Board grants faculty appointments, promotions, tenure

At the Washington University in St. Louis Board of Trustees meeting March 5, numerous faculty members were appointed or promoted with tenure or granted tenure, effective July 1 unless otherwise indicated. Promotion with tenure Ruopeng An to associate professor at the Brown School; Arpita Bose to associate professor of biology in Arts & Sciences; Hong […]

WashU weekly Neuroscience publications

"TDP-43 and PINK1 mediate CHCHD10 S59L mutation–induced defects in Drosophila and in vitro" (2021) Nature Communications TDP-43 and PINK1 mediate CHCHD10 S59L mutation–induced defects in Drosophila and in vitro(2021) Nature Communications, 12 (1), art. no. 1924, .  Baek, M.a , Choe, Y.-J.a , Bannwarth, S.b , Kim, J.H.a , Maitra, S.a , Dorn, G.W., IIc , Taylor, J.P.d , Paquis-Flucklinger, V.b , Kim, N.C.a a Department of Pharmacy Practice and Pharmaceutical […]

WashU weekly Neuroscience publications

“Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders” (2021) Journal of Neurodevelopmental Disorders Shared developmental gait disruptions across two mouse models of neurodevelopmental disorders (2021) Journal of Neurodevelopmental Disorders, 13 (1), art. no. 10, .  Rahn, R.M.a b c , Weichselbaum, C.T.a b d , Gutmann, D.H.d e , Dougherty, J.D.a b d , Maloney, S.E.b d a Department of Genetics, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO […]

Brain Tumor Center established at Siteman Cancer Center

Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital have established the Brain Tumor Center, a multidisciplinary practice of physicians and scientists whose mission is to provide leading-edge, patient-centric care for brain tumor patients while also developing transformative basic, translational and clinical research to develop new therapies and improve patient outcomes. Neurosurgeon and scientist Albert H. Kim, […]

WashU weekly Neuroscience publications

“The transcriptional landscape of Shh medulloblastoma” (2021) Nature Communications The transcriptional landscape of Shh medulloblastoma (2021) Nature Communications, 12 (1), art. no. 1749, .  Skowron, P.a b c , Farooq, H.a b c , Cavalli, F.M.G.a c , Morrissy, A.S.d e f , Ly, M.a b c , Hendrikse, L.D.a c g , Wang, E.Y.a c g , Djambazian, H.h i , Zhu, H.g j , Mungall, K.L.k , Trinh, Q.M.j , Zheng, T.l , Dai, S.m , Stucklin, A.S.G.a c , Vladoiu, M.C.a b c , Fong, V.a c , Holgado, B.L.a c , Nor, C.a c , Wu, […]

WashU weekly Neuroscience publications

“Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis” (2021) Acta Neuropathologica Communications Gut microbial dysbiosis after traumatic brain injury modulates the immune response and impairs neurogenesis (2021) Acta Neuropathologica Communications, 9 (1), art. no. 40, .  Celorrio, M.a , Abellanas, M.A.a c d , Rhodes, J.a , Goodwin, V.a , Moritz, J.a , Vadivelu, S.a , Wang, L.b , Rodgers, R.b , Xiao, S.a , Anabayan, […]

FUSIN promising in therapeutic agent delivery to brain tumor

Brainstem glioma is often diagnosed in children and young adults and has a low survival rate. A multidisciplinary team at Washington University in St. Louis developed a technique that delivered a therapeutic agent to the gliomas using focused ultrasound with very promising results. Dezhuang Ye, a doctoral student in the lab of Hong Chen, PhD, […]

WashU weekly Neuroscience publications

"Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus" (2021) Communications Biology Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus(2021) Communications Biology, 4 (1), art. no. 260, .  Jansson, D.a b c , Dieriks, V.B.b d , Rustenhoven, J.e f , Smyth, L.C.D.g h , Scotter, E.a b , Aalderink, M.a b , Feng, S.a b , Johnson, R.a b , Schweder, P.i , Mee, E.i , Heppner, P.j , Turner, C.k , Curtis, M.b d , […]

WashU weekly Neuroscience publications

“Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel” (2021) Nature Communications Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel (2021) Nature Communications, 12 (1), art. no. 926, .  Arnold, W.R.a , Carnevale, L.N.a , Xie, Z.b , Baylon, J.L.c , Tajkhorshid, E.c , Hu, H.b , Das, A.d e a Department of Biochemistry, University of Illinois Urbana-Champaign, […]

NIH awards $3.1 million grant for WashU, St. Jude ALS research

Scientists from Washington University in St. Louis and St. Jude Children’s Research Hospital have been awarded a five-year $3.1 million grant from the National Institute of Neurological Disorders and Stroke, an affiliate of the National Institutes of Health (NIH). Rohit Pappu, PhD, the Edwin H. Murty Professor of Engineering in the Department of Biomedical Engineering […]

WashU weekly Neuroscience publications

“A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors” (2021) Scientific Reports A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors (2021) Scientific Reports, 11 (1), art. no. 3858, .  Mattar, P.a f g , Jolicoeur, C.a , Dang, T.f g , Shah, S.f g , Clark, B.S.b c , Cayouette, M.a d e a Cellular Neurobiology Research Unit, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, QC H2W 1R7, Canada b John […]

WashU weekly Neuroscience publications

“Domain-general cognitive motivation: evidence from economic decision-making” (2021) Cognitive Research: Principles and Implications Domain-general cognitive motivation: evidence from economic decision-making (2021) Cognitive Research: Principles and Implications, 6 (1), art. no. 4, .  Crawford, J.L.a , Eisenstein, S.A.b c , Peelle, J.E.d , Braver, T.S.a a Department of Psychological and Brain Sciences, Washington University in St. Louis, 1 Brookings Dr, Box 1125, St. Louis, MO 63130, United […]

WashU weekly Neuroscience publications

“Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury” (2021) Nature Communications Improving hindlimb locomotor function by Non-invasive AAV-mediated manipulations of propriospinal neurons in mice with complete spinal cord injury (2021) Nature Communications, 12 (1), art. no. 781, .  Brommer, B.a , He, M.a , Zhang, Z.a , Yang, Z.a , Page, J.C.a , Su, J.a , Zhang, Y.a , […]

WashU weekly Neuroscience publications

"A 2020 view of tension-based cortical morphogenesis" (2021) Proceedings of the National Academy of Sciences of the United States of America A 2020 view of tension-based cortical morphogenesis(2021) Proceedings of the National Academy of Sciences of the United States of America, 117 (52), pp. 32868-32879.  van Essen, D.C. Department of Neuroscience, Washington University School of Medicine, Saint Louis, MO 63110, […]

Mechanism behind heartbeat regulation, heart function uncovered

Jianmin Cui, PhD, professor of biomedical engineering at the McKelvey School of Engineering, and Po wei (Billy) Kang, an MD/PhD student at the School of Medicine who conducts research in Cui’s lab, led an international team that revealed new details on how two biomolecules modulate opening and closing of the KCNQ1 potassium channel. This channel […]

WashU weekly Neuroscience publications

“‘It’s way more than just writing a prescription’: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder” (2021) Addiction Science and Clinical Practice “It’s way more than just writing a prescription”: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use […]

No more needles?

Blood draws are no fun. They hurt. Veins can burst, or even roll — like they’re trying to avoid the needle, too. Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen […]

WashU weekly Neuroscience publications

“Exercise routine change is associated with prenatal depression scores during the COVID-19 pandemic among pregnant women across the United States” (2021) PLoS ONE Exercise routine change is associated with prenatal depression scores during the COVID-19 pandemic among pregnant women across the United States (2021) PLoS ONE, 15 (12 December), art. no. e0243188, .  Gildner, T.E.a b , Laugier, E.J.a c , Thayer, Z.M.a c a Department of […]

WashU weekly Neuroscience publications

“A pilot investigation of emotional regulation difficulties and mindfulness-based strategies in manic and remitted bipolar I disorder and major depressive disorder” (2021) International Journal of Bipolar Disorders A pilot investigation of emotional regulation difficulties and mindfulness-based strategies in manic and remitted bipolar I disorder and major depressive disorder (2021) International Journal of Bipolar Disorders Musket, C.W.a , […]

Colored light investigated to control irregular heartbeat noninvasively

The National Institutes of Health (NIH) has awarded a $2.1 million four-year grant for cardiac optogenetics research led by Chao Zhou, PhD, associate professor of biomedical engineering at the McKelvey School of Engineering. Cardiac optogenetics allows researchers to control the opening and closing of ion channels, simulating different kinds of heart conditions, all the way […]

WashU weekly Neuroscience publications

"Destigmatizing Naloxone: Associations of Perceived Availability on Opioid Use Patterns" (2021) Annals of Emergency Medicine Destigmatizing Naloxone: Associations of Perceived Availability on Opioid Use Patterns(2021) Annals of Emergency Medicine, 77 (1), pp. 134-135.  Ellis, M.S., Kasper, Z.A., Cicero, T.J. Washington University in St. Louis, Department of Psychiatry, School of Medicine, St. Louis, MO, United States Document Type: LetterPublication Stage: FinalSource: Scopus "Prevalence, […]

WashU weekly Neuroscience publications

"Oral and maxillofacial surgeons’ assessment of the role of Pernkopf's atlas in surgical practice" (2021) Annals of Anatomy Oral and maxillofacial surgeons’ assessment of the role of Pernkopf’s atlas in surgical practice(2021) Annals of Anatomy, 234, art. no. 151614, .  Yee, A.a , Li, J.b , Lilly, J.b , Hildebrandt, S.c , Seidelman, W.E.d , Brown, D.e , Kopar, P.e , Coert, J.H.f , Mackinnon, S.E.a , Israel, H.A.b a Division of […]

WashU weekly Neuroscience publications

“Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy” (2021) Gait and Posture Midfoot and ankle motion during heel rise and gait are related in people with diabetes and peripheral neuropathy (2021) Gait and Posture, 84, pp. 38-44.  Jeong, H.-J., Mueller, M.J., Zellers, J.A., Hastings, M.K. Program in Physical Therapy, […]

New computational method validates images without ‘ground truth’

A realtor sends a prospective homebuyer a blurry photograph of a house taken from across the street. The homebuyer can compare it to the real thing — look at the picture, then look at the real house — and see that the bay window is actually two windows close together, the flowers out front are […]

WashU weekly Neuroscience publications

“Cerebrospinal fluid Aβ42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability” (2021) Neurobiology of Aging Cerebrospinal fluid Aβ42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability (2021) Neurobiology of Aging, 98, pp. 116-123.  Meeker, K.L.a b , Ances, B.M.b , Gordon, B.A.c , Rudolph, C.W.a , Luckett, P.b , Balota, D.A.d , Morris, J.C.b , Fagan, A.M.b , Benzinger, T.L.c , Waring, J.D.a […]

Zhou to pursue novel imaging method with Stein Innovation Award from Research to Prevent Blindness

Chao Zhou, PhD a Washington University in St. Louis engineer who develops novel optical imaging technologies for biomedical applications, has been awarded a Stein Innovation Award from Research to Prevent Blindness to pursue development of novel imaging methods for diagnostic uses. The three-year, $300,000 award provides flexible funds to scientists engaged in research working to […]

Bayly named inaugural Lee Hunter Distinguished Professor

Philip V. Bayly, PhD, an innovative researcher of waves and oscillations in the mechanics of cells and biological tissues, has been named the inaugural Lee Hunter Distinguished Professor in the McKelvey School of Engineering at Washington University in St. Louis. Bayly, who has been chair of the Department of Mechanical Engineering & Materials Science since […]

WashU weekly Neuroscience publications

“Fronto-cerebellar connectivity mediating cognitive processing speed” (2021) NeuroImage Fronto-cerebellar connectivity mediating cognitive processing speed (2021) NeuroImage, 226, art. no. 117556, . Wong, C.H.Y.a b c , Liu, J.d e f l , Lee, T.M.C.b c j k , Tao, J.d e l , Wong, A.W.K.g h , Chau, B.K.H.a i , Chen, L.d e l , Chan, C.C.H.a i a Applied Cognitive Neuroscience Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong b Laboratory of Neuropsychology and Human Neuroscience, Department of […]

Chan Zuckerberg Initiative names two WashU groups Frontiers of Imaging grantees

The Chan Zuckerberg Initiative (CZI) on Dec. 2 announced two research groups led by Washington University in St. Louis faculty were named Frontiers of Imaging grantees. Both groups will focus on the brain — where current imaging techniques can penetrate just about the depth of a couple of human hairs — with $1 million each […]

WashU weekly Neuroscience publications

“Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants” (2020) Developmental Cognitive Neuroscience Prenatal stress exposure and multimodal assessment of amygdala–medial prefrontal cortex connectivity in infants (2020) Developmental Cognitive Neuroscience, 46, art. no. 100877, . Humphreys, K.L.a , Camacho, M.C.b , Roth, M.C.a , Estes, E.C.a a Vanderbilt University, Department of Psychology and Human Development, 230 Appleton Place, #552, Nashville, […]

AAAS names 7 Washington University faculty as 2020 fellows

Seven faculty members at Washington University in St. Louis are among 489 new fellows selected by the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society. And four of those seven are School of Medicine faculty. The newly selected fellows from the medical school are: Aaron DiAntonio, MD, PhD; David H. Gutmann, […]

WashU weekly Neuroscience publications

"Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the randomised, placebo-controlled, phase 3 trial" (2020) The Lancet Neurology Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the […]

WashU weekly Neuroscience publications

“Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study” (2021) Neurobiology of Aging Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study (2021) Neurobiology of Aging, 97, pp. 65-72. Walker, K.A.a , Chawla, S.b , Nogueras-Ortiz, C.b , Coresh, J.c , Sharrett, A.R.c , Wong, D.F.d , Jack, C.R., Jr.e , Spychalla, […]

WashU weekly Neuroscience publications

"Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage" (2021) Brain Research Anesthetic and subanesthetic doses of isoflurane conditioning provides strong protection against delayed cerebral ischemia in a mouse model of subarachnoid hemorrhage(2021) Brain Research, 1750, art. no. 147169, .  Athiraman, U.a , Liu, M.a , Jayaraman, K.b , Yuan, J.a , […]

Board of Trustees grants faculty appointments, promotions

At the Washington University in St. Louis Board of Trustees meeting Oct. 2, several faculty members were appointed or promoted with tenure or granted tenure, effective that day unless otherwise indicated… …Promotion with tenure Luis F.Z. Batista to associate professor of medicine and of developmental biology at the School of Medicine (tenure effective Jan. 1); Nico […]

WashU weekly Neuroscience publications

“N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury” (2021) Experimental Neurology N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury (2021) Experimental Neurology, 335, art. no. 113507, . Celorrio, M., Rhodes, J., Vadivelu, S., Davies, M., Friess, S.H. Division of Critical Care Medicine, Department of Pediatrics, Washington University in St. Louis School of Medicine, One […]

WashU weekly Neuroscience publications

“Relationships between accelerometry and general compensatory movements of the upper limb after stroke” (2020) Journal of NeuroEngineering and Rehabilitation Relationships between accelerometry and general compensatory movements of the upper limb after stroke (2020) Journal of NeuroEngineering and Rehabilitation, 17 (1), art. no. 138, . Barth, J.a , Klaesner, J.W.a d , Lang, C.E.a b c a Washington University School of Medicine, Program in Physical Therapy, St. Louis, […]

Pappu, collaborators awarded $7.5 million MURI award

Rohit Pappu, the Edwin H. Murty Professor of Engineering at the McKelvey School of Engineering at Washington University in St. Louis, is part of multi-institution team to receive a highly competitive 2020 Multidisciplinary University Research Initiative (MURI) award from the Department of Defense. The five-year $7.5 million grant is shared with three other universities and is aimed […]

WashU weekly Neuroscience publications

“Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells” (2020) Brain Research Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells (2020) Brain Research, 1749, art. no. 147139, . Matsuhisa, K.a b , Cai, L.a , Saito, A.a b , Sakaue, F.b , Kamikawa, Y.b , Fujiwara, S.b , Asada, R.c , Kudo, Y.d , Imaizumi, K.a a Department of Biochemistry, […]

WashU weekly Neuroscience publications

“Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders” (2021) Journal of Affective Disorders Depression and Buprenorphine Treatment in Patients with Non-cancer Pain and Prescription Opioid Dependence without Comorbid Substance Use Disorders (2021) Journal of Affective Disorders, 278, pp. 563-569. Scherrer, J.F.a , Salas, J.a , Grucza, R.a , Sullivan, M.D.b , Lustman, P.J.c d , […]

WashU weekly Neuroscience publications

“Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis” (2020) Journal of Ophthalmic Inflammation and Infection Incidence of uveitis and macular edema among patients taking fingolimod 0.5 mg for multiple sclerosis (2020) Journal of Ophthalmic Inflammation and Infection, 10 (1), art. no. 24, . Sonne, S.J.a , Smith, B.T.b c a St. Louis University School of Medicine, St. […]

WashU weekly Neuroscience publications

“Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents” (2020) Journal of Controlled Release Characterization of focused ultrasound-mediated brainstem delivery of intranasally administered agents (2020) Journal of Controlled Release, 328, pp. 276-285. Ye, D.a , Luan, J.a , Pang, H.b , Yang, Y.b , Nazeri, A.c , Rubin, J.B.d e , Chen, H.b f a Department of Mechanical Engineering and Materials Science, Washington University in St. Louis, […]

WashU weekly Neuroscience publications

“Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites” (2020) Molecular Pharmacology Analysis of Modulation of the ρ1 GABAA Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites (2020) Molecular Pharmacology, 98 (4), pp. 280-291.  Germann, A.L., Reichert, D.E., Burbridge, A.B., Pierce, S.R., […]

WashU weekly Neuroscience publications

“Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction” (2020) Nature Communications Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction (2020) Nature Communications, 11 (1), art. no. 4358, . Ozawa, M.a b , Davis, P.a b c e , Ni, J.a , Maguire, J.a , Papouin, T.a d , Reijmers, L.a a Department of Neuroscience, School of Medicine, Tufts University, Boston, MA, United States b Graduate Program in […]

WashU weekly Neuroscience publications

“Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder” (2020) Translational Psychiatry Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder (2020) Translational Psychiatry, 10 (1), art. no. 298, . Lopes, F.L.a , Zhu, K.a , Purves, K.L.b , Song, C.a , Ahn, K.a , Hou, L.a , Akula, N.a , Kassem, L.a , Bergen, S.E.c , Landen, M.c d , Veras, A.B.e , Nardi, […]

WashU weekly Neuroscience publications

“Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice” (2020) Scientific Reports Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice (2020) Scientific Reports, 10 (1), art. no. 13630, . Akkaya, M.a , Bansal, A.b e , Sheehan, P.W.a f , Pena, […]

Using light’s properties to indirectly see inside a cell membrane

For those not involved in chemistry or biology, picturing a cell likely brings to mind several discrete, blob-shaped objects; maybe the nucleus, mitochondria, ribosomes and the like. There’s one part that’s often overlooked, save perhaps a squiggly line indicating the cell’s border: the membrane. But its role as gatekeeper is an essential one, and a […]

Researchers one step closer to bomb-sniffing cyborg locusts

If you want to enhance a locust to be used as a bomb-sniffing bug, there are a few technical challenges that need solving before sending it into the field. Is there some way to direct the locust — to tell it where to go to do its sniffing? And because the locusts can’t speak (yet), […]

WashU weekly Neuroscience publications

“Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity” (2020) Nature Communications Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity (2020) Nature Communications, 11 (1), art. no. 3996, . Bariselli, S.a d , Miyazaki, N.L.a , Creed, M.C.b c , Kravitz, A.V.a c a National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States b Washington University Pain Center, St Louis, MO 63110, United States c Departments of Psychiatry, […]