wednesday, November 17, 2021 – NOTE day

Muneshwar Mehra (Han lab, WashU Neuroscience)

“The orbitofrontal cortex maps future navigational goals”  Nature (2021)

December 3, 2021

Steven Ryu (Kepecs lab, WashU Neuroscience)

“Reverse-translational identification of a cerebellar satiation network”  Nature (2021)

December 10, 2021

Jiaxin Cindy Tu (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Geometry of abstract learned knowledge in the hippocampus”  Nature (2021)

CANCELLED – December 17, 2021

Monosov lab (WashU Neuroscience)

Systems Journal Club – Spring/Summer 2021

January 8, 2021

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

“Midbrain activity shapes high-level visual properties in the primate temporal cortex”  Neuron (2020)

January 15, 2021

Keran Yang, Steven Ryu (Kepecs lab, WashU Dept. of Neuroscience)

“Anterior cingulate inputs to nucleus accumbens control the social transfer of pain and analgesia”  Science (2021)

January 22, 2021

Weikang Shi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Activation and disruption of a neuralmechanism for novel choice in monkeys”  Nature (2021)

January 29, 2021

Victoria Zhang, Katie Mueller (Ponce lab, WashU Dept. of Neuroscience)

“The Emergence of Semantic Meaning in the Ventral Temporal Pathway”  Journal of Cognitive Neuroscience (2014)

February 5, 2021

Shashank Anand ( Moran lab, WashU Biomedical Engineering)

“Long-range phase synchronization of high-frequency oscillations in human cortex” Nature Communications (2020) 

February 12, 2021

Guest Speaker (Host: Ilya Monosov (WashU Dept .of Neuroscience))

February 19, 2021

Ben Acland (Snyder lab, WashU Dept. of Neuroscience)

“High-amplitude cofluctuations in cortical activity drive functional connectivity”  PNAS (2020)

February 26, 2021 – CCSN Annual Retreat, no journal club

March 5, 2021

Manning Zhang (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Sequential and efficient neural-population coding of complex task information”  bioRxiv (2021)

March 12, 2021

Pingchuan Ma (Chen lab, WashU Dept. of Neuroscience)

“A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion”  Cell (2020)

March 19, 2021

Charles Holmes (Snyder lab, WashU Dept. of Neuroscience)

“Lateralization of Executive Function: Working Memory Advantage for Same Hemifield Stimuli in the Monkey”  Frontiers in Neuroscience (2017)

March 26, 2021 

Apoorva Arora (Kepecs lab, WashU Dept. of Neuroscience)

“Reset of hippocampal–prefrontal circuitry facilitates learning”  Nature (2021)

April 2, 2021

Gaia Tavoni (WashU Dept. of Neuroscience)

“Perspective: Sloppiness and emergent theories in physics, biology, and beyond” Journal of Chemical Physics (2015)

April 9, 2021

Sarah Starosta, Quentin Chevy (Kepecs lab, WashU Dept. of Neuroscience

“An amygdala circuit that suppresses social engagement”  Nature (2021)

April 16, 2021

Alessandro Livi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Primate Amygdala Neurons Simulate Decision Processes of Social Partners”  Cell (2019)

April 23, 2021

Carlos Ponce, Binxu Wang (WashU Dept. of Neuroscience)

“Feedforward and feedback interactions between visual cortical areas use different population activity patterns”  bioRxiv (2021)

April 30, 2021  NOTE 12:30p start

Kaining Zhang (Monosov lab, WashU Dept. of Neuroscience)

“Rare rewards amplify dopamine responses”  Nature Neuroscience (2021)

May 7, 2021

Gerardo Molina, Eleanora Bano (Han lab, WashU Dept. of Neuroscience)

“Targeted Activation of Hippocampal Place Cells Drives Memory-Guided Spatial Behavior”  Cell (2020)

May 14, 2021

Yifan Xu (Hengen lab, WashU Biology)

“Mouse prefrontal cortex represents learned rules for categorization”  Nature (2021)

May 21, 2021

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Functional Connectome Prediction of Anxiety Related to the COVID-19 Pandemic”  American Journal of Psychiatry (2021)

May 28, 2021

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

“Evidence for an attentional priority map ininferotemporal cortex”  PNAS (2019)

June 4, 2021

Suelynn Ren (Kepecs lab, WashU Dept. of Neuroscience)

“Stochastic synaptic plasticity underlying compulsion in a model of addiction” Nature (2018)

June 11, 2021

Jiaxin (Cindy) Tu (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“First-Pass Processing of Value Cues in the Ventral Visual Pathway”  Current Biology (2018)

June 18, 2021

Olivia Bockler, Katie Mueller (Ponce lab, WashU Dept. of Neuroscience)

“Audiovisual integration in macaque face patch neurons” Current Biology (2021)

CANCELLED – June 25, 2021

Monosov lab, WashU Dept. of Neuroscience

Systems Journal Club – Fall 2020

September 4, 2020

Alessandro Livi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Stable representations of decision variables for flexible behavior”     Neuron (2019)

September 11, 2020

Olivia Bockler (Ponce lab, WashU Dept. of Neuroscience)

“Multisensory Neurons in the Primate Amygdala”   Journal of Neuroscience (2019)

September 18, 2020

Ben Acland (Snyder lab, WashU Dept. of Neuroscience)

“Deep posteromedial cortical rhythm in dissociation”  Nature (2020)

September 25, 2020

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Modulating dream experience: Noninvasive brain stimulation over the sensorimotor cortex reduces dream movement”   Scientific Reports (2020)

October 9, 2020

Apoorva Arora, Amelia Christiansen (Kepecs lab, WashU Dept. of Neuroscience)

“Deep posteromedial cortical rhythm in dissociation”  Nature (2020)

October 16, 2020

Eleanora Bano (Han lab, WashU Dept. of Neuroscience)

“Alternating sequences of future and past behavior encoded within hippocampal theta oscillations”  Science (2020)

October 23, 2020

Keith Hengen (WashU Biology)

“Using temperature to analyse temporal dynamics in the songbird motor pathway”  Nature (2008)

October 30, 2020

Jiaxin Cindy Tu (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“The Effect of Counterfactual Information on Outcome Value Coding in Medial Prefrontal and Cingulate Cortex: From an Absolute to a Relative Neural Code”  Journal of Neuroscience (2020)

November 6, 2020

Charles Holmes (Snyder lab, WashU Dept. of Neuroscience)

“Frontal eye field neurons selectively signal the reward value of prior actions”  Progress in Neurobiology (2020)

November 13, 2020

Yang-Yang Feng (Monosov lab, WashU Dept. of Neuroscience)

“Serotonin neurons modulate learning rate through uncertainty” bioRxiv (2020)

November 20, 2020

Tzvia Pinkhasov (Kepecs lab, WashU Dept. of Neuroscience)

“Dynamic dopaminergic activity controls the timing of self-timed movement” bioRxiv (2020)

December 4, 2020

Manning Zhang (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Primate anterior insular cortex represents economic decision variables postulated by Prospect theory”  bioRxiv (2020)

December 11, 2020

Binxu Wang (Ponce lab, WashU Dept. of Neuroscience)

“Retino-Cortical Mapping Ratio Predicts Columnar and Salt-and-Pepper Organization in Mammalian Visual Cortex” Cell (2020)

December 18, 2020

Eleonora Bano (Han lab, WashU Dept. of Neuroscience)

“A neural correlate of sensory consciousness in a corvid bird”  Science (2020)

Systems Journal Club – Summer 2020

June 19, 2020

First Year Students Qualifying Exam Preparation

June 26, 2020

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Machine translation of cortical activity to text with an encoder–decoder framework” Nature Neuroscience (2020)

July 3, 2020

Open social: the informal, non-binding topic is, “What are you reading?” Science, social justice, fiction, or anything else.

July 10, 2020

Carlos Ponce (WashU Dept. of Neuroscience)

“Women’s visibility in academic seminars: Women ask fewer questions than men”  PLOS ONE (2018)

July 17, 2020

Apoorva Arora (Kepecs lab, WashU Dept. of Neuroscience)

“Constant Sub-second Cycling between Representations of Possible Futures in the Hippocampus” Cell (2020)

CANCELLED – July 24, 2020

Monosov lab, WashU Dept. of Neuroscience

July 31, 2020

Eleonora Bano (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Membrane potential dynamics underlying context-dependent sensory responses in the hippocampus”Nature Neuroscience (2020)

August 7, 2020

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

“Perisaccadic Receptive Field Expansion in the Lateral Intraparietal Area” Neuron (2020)

August 14, 2020

Julia Pai (Monosov lab, WashU Dept. of Neuroscience)

“Dopamine axons to dorsal striatum encode contralateral stimuli and actions” bioRxiv (2020)

August 21, 2020

Xubo Leng (Chen lab, WashU Dept. of Neuroscience)

“Cortical reactivations of recent sensory experiences predict bidirectional network changes during learning”  Nature Neuroscience (2020)

August 28, 2020

Steven Ryu (Kepecs lab, WashU Dept. of Neuroscience)

“Transient and Persistent Representations of Odor Value in Prefrontal Cortex”  Neuron (2020)

Systems Journal Club – Spring 2020

January 10, 2020

Weikang Shi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Dopaminergic and Prefrontal Basis of Learning from Sensory Confidence and Reward Value” Neuron 2019

January 17, 2020

Binxu Wang (Ponce lab, WashU Dept. of Neuroscience)

“High precision coding in visual cortex” bioRxiv 2019

Related article:

January 24, 2020

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

“A simple linear readout of MT supports motion direction-discrimination performance”  J. Neurophysiology 2019

January 31 – No journal club, Neuroscience Program interviews

February 7, 2020

Jamie Moffa (Monosov lab, WashU Dept. of Neuroscience)

“Encoding of danger by parabrachial CGRP neurons”  Nature 2018

February 14 – No journal club, Neuroscience Program interviews

February 21, 2020 – CCSN Retreat (9-5:00p Danforth campus)

February 28, 2020

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Monovision and the Misperception of Motion”  Current Biology 2019

March 6, 2020

Manning Zhang (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Value and choice as separable, stable representations in orbitofrontal cortex” bioRxiv 2019

March 13, 2020– join in email discussion!

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

  • “Reaching decisions during ongoing movements”Journal of Neurophysiology 2020
  • Please feel free to share your thoughts or feedback through the jclub mailing list: We often make decisions while moving (i.e. “decide-while-acting”). Drummers, for instance, decide when and where to move their arms during movement. In lab settings, however, researchers often use standard delay tasks (i.e. “decide-then-act”), and most action selection models are based on this “decide-then-act” paradigm. Michalski and colleagues asked human subjects to track moving targets, and the authors demonstrate interesting differences from the classical “decide-then-act” model. Biomechanical cost, which is computed by muscle torque to make switching movements to a different target, does not correspond to subjects’ probability of switching. They use this data to hypothesize neural circuits for controlling ongoing movements and those for action selection are different, and that biomechanical costs may be computed in the cerebellum.

CANCELLED – March 20, 2020

Monosov lab, WashU Dept. of Neuroscience

March 27, 2020 

Weikang Shi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Closed-Loop Theta Stimulation in the Orbitofrontal Cortex Prevents Reward-Based Learning” Neuron 2020

April 3, 2020

Torben Ott (Kepecs lab, WashU Dept. of Neuroscience)

“Frontal cortex neuron types categorically encode single decision variables”  Nature 2019

April 10, 2020

James Johnson (Ponce lab, WashU Dept. of Neuroscience)

“High-dimensional geometry of population responses in visual cortex” Nature 2019

Additional reading: “The intrinsic attractor manifold and population dynamics of a canonical cognitive circuit across waking and sleep.” Nature Neuroscience 2019

April 17, 2020 

Alessandro Livi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Area-Specificity and Plasticity of History-Dependent Value Coding During Learning”  Cell (2020)

April 24, 2020 

Larry Snyder, WashU Dept. of Neuroscience

“The Correlation of Neuronal Signals with Behavior at Different Levels of Visual Cortex and Their Relative Reliability for Behavioral Decisions”  Journal of Neuroscience (2020)

May 1, 2020 1:00 PM – NOTE time

Yang-Yang Feng (Monosov lab, WashU Dept. of Neuroscience)

“A distributional code for value in dopaminebased reinforcement learning” Nature (2020)

May 8, 2020

Kusch Qin (Chen lab, WashU Dept. of Neuroscience)

“Facial expressions of emotion states and their neuronal correlates in mice”  Science (2020)

May 15, 2020

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Using Coherence-based spectrospatial filters for stimulus features prediction from electrocorticographic recordings”  Scientific Reports (2020)

May 22, 2020

Manning Zhang (Padoa-Schioppa Lab, WashU Dept. of Neuroscience)

“Inference-Based Decisions in a Hidden State Foraging Task: Differential Contributions of Prefrontal Cortical Areas”  Neuron (2020)

May 29, 2020

Charles Holmes (Snyder lab, WashU Dept. of Neuroscience)

“Neurons in FEF Keep Track of Items That Have Been Previously Fixated in Free Viewing Visual Search”  The Journal of Neuroscience (2019)

June 5, 2020 – moved to 12:30p start time

Ethan Bromberg-Martin (Monosov lab, WashU Dept. of Neuroscience

“Opposing Contributions of GABAergic and Glutamatergic Ventral Pallidal Neurons to Motivational Behaviors”  Neuron 2020

Systems Journal Club Schedule – Fall 2019

August 23, 2019

Weikang Shi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Hierarchical reasoning by neural circuits in the frontal cortex”  Science (2019)

September 6, 2019

Chuck Holmes (Snyder lab, WashU Dept. of Neuroscience)

“Working memory capacity is enhanced by distributed prefrontal activation and invariant temporal dynamics” PNAS (2019)

September 13, 2019

Kaining Zhang (Monosov Lab, WashU Dept. of Neuroscience)

“Human Replay Spontaneously Reorganizes Experience” Cell (2019)

September 20, 2019

Shashank Anand (Moran lab, WashU Biomedical Engineering)

“Control of Spreading Depression with Electrical Fields” Scientific Reports (2018)

October 4, 2019

Olivia Bockler (Ponce lab, WashU Dept. of Neuroscience)

“A neural network model of flexible grasp movement generation” bioRxiv (2019)

October 11, 2019

Eric Mooshagian (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Posterior parietal cortex plays a causal role in perceptual and categorical decisions” Science (2019)

October 25, 2019

Cindy Tu (Snyder lab, WashU Dept. of Neuroscience)

“Autocorrelation structure at rest predicts value correlates of single neurons during reward-guided choice” eLife (2016)

November 1, 2019

Takaya Ogasawara (Monosov lab, WashU Dept. of Neuroscience)

“The cost of obtaining rewards enhances the reward prediction error signal of midbrain dopamine neurons”  Nature Communications (2019)

November 8, 2019

Gerardo Molina (Han lab, WashU Dept. of Neuroscience)

“The hippocampal engram maps experience but not place” Science (2018)

November 15, 2019

Yao Chen (WashU Dept. of Neuroscience)

“State-specific gating of salient cues by midbrain dopaminergic input to basal amygdala”  Nature Neuroscience (2019)

November 22, 2019

Alessandro Livi (Padoa-Schioppa lab, WashU Dept. of Neuroscience)

“Context-dependent decision making in a premotor circuit”  bioRxiv (2019)

December 6, 2019

Jung Uk Kang (Snyder lab, WashU Dept. of Neuroscience)

“Holding the arm still through integration of cortical commands” bioRxiv (2019)

December 13, 2019

Sid Sivakumar (Moran lab, WashU Biomedical Engineering)

“Decreased electrocortical temporal complexity distinguishes sleep from wakefulness” Scientific Reports (2019)

CANCELED – December 20, 2019

This Friday’s journal club has been pushed to January. Happy Holidays!
Ponce lab

WashU Dept. of Neuroscience

Systems Journal Club Schedule – Spring 2019

February 1, 2019

Alessandro Livi
Padoa Schioppa Lab, WashU Dept. of Neuroscience

“Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour” Nature (2019)

February 15, 2019

Jung-Uk Kang
Snyder Lab, WashU Dept. of Neuroscience

“Perturbation of macaque supplementary motor area produces context-independent changes in the probability of movement initiation” Journal of Neuroscience (2019)

February 22, 2019

Kaining Zhang
Monosov Lab, WashU Dept. of Neuroscience

“Cortical microcircuitry of performance monitoring” Nature Neuroscience (2019)

March 1, 2019

Carlos Ponce
WashU Dept. of Neuroscience

“Inception in visual cortex: in vivo-silico loops reveal most exciting images”  bioRxiv (2018)

March 8, 2019

Shashank Anand
Moran Lab, WashU Biomedical Engineering

“Direct Electrophysiological Correlates of Body Ownership in Human Cerebral Cortex”  Cerebral Cortex (2019)

March 15, 2019

Ahmad Jezzini
Padoa-Schioppa Lab, WashU Dept. of Neuroscience

“Interaction of taste and place coding in the hippocampus”  Journal of Neuroscience (2019)

CANCELLED March 22, 2019

Snyder Lab
WashU Dept. of Neuroscience

March 29, 2019

Ethan Bromberg-Martin
Monosov Lab, WashU Dept. of Neuroscience

“Dopamine Neurons Reflect the Uncertainty in Fear Generalization” Neuron (2018)

April 5, 2019

Suyash Harlalka
Han Lab, WashU Dept. of Neuroscience

“Reverse Replay of Hippocampal Place Cells Is Uniquely Modulated by Changing Reward”  Neuron (2016)

April 12, 2019

Pingchuan Ma
Chen Lab, WashU Dept. of Neuroscience

“Neuromodulatory control of localized dendritic spiking in critical period cortex” Nature (2019)

April 19, 2019

Manning Zhang
Padoa-Schioppa Lab, WashU Dept. of Neuroscience

“A gut-to-brain signal of fluid osmolarity controls thirst satiation”  Nature 2019

April 26, 2019

Chuck Holmes
Snyder Lab, WashU Dept. of Neuroscience

“Color-Change Detection Activity in the Primate Superior Colliculus” eNeuro 2017

May 10, 2019

Kaining Zhang
Monosov Lab, WashU Dept. of Neuroscience

“Positive reward prediction errors during decisionmaking strengthen memory encoding” Nature Human Behaviour 2019

CANCELLED May 17, 2019

Ponce Lab
WashU Dept. of Neuroscience

May 24, 2019

Tyler Schlichenmeyer
Moran Lab, WashU Biomedical Engineering

“Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior” Neuron 2019

May 31, 2019

Weikang Shi
Padoa-Schioppa Lab, WashU Dept. of Neuroscience

“Rotational Dynamics Reduce Interference Between Sensory and Memory Representations” bioRxiv 2019

June 7, 2019

Jung Uk Kang
Snyder Lab, WashU Dept. of Neuroscience

“Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response” Neuron 2018

CANCELLED June 14, 2019

Monosov Lab
WashU Dept. of Neuroscience

Systems Journal Club Schedule – Fall 2018

November 9, 2018

Society for Neuroscience (SfN) debrief

CANCELLED November 16, 2018

Monosov Lab
WashU Dept. of Neuroscience

CANCELLED November 30, 2018

Snyder Lab
WashU Dept. of Neuroscience

December 7, 2018

Alessandro Livi
Padoa-Schioppa Lab, WashU Dept. of Neuroscience

“Orbital frontal cortex updates state-induced value change for decision-making” Baltz, et al. Elife 2018

December 14, 2018

Carlos Ponce
WashU Dept. of Neuroscience

“A probabilistic population code based on neural samples” Shivkumar, et al. NIPS 2018

background articles:

December 21, 2018

Tyler Schichenmeyer
Moran Lab, WashU Biomedical Engineering

“Direct Electrical Stimulation of Lateral Orbitofrontal Cortex Acutely Improves Mood in Individuals with Symptoms of Depression” Rao, et al. Current Biology 2018