WashU weekly Neuroscience publications

“Sleep disturbances in Wolfram syndrome” (2019) Orphanet Journal of Rare Diseases Sleep disturbances in Wolfram syndrome (2019) Orphanet Journal of Rare Diseases, 14 (1), art. no. 188, .  Licis, A.a , Davis, G.d e , Eisenstein, S.A.b c , Lugar, H.M.b , Hershey, T.a b c a Department of Neurology, Washington University, School of Medicine, Campus Box 8111, 660 South Euclid Ave, […]

WashU weekly Neuroscience publications

“Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia” (2019) Scientific Reports Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia (2019) Scientific Reports, 9 (1), art. no. 10854, .  Bonham, L.W.a b , Steele, N.Z.R.a , Karch, C.M.c […]

WashU weekly Neuroscience publications

“A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings” (2019) Journal of Substance Abuse Treatment A comparison of buprenorphine and psychosocial treatment outcomes in psychosocial and medical settings (2019) Journal of Substance Abuse Treatment, 104, pp. 135-143.  Presnall, N.J.a b , Wolf, D.A.P.S.a , Brown, D.S.a , Beeler-Stinn, S.a , Grucza, R.A.b a Brown School of […]

WashU weekly Neuroscience publications

“CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease)” (2019) Scientific Reports CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease) (2019) Scientific Reports, 9 (1), art. no. 9891, .  Eaton, S.L.a , Proudfoot, C.a , Lillico, S.G.a , Skehel, P.b c , Kline, R.A.a , Hamer, K.e , Rzechorzek, N.M.d […]

WashU weekly Neuroscience publications

“A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation” (2019) Molecular Genetics and Metabolism Reports A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation (2019) Molecular Genetics and Metabolism Reports, 20, art. no. 100484, .  Ahmed, A.a , Ou, L.b , Rudser, K.c , […]

WashU weekly Neuroscience publications

“Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns” (2019) Nature Communications Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns (2019) Nature Communications, 10 (1), art. no. 2548, .  Czamara, D.a , Eraslan, G.b c , Page, C.M.d e , Lahti, J.f g , Lahti-Pulkkinen, M.f h , Hämäläinen, E.i […]

WashU weekly Neuroscience publications

“High-fidelity mapping of repetition-related changes in the parietal memory network” (2019) NeuroImage High-fidelity mapping of repetition-related changes in the parietal memory network (2019) NeuroImage, 199, pp. 427-439.  Gilmore, A.W.a , Nelson, S.M.h i j , Laumann, T.O.b c , Gordon, E.M.h i , Berg, J.J.a , Greene, D.J.c d , Gratton, C.b , Nguyen, A.L.b , Ortega, M.b , […]

WashU weekly Neuroscience publications

“A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ” (2019) Nature Communications A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ (2019) Nature Communications, 10 (1), art. no. 2448, .  Kim, W.S.a , Shalit, Z.A.a , Nguyen, S.M.b , Schoepke, E.c , Eastman, A.d , Burris, T.P.c , Gaur, A.B.b , Micalizio, G.C.a a Dartmouth College, Department of […]

Thorp to conclude term as Washington University provost

Holden Thorp, provost at Washington University in St. Louis, will leave his position effective July 15, according to Chancellor Andrew D. Martin. Thorp, who has served in his current role since 2013, plans to take a one-year sabbatical and then return to the university in a newly created leadership role in the drug discovery and […]

WashU weekly Neuroscience publications

“Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling” (2019) Current Opinion in Neurobiology Regulation of neuronal connectivity in the mammalian brain by chromatin remodeling (2019) Current Opinion in Neurobiology, 59, pp. 59-68.  Goodman, J.V.a b , Bonni, A.a a Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, United States b Medical Scientist Training Program, Washington […]

WashU weekly Neuroscience publications

“Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms” (2019) Nature Communications Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer’s disease pathology and cognitive symptoms (2019) Nature Communications, 10 (1), art. no. 2246, .  Li, P.a , Marshall, L.a , Oh, G.b , Jakubowski, J.L.a , Groot, D.b , He, Y.c , Wang, […]

E3 Nutrition Lab Links Child Nutrition, Economics and Evolution

A transdisciplinary laboratory at the Brown School is undertaking research across the world to address “hidden hunger”— poverty-related nutritional deficiencies in mothers and young children. The founder and director of the E3 Nutrition Lab is Lora Iannotti, associate professor and associate dean for public health. The three “E”s represent the lab’s principles for nutrition interventions: […]

WashU weekly Neuroscience publications

“Classification of temporal ICA components for separating global noise from fMRI data: Reply to Power” (2019) NeuroImage Classification of temporal ICA components for separating global noise from fMRI data: Reply to Power (2019) NeuroImage, 197, pp. 435-438.  Glasser, M.F.a b c , Coalson, T.S.a , Bijsterbosch, J.D.d , Harrison, S.J.d e , Harms, M.P.f , Anticevic, A.g , Van […]

WashU weekly Neuroscience publications

“Author Correction: TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells (Scientific Reports, (2017), 7, 1, (11569), 10.1038/s41598-017-11885-8)” (2019) Scientific Reports Author Correction: TGF-β1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells (Scientific Reports, (2017), 7, 1, (11569), 10.1038/s41598-017-11885-8) (2019) Scientific Reports, 9 (1), art. no. 6400, .  Guo, P.a , Yu, Y.b […]

WashU weekly Neuroscience publications

“Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry” (2019) Scientific Reports Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry (2019) Scientific Reports, 9 (1), art. no. 6010, .  Lugar, H.M.a , Koller, J.M.a , Rutlin, J.a , Eisenstein, S.A.a , Neyman, O.a , Narayanan, A.a , Chen, L.c , Shimony, J.S.b , Hershey, […]

WashU weekly Neuroscience publications

“The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF)” (2019) Journal of Psychiatric Research The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF) (2019) Journal of Psychiatric Research, 113, pp. 125-136.  Sackeim, H.A.a , Aaronson, S.T.b , Bunker, M.T.c , Conway, C.R.d , […]

WashU weekly Neuroscience publications

“The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain” (2019) Nature Communications The architecture of functional lateralisation and its relationship to callosal connectivity in the human brain (2019) Nature Communications, 10 (1), art. no. 1417, .  Karolis, V.R., Corbetta, M., Thiebaut de Schotten, M. Abstract Functional lateralisation is a fundamental principle of the human brain. […]

WashU weekly Neuroscience publications

“Resting state functional connectivity predictors of treatment response to electroconvulsive therapy in depression” (2019) Scientific Reports Resting state functional connectivity predictors of treatment response to electroconvulsive therapy in depression (2019) Scientific Reports, 9 (1), art. no. 5071, .  Moreno-Ortega, M.a b , Prudic, J.a , Rowny, S.a , Patel, G.H.a , Kangarlu, A.d , Lee, S.c , Grinband, J.a , Palomo, […]

Board of Trustees grants faculty appointments, promotions

At the Washington University in St. Louis Board of Trustees meeting March 1, the following faculty were appointed with tenure, promoted with tenure or granted tenure, effective July 1 unless otherwise noted. Appointment with tenure Kevin Michael Bennett as associate professor of radiology at the School of Medicine (tenure effective March 1); and Neal Patwari as professor […]

WashU weekly Neuroscience publications

“Regeneration associated transcriptional signature of retinal microglia and macrophages” (2019) Scientific Reports Regeneration associated transcriptional signature of retinal microglia and macrophages (2019) Scientific Reports, 9 (1), art. no. 4768, .  Mitchell, D.M.a , Sun, C.a b , Hunter, S.S.c , New, D.D.c , Stenkamp, D.L.a a Department of Biological Sciences, University of Idaho, Moscow, ID 83844, United States b Ophthalmology, Washington University in […]

Do business concerns keep doctors from treating opioid addiction?

One morning last week as I arrived at our new addiction treatment center, the CAPA Clinic in St. Louis, one of the social work student interns I supervise couldn’t wait to tell me about the “excitement” they’d experienced in the few hours the clinic had been open for the day: a patient had been stabbed, another was […]

WashU weekly Neuroscience publications

“Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice” (2019) Scientific Reports Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice (2019) Scientific Reports, 9 (1), art. no. 4379, . Wozniak, D.F., Valnegri, P., Dearborn, J.T., Fowler, S.C., Bonni, A. Document Type: Article Publication Stage: Final Source: Scopus Access Type: Open Access “A […]

Medications to treat opioid addiction are effective, though not widely used

With more than 2 million Americans suffering from an opioid use disorder and the escalating rate of deaths from opioid overdoses reaching about 130 per day, efforts to date have had little impact in curbing this crisis across the country. As a result, a committee of the National Academies of Sciences, Engineering and Medicine released on March […]

WashU weekly Neuroscience publications

“The immediate benefits and long-term consequences of briefly presented masked primes on episodic recollection” (2019) Journal of Memory and Language The immediate benefits and long-term consequences of briefly presented masked primes on episodic recollection (2019) Journal of Memory and Language, 106, pp. 77-94.  Maddox, G.B.a , Balota, D.A.b , Kumar, A.A.b , Millar, P.R.b , Churchill, L.b a Department of […]

WashU weekly Neuroscience publications

“Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits” (2019) Scientific Reports Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits (2019) Scientific Reports, 9 (1), art. no. 2779, .  Maloney, S.E.a d f , Yuede, C.M.a b , […]

WashU weekly Neuroscience publications

“Correction to: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language (Nature Communications, (2018), 9, 1, (4619), 10.1038/s41467-018-06014-6)” (2019) Nature Communications Correction to: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language (Nature Communications, (2018), 9, 1, (4619), 10.1038/s41467-018-06014-6) (2019) Nature Communications, 10 (1), art. no. 883, .  Blok, […]

WashU Expert: Want to stop e-cig epidemic? Don’t forget state, local policies

Tobacco control experts Douglas Luke and Todd Combs of Washington University in St. Louis would welcome regulation of e-cigarette commercials on television and radio. But an advertising ban, as recently suggested by a member of the Federal Communications Commission (FCC), should be part of a broader plan to curb the vaping epidemic among America’s youth, […]

WashU weekly Neuroscience publications

“Predicting Alzheimer’s disease progression using multi-modal deep learning approach” (2019) Scientific Reports Predicting Alzheimer’s disease progression using multi-modal deep learning approach (2019) Scientific Reports, 9 (1), art. no. 1952, .  Lee, G.a b , Nho, K.c d , Kang, B.a , Sohn, K.-A.a , Kim, D.b e , Weiner, M.W.f , Aisen, P.g , Petersen, R.h , Jack, C.R., Jr.h , […]

WashU weekly Neuroscience publications

“Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles” (2019) Channels (Austin, Tex.) Regional differences in the expression of tetrodotoxin-sensitive inward Ca2+ and outward Cs+/K+ currents in mouse and human ventricles (2019) Channels (Austin, Tex.), 13 (1), pp. 72-87.  Wang, W.a , Mellor, R.L.a , Nerbonne, J.M.a b , Balke, C.W.a […]

WashU weekly Neuroscience publications

“Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease” (2019) Stroke Advances in Understanding Ischemic Stroke Physiology and the Impact of Vasculopathy in Children With Sickle Cell Disease (2019) Stroke, 50 (2), pp. 266-273.  Guilliams, K.P.a b , Fields, M.E.b , Dowling, M.M.c a From the Department of Neurology (K.P.G.), Washington University School […]

WashU weekly Neuroscience publications

“Neuronal evidence for good-based economic decisions under variable action costs” (2019) Nature Communications Neuronal evidence for good-based economic decisions under variable action costs (2019) Nature Communications, 10 (1), art. no. 393, .  Cai, X.a b c d , Padoa-Schioppa, C.a e f a Department of Neuroscience, Washington University in St Louis, St Louis, MO 63110, United States b NYU Shanghai, 1555 Century Avenue, […]

WashU weekly Neuroscience publications

“Cost-Effectiveness Analysis of Combined Dual Motor Nerve Transfers versus Alternative Surgical and Nonsurgical Management Strategies to Restore Shoulder Function Following Upper Brachial Plexus Injury” (2019) Neurosurgery Cost-Effectiveness Analysis of Combined Dual Motor Nerve Transfers versus Alternative Surgical and Nonsurgical Management Strategies to Restore Shoulder Function Following Upper Brachial Plexus Injury (2019) Neurosurgery, 84 (2), pp. 362-377.  Khalifeh, J.M.a , Dibble, […]

Brown School launches substance use disorder clinic

From the WashU Newsroom… The Brown School has partnered with Preferred Family Healthcare in St. Louis to launch the Community Academic Partnership on Addiction (CAPA), a teaching, learning and research clinic aimed at combating the opioid epidemic and treating other substance use disorders. “Our aim is to develop a system of shared resources for attacking this issue, in St. […]

WashU weekly Neuroscience publications

“Neuroimaging of individual differences: A latent variable modeling perspective” (2019) Neuroscience and Biobehavioral Reviews Neuroimaging of individual differences: A latent variable modeling perspective (2019) Neuroscience and Biobehavioral Reviews, 98, pp. 29-46.  Cooper, S.R., Jackson, J.J., Barch, D.M., Braver, T.S. Washington University in St. Louis, Psychological and Brain Sciences, St. Louis, MO, United States Abstract Neuroimaging data is being increasingly […]

WashU weekly Neuroscience publications

“Seizures as an early symptom of autosomal dominant Alzheimer’s disease” (2019) Neurobiology of Aging Seizures as an early symptom of autosomal dominant Alzheimer’s disease (2019) Neurobiology of Aging, 76, pp. 18-23.  Vöglein, J.a b , Noachtar, S.b , McDade, E.c , Quaid, K.A.d , Salloway, S.e , Ghetti, B.f , Noble, J.g , Berman, S.h , Chhatwal, J.i , […]

WashU weekly Neuroscience publications

“Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification” (2019) NeuroImage Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification (2019) NeuroImage, 188, pp. 473-482.  Yun, H.J.a b , Chung, A.W.a b , Vasung, L.a b , Yang, E.c , Tarui, T.a b d e […]

WashU weekly Neuroscience publications

“Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification” (2019) NeuroImage Automatic labeling of cortical sulci for the human fetal brain based on spatio-temporal information of gyrification (2019) NeuroImage, 188, pp. 473-482.  Yun, H.J.a b , Chung, A.W.a b , Vasung, L.a b , Yang, E.c , Tarui, T.a b d e […]

WashU weekly Neuroscience publications

“Perioperative gabapentin and post cesarean pain control: A systematic review and meta-analysis of randomized controlled trials” (2019) European Journal of Obstetrics Gynecology and Reproductive Biology Perioperative gabapentin and post cesarean pain control: A systematic review and meta-analysis of randomized controlled trials (2019) European Journal of Obstetrics Gynecology and Reproductive Biology, 233, pp. 98-106.  Felder, L.a , Saccone, G.b , […]

2018 in review: Making strides and discoveries on campus and around the globe

From the WashU Newsroom… The Source looks back at some of our most read and most shared stories of 2018. Highlights include good news (a new chancellor), bad news (even light drinking increases risk of death) and who knew news (“collective narcissism” is real and Virginians have it).   Read more at the Source.

WashU weekly Neuroscience publications

“Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network” (2019) Neurobiology of Aging Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network (2019) Neurobiology of Aging, 75, pp. 42-50.  Bussy, A.a b , Snider, B.J.a b , Coble, D.a […]

Brown School researcher to study mental health on global scale

$2.9 million NIMH grant will allow Leopoldo J. Cabassa to focus on Chile From the WashU Newsroom… Leopoldo J. Cabassa, associate professor at the Brown School at Washington University in St. Louis, is part of a team that has received a five-year, $2.9 million grant from the National Institute of Mental Health to study interventions […]

WashU weekly Neuroscience publications

“Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel” (2019) Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel (2019) Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids, 1864 (2), pp. 128-136.  Budelier, M.M.a , Cheng, W.W.L.a , […]

WashU weekly Neuroscience publications

“Ambient PM2.5 and O3 and their combined effects on prevalence of presbyopia among the elderly: A cross-sectional study in six low- and middle-income countries” (2019) Science of the Total Environment Ambient PM2.5 and O3 and their combined effects on prevalence of presbyopia among the elderly: A cross-sectional study in six low- and middle-income countries (2019) Science […]

WashU weekly Neuroscience publications

"Touch engages visual spatial contextual processing" (2018) Scientific Reports Touch engages visual spatial contextual processing (2018) Scientific Reports, 8 (1), art. no. 16637, .  Pérez-Bellido, A.a b , Pappal, R.D.a c , Yau, J.M.a a Department of Neuroscience, Baylor College of Medicine, Houston, One Baylor Plaza, Houston, TX 77030, United States b Radboud University, Donders Institute for Brain, Cognition and Behavior, Nijmegen, Netherlands […]

WashU weekly Neuroscience publications

“Conformational preferences and phase behavior of intrinsically disordered low complexity sequences: insights from multiscale simulations” (2019) Current Opinion in Structural Biology Conformational preferences and phase behavior of intrinsically disordered low complexity sequences: insights from multiscale simulations (2019) Current Opinion in Structural Biology, 56, pp. 1-10.  Ruff, K.M., Pappu, R.V., Holehouse, A.S. Department of Biomedical Engineering and Center for Biological […]

WashU weekly Neuroscience publications

“Pain And Opioid Systems, Implications In The Opioid Epidemic” (2019) Current Opinion in Behavioral Sciences Pain And Opioid Systems, Implications In The Opioid Epidemic (2019) Current Opinion in Behavioral Sciences, 26, pp. 69-74.  Massaly, N.a b c , Morón, J.A.a b c d a Department of Anesthesiology, Washington University in St. Louis, St. Louis, MO 63110, United States b Washington University […]

Volunteering has some surprising health benefits

Five tips for finding a volunteer project that will give back as much to you as you give it. From NBC News… We all have that friend who’s got her (or his) life together. She has a great job. He’s got a loving partner. She works out. He makes his own yogurt. And the cherry […]

WashU weekly Neuroscience publications

“Pain And Opioid Systems, Implications In The Opioid Epidemic” (2019) Current Opinion in Behavioral Sciences Pain And Opioid Systems, Implications In The Opioid Epidemic (2019) Current Opinion in Behavioral Sciences, 26, pp. 69-74.  Massaly, N.a b c , Morón, J.A.a b c d a Department of Anesthesiology, Washington University in St. Louis, St. Louis, MO 63110, United States b Washington University […]

WashU weekly Neuroscience publications

“Impact of fingolimod on clinical and magnetic resonance imaging outcomes in routine clinical practice: A retrospective analysis of the multiple sclerosis, clinical and MRI outcomes in the USA (MS-MRIUS) study” (2019) Multiple Sclerosis and Related Disorders Impact of fingolimod on clinical and magnetic resonance imaging outcomes in routine clinical practice: A retrospective analysis of the […]

WashU weekly Neuroscience publications

“Symptoms of social anxiety disorder and major depressive disorder: A network perspective” (2019) Journal of Affective Disorders Symptoms of social anxiety disorder and major depressive disorder: A network perspective (2019) Journal of Affective Disorders, 243, pp. 531-538.  Langer, J.K.a , Tonge, N.A.a c , Piccirillo, M.a c , Rodebaugh, T.L.a c , Thompson, R.J.a c , Gotlib, I.H.b d […]