WashU weekly Neuroscience publications

“Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear” (2020) Hearing Research Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear (2020) Hearing Research, 385, art. no. 107839, .  Wan, L.a , Lovett, M.b , Warchol, M.E.c , Stone, J.S.a a Virginia Merrill Bloedel Hearing […]

WashU weekly Neuroscience publications

“A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease” (2020) Neurobiology of Disease A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson’s disease (2020) Neurobiology of Disease, 134, art. no. 104647, .  Aflaki, E.a , Stubblefield, B.K.a , McGlinchey, R.P.b , McMahon, B.a , Ory, D.S.c , Sidransky, E.a a Section of Molecular Neurogenetics, National Human Genome Research […]

WashU weekly Neuroscience publications

“Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems” (2020) Bone Hematopoietic stem cell transplantation-induced bone remodeling in autosomal recessive osteopetrosis: Interaction between skeleton and hematopoietic and sensory nervous systems (2020) Bone, 130, art. no. 115144, .  Maximova, N.a , Zennaro, F.b , Gregori, M.a , Boz, G.c , Zanon, […]

WashU weekly Neuroscience publications

“Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis” (2019) Journal of Anxiety Disorders Changes in Dosing and Dose Timing of D-Cycloserine Explain Its Apparent Declining Efficacy for Augmenting Exposure Therapy for Anxiety-related Disorders: An Individual Participant-data Meta-analysis (2019) Journal of […]

WashU weekly Neuroscience publications

“Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction” (2020) Early Human Development Progressive anemia of prematurity is associated with a critical increase in cerebral oxygen extraction (2020) Early Human Development, 140, art. no. 104891, .  Whitehead, H.V.a , Vesoulis, Z.A.a , Maheshwari, A.b , Rambhia, A.a , Mathur, A.M.c a Department of Pediatrics, Division of […]

WashU weekly Neuroscience publications

“Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex” (2020) Neurobiology of Disease Hypothalamic orexin and mechanistic target of rapamycin activation mediate sleep dysfunction in a mouse model of tuberous sclerosis complex (2020) Neurobiology of Disease, 134, art. no. 104615, .  Zhang, B.a , Guo, D.a , Han, L.a , […]

Grant to help train researchers on mental health disparities in U.S., abroad

Researchers at Washington University in St. Louis have been awarded a grant from the National Institute on Minority Health and Health Disparities of the National Institutes of Health (NIH) to train young scientists to recognize, investigate and work toward correcting disparities in access to mental health care in the United States and sub-Saharan Africa. Although […]

WashU weekly Neuroscience publications

“Identifying reproducible individual differences in childhood functional brain networks: An ABCD study” (2019) Developmental Cognitive Neuroscience Identifying reproducible individual differences in childhood functional brain networks: An ABCD study (2019) Developmental Cognitive Neuroscience, 40, art. no. 100706, .  Marek, S.a , Tervo-Clemmens, B.b , Nielsen, A.N.c , Wheelock, M.D.a , Miller, R.L.d , Laumann, T.O.a , Earl, E.f , Foran, W.W.e […]

WashU weekly Neuroscience publications

“Alzheimer Disease: An Update on Pathobiology and Treatment Strategies” (2019) Cell Alzheimer Disease: An Update on Pathobiology and Treatment Strategies (2019) Cell, 179 (2), pp. 312-339.  Long, J.M., Holtzman, D.M. Department of Neurology, Hope Center for Neurological Disorders, Charles F. and Joanne Knight Alzheimer’s Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, United States Abstract Long […]

WashU weekly Neuroscience publications

“Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers” (2019) Neurobiology of Aging Tracking white matter degeneration in asymptomatic and symptomatic MAPT mutation carriers (2019) Neurobiology of Aging, 83, pp. 54-62.  Chen, Q.a b , Boeve, B.F.c , Schwarz, C.G.b , Reid, R.b , Tosakulwong, N.d , Lesnick, T.G.d , Bove, J.e , Brannelly, P.f , Brushaber, […]

WashU weekly Neuroscience publications

“The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability” (2019) NeuroImage The community structure of functional brain networks exhibits scale-specific patterns of inter- and intra-subject variability (2019) NeuroImage, 202, art. no. 115990, .  Betzel, R.F.a b c , Bertolero, M.A.a , Gordon, E.M.d e , Gratton, C.f g , Dosenbach, N.U.F.f h i , […]

WashU weekly Neuroscience publications

“Pioglitazone improves working memory performance when administered in chronic TBI” (2019) Neurobiology of Disease Pioglitazone improves working memory performance when administered in chronic TBI (2019) Neurobiology of Disease, 132, art. no. 104611, .  McGuire, J.L.a , Correll, E.A.a , Lowery, A.C.b , Rhame, K.c , Anwar, F.N.d , McCullumsmith, R.E.e , Ngwenya, L.B.a f a Department of Neurosurgery, University of Cincinnati, […]

WashU weekly Neuroscience publications

“Large posttraumatic stress disorder improvement and antidepressant medication adherence” (2020) Journal of Affective Disorders Large posttraumatic stress disorder improvement and antidepressant medication adherence (2020) Journal of Affective Disorders, 260, pp. 119-123.  Salas, J.a b , Scherrer, J.F.a b , Tuerk, P.c , van den Berk-Clark, C.a , Chard, K.M.d , Schneider, F.D.e , Schnurr, P.P.f , Friedman, M.J.f , […]

CAPA Clinic shows promising results for addiction treatment patients in St. Louis

The Community Academic Partnership on Addiction (CAPA) Clinic, a partnership between the Brown School and Preferred Family Healthcare (PFH), was able to increase treatment completion rates by 11% over a six-month time period. “This is excellent work and very strong findings,” said Mary McKay, the Neidorff Family and Centene Corporation Dean of the Brown School at Washington University […]

WashU weekly Neuroscience publications

“Alternative ecological strategies lead to avian brain size bimodality in variable habitats” (2019) Nature Communications Alternative ecological strategies lead to avian brain size bimodality in variable habitats (2019) Nature Communications, 10 (1), art. no. 3818, .  Fristoe, T.S.a b , Botero, C.A.b a Department of Biology, University of Konstanz, Universitätsstraße 10, Konstanz, 78464, Germany b Department of Biology, Washington University in St. Louis, […]

Cindy Brantmeier named inaugural WashU Faculty Fellow in International Research

Dear Colleagues, I am pleased to announce that Dr. Cindy Brantmeier has been selected to serve as the first Faculty Fellow in International Research for the School of Medicine and Danforth Campus. The Faculty Fellow in International Research will advise faculty on conducting international research and achieving effective collaborations with international partners that are compliant […]

WashU weekly Neuroscience publications

“Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter” (2019) Scientific Reports Diffusion Tensor Model links to Neurite Orientation Dispersion and Density Imaging at high b-value in Cerebral Cortical Gray Matter (2019) Scientific Reports, 9 (1), art. no. 12246, .  Fukutomi, H.a b , Glasser, M.F.c d , Murata, K.e , […]

$785K NIMH grant awarded to Brown School’s Mary McKay

Mary McKay, the Neidorff Family and Centene Corporation Dean of the Brown School, has received a five-year, $785,000 grant from the National Institutes of Health (NIH)’s National Institute of Mental Health for a project titled “Navigating Resource-Constrained Systems and Communities to Promote the Behavioral Health of Black Youth.” Sean Joe, the Benjamin E. Youngdahl Professor of Social Development […]

WashU weekly Neuroscience publications

"Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex" (2019) Scientific Reports Differential neural dynamics underling pragmatic and semantic affordance processing in macaque ventral premotor cortex(2019) Scientific Reports, 9 (1), art. no. 11700, .  Maranesi, M.a , Bruni, S.a b , Livi, A.a c , Donnarumma, F.d , Pezzulo, G.d , Bonini, L.a a Department of Medicine […]

WashU weekly Neuroscience publications

“Sleep disturbances in Wolfram syndrome” (2019) Orphanet Journal of Rare Diseases Sleep disturbances in Wolfram syndrome (2019) Orphanet Journal of Rare Diseases, 14 (1), art. no. 188, .  Licis, A.a , Davis, G.d e , Eisenstein, S.A.b c , Lugar, H.M.b , Hershey, T.a b c a Department of Neurology, Washington University, School of Medicine, Campus Box 8111, 660 South Euclid Ave, […]

WashU weekly Neuroscience publications

“Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia” (2019) Scientific Reports Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia (2019) Scientific Reports, 9 (1), art. no. 10854, .  Bonham, L.W.a b , Steele, N.Z.R.a , Karch, C.M.c […]

WashU weekly Neuroscience publications

“A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings” (2019) Journal of Substance Abuse Treatment A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings (2019) Journal of Substance Abuse Treatment, 104, pp. 135-143.  Presnall, N.J.a b , Wolf, D.A.P.S.a , Brown, D.S.a , Beeler-Stinn, S.a , Grucza, R.A.b a Brown School of […]

WashU weekly Neuroscience publications

“CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease)” (2019) Scientific Reports CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease) (2019) Scientific Reports, 9 (1), art. no. 9891, .  Eaton, S.L.a , Proudfoot, C.a , Lillico, S.G.a , Skehel, P.b c , Kline, R.A.a , Hamer, K.e , Rzechorzek, N.M.d […]

WashU weekly Neuroscience publications

“A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation” (2019) Molecular Genetics and Metabolism Reports A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation (2019) Molecular Genetics and Metabolism Reports, 20, art. no. 100484, .  Ahmed, A.a , Ou, L.b , Rudser, K.c , […]

WashU weekly Neuroscience publications

“Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns” (2019) Nature Communications Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns (2019) Nature Communications, 10 (1), art. no. 2548, .  Czamara, D.a , Eraslan, G.b c , Page, C.M.d e , Lahti, J.f g , Lahti-Pulkkinen, M.f h , Hämäläinen, E.i […]

WashU weekly Neuroscience publications

“High-fidelity mapping of repetition-related changes in the parietal memory network” (2019) NeuroImage High-fidelity mapping of repetition-related changes in the parietal memory network (2019) NeuroImage, 199, pp. 427-439.  Gilmore, A.W.a , Nelson, S.M.h i j , Laumann, T.O.b c , Gordon, E.M.h i , Berg, J.J.a , Greene, D.J.c d , Gratton, C.b , Nguyen, A.L.b , Ortega, M.b , […]

WashU weekly Neuroscience publications

“A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ” (2019) Nature Communications A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ (2019) Nature Communications, 10 (1), art. no. 2448, .  Kim, W.S.a , Shalit, Z.A.a , Nguyen, S.M.b , Schoepke, E.c , Eastman, A.d , Burris, T.P.c , Gaur, A.B.b , Micalizio, G.C.a a Dartmouth College, Department of […]

Thorp to conclude term as Washington University provost

Holden Thorp, provost at Washington University in St. Louis, will leave his position effective July 15, according to Chancellor Andrew D. Martin. Thorp, who has served in his current role since 2013, plans to take a one-year sabbatical and then return to the university in a newly created leadership role in the drug discovery and […]

WashU weekly Neuroscience publications

“Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling” (2019) Current Opinion in Neurobiology Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling (2019) Current Opinion in Neurobiology, 59, pp. 59-68.  Goodman, J.V.a b , Bonni, A.a a Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States b Medical Scientist Training Program, Washington […]

WashU weekly Neuroscience publications

“Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms” (2019) Nature Communications Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms (2019) Nature Communications, 10 (1), art. no. 2246, .  Li, P.a , Marshall, L.a , Oh, G.b , Jakubowski, J.L.a , Groot, D.b , He, Y.c , Wang, […]

E3 Nutrition Lab Links Child Nutrition, Economics and Evolution

A transdisciplinary laboratory at the Brown School is undertaking research across the world to address “hidden hunger”— poverty-related nutritional deficiencies in mothers and young children. The founder and director of the E3 Nutrition Lab is Lora Iannotti, associate professor and associate dean for public health. The three “E”s represent the lab’s principles for nutrition interventions: […]

WashU weekly Neuroscience publications

“Classification of temporal ICA components for separating global noise from fMRI data: Reply to Power” (2019) NeuroImage Classification of temporal ICA components for separating global noise from fMRI data: Reply to Power (2019) NeuroImage, 197, pp. 435-438.  Glasser, M.F.a b c , Coalson, T.S.a , Bijsterbosch, J.D.d , Harrison, S.J.d e , Harms, M.P.f , Anticevic, A.g , Van […]

WashU weekly Neuroscience publications

“Author Correction: TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells (Scientific Reports, (2017), 7, 1, (11569), 10.1038/s41598-017-11885-8)” (2019) Scientific Reports Author Correction: TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells (Scientific Reports, (2017), 7, 1, (11569), 10.1038/s41598-017-11885-8) (2019) Scientific Reports, 9 (1), art. no. 6400, .  Guo, P.a , Yu, Y.b […]

WashU weekly Neuroscience publications

“Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry” (2019) Scientific Reports Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry (2019) Scientific Reports, 9 (1), art. no. 6010, .  Lugar, H.M.a , Koller, J.M.a , Rutlin, J.a , Eisenstein, S.A.a , Neyman, O.a , Narayanan, A.a , Chen, L.c , Shimony, J.S.b , Hershey, […]

WashU weekly Neuroscience publications

“The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF)” (2019) Journal of Psychiatric Research The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF) (2019) Journal of Psychiatric Research, 113, pp. 125-136.  Sackeim, H.A.a , Aaronson, S.T.b , Bunker, M.T.c , Conway, C.R.d , […]

WashU weekly Neuroscience publications

“The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain” (2019) Nature Communications The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain (2019) Nature Communications, 10 (1), art. no. 1417, .  Karolis, V.R., Corbetta, M., Thiebaut de Schotten, M. Abstract Functional lateralisation is a fundamental principle of the human brain. […]

WashU weekly Neuroscience publications

“Resting state functional connectivity predictors of treatment response to electroconvulsive therapy in depression” (2019) Scientific Reports Resting state functional connectivity predictors of treatment response to electroconvulsive therapy in depression (2019) Scientific Reports, 9 (1), art. no. 5071, .  Moreno-Ortega, M.a b , Prudic, J.a , Rowny, S.a , Patel, G.H.a , Kangarlu, A.d , Lee, S.c , Grinband, J.a , Palomo, […]

Board of Trustees grants faculty appointments, promotions

At the Washington University in St. Louis Board of Trustees meeting March 1, the following faculty were appointed with tenure, promoted with tenure or granted tenure, effective July 1 unless otherwise noted. Appointment with tenure Kevin Michael Bennett as associate professor of radiology at the School of Medicine (tenure effective March 1); and Neal Patwari as professor […]

WashU weekly Neuroscience publications

“Regeneration associated transcriptional signature of retinal microglia and macrophages” (2019) Scientific Reports Regeneration associated transcriptional signature of retinal microglia and macrophages (2019) Scientific Reports, 9 (1), art. no. 4768, .  Mitchell, D.M.a , Sun, C.a b , Hunter, S.S.c , New, D.D.c , Stenkamp, D.L.a a Department of Biological Sciences, University of Idaho, Moscow, ID 83844, United States b Ophthalmology, Washington University in […]

Do business concerns keep doctors from treating opioid addiction?

One morning last week as I arrived at our new addiction treatment center, the CAPA Clinic in St. Louis, one of the social work student interns I supervise couldn’t wait to tell me about the “excitement” they’d experienced in the few hours the clinic had been open for the day: a patient had been stabbed, another was […]

WashU weekly Neuroscience publications

“Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice” (2019) Scientific Reports Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice (2019) Scientific Reports, 9 (1), art. no. 4379, . Wozniak, D.F., Valnegri, P., Dearborn, J.T., Fowler, S.C., Bonni, A. Document Type: Article Publication Stage: Final Source: Scopus Access Type: Open Access “A […]

Medications to treat opioid addiction are effective, though not widely used

With more than 2 million Americans suffering from an opioid use disorder and the escalating rate of deaths from opioid overdoses reaching about 130 per day, efforts to date have had little impact in curbing this crisis across the country. As a result, a committee of the National Academies of Sciences, Engineering and Medicine released on March […]

WashU weekly Neuroscience publications

“The immediate benefits and long-term consequences of briefly presented masked primes on episodic recollection” (2019) Journal of Memory and Language The immediate benefits and long-term consequences of briefly presented masked primes on episodic recollection (2019) Journal of Memory and Language, 106, pp. 77-94.  Maddox, G.B.a , Balota, D.A.b , Kumar, A.A.b , Millar, P.R.b , Churchill, L.b a Department of […]

WashU weekly Neuroscience publications

“Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits” (2019) Scientific Reports Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits (2019) Scientific Reports, 9 (1), art. no. 2779, .  Maloney, S.E.a d f , Yuede, C.M.a b , […]

WashU weekly Neuroscience publications

“Correction to: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language (Nature Communications, (2018), 9, 1, (4619), 10.1038/s41467-018-06014-6)” (2019) Nature Communications Correction to: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language (Nature Communications, (2018), 9, 1, (4619), 10.1038/s41467-018-06014-6) (2019) Nature Communications, 10 (1), art. no. 883, .  Blok, […]

WashU Expert: Want to stop e-cig epidemic? Don’t forget state, local policies

Tobacco control experts Douglas Luke and Todd Combs of Washington University in St. Louis would welcome regulation of e-cigarette commercials on television and radio. But an advertising ban, as recently suggested by a member of the Federal Communications Commission (FCC), should be part of a broader plan to curb the vaping epidemic among America’s youth, […]

WashU weekly Neuroscience publications

“Predicting Alzheimer’s disease progression using multi-modal deep learning approach” (2019) Scientific Reports Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) Scientific Reports, 9 (1), art. no. 1952, .  Lee, G.a b , Nho, K.c d , Kang, B.a , Sohn, K.-A.a , Kim, D.b e , Weiner, M.W.f , Aisen, P.g , Petersen, R.h , Jack, C.R., Jr.h , […]

WashU weekly Neuroscience publications

“Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles” (2019) Channels (Austin, Tex.) Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles (2019) Channels (Austin, Tex.), 13 (1), pp. 72-87.  Wang, W.a , Mellor, R.L.a , Nerbonne, J.M.a b , Balke, C.W.a […]

WashU weekly Neuroscience publications

“Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease” (2019) Stroke Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease (2019) Stroke, 50 (2), pp. 266-273.  Guilliams, K.P.a b , Fields, M.E.b , Dowling, M.M.c a From the Department of Neurology (K.P.G.), Washington University School […]

WashU weekly Neuroscience publications

“Neuronal evidence for good-based economic decisions under variable action costs” (2019) Nature Communications Neuronal evidence for good-based economic decisions under variable action costs (2019) Nature Communications, 10 (1), art. no. 393, .  Cai, X.a b c d , Padoa-Schioppa, C.a e f a Department of Neuroscience, Washington University in St Louis, St Louis, MO 63110, United States b NYU Shanghai, 1555 Century Avenue, […]